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Results for the Category
REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS
(Pathway_1018)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CASP8 1 1.120 -1.090
SPTAN1 1 1.040 -0.790
SPTAN1 1 1.040 -0.790 -0.323 -0.738 0.512 0.509
VIM 0 -0.880 0.930 0.524 0.219 -0.756
ADD1 0 0.440 0.020 -0.881 -0.757 1.191 -0.072
DBNL 0 0.940 -0.940 0.425
DBNL 0 1.040 -0.600 0.425
DBNL 0 0.940 -0.940 0.111 0.457 0.226
DBNL 0 1.040 -0.600 0.111 0.457 0.226
GSN 0 0.350 -0.590
CASP3 0 0.570 -0.390
CASP7 0 0.130 -0.130
MAPT 0 -0.190 0.150

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ADD1 Phosphorylation T11 -0.730 -0.576 _AAVVT(ph)SPPPTTAPHK_
ADD1 Phosphorylation S12 -1.409 -0.665 _AAVVTS(ph)PPPTTAPHK_
ADD1 Phosphorylation S64 0.260 _RVSMILQS(ph)PAFCEELESMIQEQFK_
ADD1 Ubiquitylation K140 0.386 _GSDSIAYDK(gl)GEK_
ADD1 Ubiquitylation K143 0.288 0.386 _GSDSIAYDKGEK(gl)_
ADD1 Phosphorylation S353 -0.425 -0.286 _S(ph)RSPGSPVGEGTGSPPK_
ADD1 Phosphorylation S355 -0.007 -0.345 _SRS(ph)PGSPVGEGTGSPPK_
ADD1 Phosphorylation S358 -0.346 -0.241 _SPGS(ph)PVGEGTGSPPK_
ADD1 Phosphorylation S366 -1.004 _SPGSPVGEGTGS(ph)PPKWQIGEQEFEALMR_
ADD1 Phosphorylation T429 -0.303 _YSDVEVPASVTGYSFASDGDSGT(ph)CSPLR_
ADD1 Phosphorylation S431 -0.176 -0.145 _KYSDVEVPASVTGYSFASDGDSGTCS(ph)PLR_
ADD1 Phosphorylation S436 0.937 0.639 _KYSDVEVPASVTGYSFASDGDSGTCSPLRHS(ph)FQK_
ADD1 Phosphorylation S483 -0.425 -1.128 _TSTS(ph)AVPNLFVPLNTNPK_
ADD1 Phosphorylation S586 -0.125 1.117 _QKGS(ph)EENLDEAR_
ADD1 Phosphorylation S726 0.518 0.668 _TPS(ph)FLKK_
CASP3 Ubiquitylation K11 -0.053 -0.687 _(ac)MENTENSVDSK(gl)SIK_
CASP3 Ubiquitylation K14 -0.455 -0.687 _SIK(gl)NLEPK_
CASP3 Ubiquitylation K57 -0.304 -1.817 _NFHK(gl)STGMTSR_
CASP3 Ubiquitylation K82 -0.268 -0.605 _NLK(gl)YEVR_
CASP7 Phosphorylation S16 0.096 -0.112 _(ac)ADDQGCIEEQGVEDS(ph)ANEDSVDAKPDR_
CASP7 Ubiquitylation K80 0.580 -0.044 _NFDK(gl)VTGMGVR_
CASP8 Ubiquitylation K183 1.917 _IINDYEEFSK(gl)ER_
CASP8 Ubiquitylation K461 -2.031 _NMGK(gl)QMPQPTFTLR_
DBNL Ubiquitylation K144 0.756 _ASGANYSFHK(gl)ESGR_
DBNL Ubiquitylation K164 -0.807 0.448 _FQDVGPQAPVGSVYQK(gl)TNAVSEIKR_
DBNL Ubiquitylation K172 -0.071 _TNAVSEIK(gl)R_
DBNL Phosphorylation S232 -0.858 _YQEQGGEAS(ph)PQR_
DBNL Phosphorylation S269 -0.006 -0.553 _AM(ox)S(ph)TTSISSPQPGK_
DBNL Phosphorylation S272 -0.752 -0.377 _AMS(ph)TTS(ph)ISSPQPGK_
