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Query: GSN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GSN 0 0.114 0.350 -0.590

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GSN Ubiquitylation K360 -0.879 0.993 _AALK(gl)TASDFITK_

Background Information for GSN:


Pubmed-GSN »
Uniprot-GSN »
Biogrid-GSN »
ProteomicsDB-GSN »

Tumorportal-GSN »
COSMIC-GSN »
GenomeRNAi-GSN »
Genecards-GSN


Protein-protein Interactions for GSN
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DBN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNA Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH10 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACTBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACTR1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCL7C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAS2L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1949 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LSP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEXN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GSN
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Gelsolin-like_dom IPR007123 0.09
Category members Villin/Gelsolin IPR007122 0


Protein complexes (CORUM database) featuring GSN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 756 Prune-Gelsolin complex Database 0


Categories featuring GSN
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_877 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 0 1.25
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0048015 phosphatidylinositol-mediated signaling Database 0.98
Category members Pathway Pathway_920 REACTOME_AMYLOIDS 0 0.68
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0008154 actin polymerization or depolymerization Database 0.47
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0001726 ruffle Database 0.33
Category members Pathway Pathway_667 BIOCARTA_RHO_PATHWAY 0 0.3
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members Pathway Pathway_536 BIOCARTA_ECM_PATHWAY 0 0.25
Category members GO Category GO:0051016 barbed-end actin filament capping Database 0.21
Category members GO Category GO:0014003 oligodendrocyte development Database 0.21
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members Pathway Pathway_960 BIOCARTA_HIVNEF_PATHWAY 0 0.17
Category members GO Category GO:0071276 cellular response to cadmium ion Database 0.13
Category members Pathway Pathway_546 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY 0 0.13
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_1018 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS 0 0.11
Category members Pathway Pathway_499 KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS 0 0.1
Category members GO Category GO:0045471 response to ethanol Database 0.1
Category members GO Category GO:0051014 actin filament severing Database 0.1
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0051593 response to folic acid Database 0.01
Category members GO Category GO:0030041 actin filament polymerization Database 0.01
Category members Pathway Pathway_564 PID_AVB3_OPN_PATHWAY 0 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0030155 regulation of cell adhesion Database 0
Category members GO Category GO:0042060 wound healing Database 0
Category members GO Category GO:0042246 tissue regeneration Database 0
Category members GO Category GO:0060271 cilium morphogenesis Database 0


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