DBNL Phosphorylation S274 -0.547 -0.544 _AM(ox)STTSIS(ph)SPQPGK_
DBNL Phosphorylation S275 -0.547 0.433 _AMSTTSISS(ph)PQPGK_
DBNL Ubiquitylation K280 0.113 _AMSTTSISSPQPGK(gl)LR_
DBNL Phosphorylation S283 -0.388 0.222 _LRS(ph)PFLQK_
DBNL Phosphorylation T291 0.823 -0.150 _QLT(ph)QPETHFGR_
GSN Ubiquitylation K360 -0.879 0.993 _AALK(gl)TASDFITK_
MAPT Phosphorylation S437 -2.106 -1.602 _HPTPGSSDPLIQPSSPAVCPEPPS(ph)SPK_
MAPT Phosphorylation S438 -2.106 -1.602 _HPTPGSSDPLIQPSSPAVCPEPPS(ph)SPK_
MAPT Phosphorylation S516 -0.589 _SGYSS(ph)PGSPGTPGSR_
MAPT Phosphorylation S519 -0.792 -1.278 _SGYSSPGS(ph)PGTPGSR_
MAPT Phosphorylation T548 -0.976 -0.803 _VAVVRT(ph)PPKS(ph)PSSAK_
MAPT Phosphorylation S552 -0.811 -0.801 _VAVVRT(ph)PPKS(ph)PSSAK_
MAPT Phosphorylation S717 -0.091 -0.193 _SPVVS(ph)GDTSPR_
MAPT Phosphorylation T720 -0.287 0.006 _SPVVSGDT(ph)SPR_
MAPT Phosphorylation S721 -0.091 -0.203 _SPVVSGDTS(ph)PR_
MAPT Phosphorylation S729 -0.160 _HLSNVS(ph)STGSIDMVDSPQLATLADEVSASLAK_
MAPT Phosphorylation S733 -0.413 -0.151 _HLSNVSSTGS(ph)IDMVDSPQLATLADEVSASLAK_
SPTAN1 Ubiquitylation K864 -0.012 _GNAMVEEGHFAAEDVKAK(gl)_
SPTAN1 Phosphorylation S1029 1.169 1.417 _LDPAQS(ph)ASRENLLEEQGSIALR_
SPTAN1 Phosphorylation S1031 1.169 1.397 _LDPAQSAS(ph)RENLLEEQGSIALR_
SPTAN1 Ubiquitylation K1187 0.393 -0.095 _DETDSK(gl)TASPWK_
SPTAN1 Ubiquitylation K1193 0.677 0.204 _TASPWK(gl)SAR_
SPTAN1 Phosphorylation S1217 0.717 0.823 _WRS(ph)LQQLAEER_
SPTAN1 Ubiquitylation K2057 1.535 0.543 _HVQSK(gl)AIEAR_
VIM Phosphorylation S25 -0.029 _M(ox)FGGPGTASRPS(ph)SSR_
VIM Phosphorylation S26 0.491 -0.489 _M(ox)FGGPGTASRPSS(ph)SR_
VIM Phosphorylation S55 0.010 _SLYAS(ph)SPGGVYATR_
VIM Phosphorylation S56 -1.044 0.170 _SLYASS(ph)PGGVYATR_
VIM Phosphorylation S73 -0.003 0.375 _LRSS(ph)VPGVR_
VIM Ubiquitylation K104 -0.285 0.120 _TNEK(gl)VELQELNDR_
VIM Ubiquitylation K120 -0.582 0.786 _FANYIDK(gl)VR_
VIM Ubiquitylation K139 -0.472 0.704 _ILLAELEQLK(gl)GQGK_
VIM Ubiquitylation K143 -0.705 _ILLAELEQLKGQGK(gl)SR_
VIM Ubiquitylation K168 0.300 0.420 _RQVDQLTNDK(gl)AR_
VIM Ubiquitylation K188 0.146 0.024 _LREK(gl)LQEEMLQR_
VIM Ubiquitylation K235 -0.092 _KVESLQEEIAFLK(gl)K_
VIM Ubiquitylation K282 -0.294 _QQYESVAAK(gl)NLQEAEEWYK_
VIM Ubiquitylation K292 -0.491 0.405 _NLQEAEEWYK(gl)SK_
VIM Ubiquitylation K294 -0.447 0.397 _SK(gl)FADLSEAANR_
VIM Ubiquitylation K313 -0.036 0.304 _QAK(gl)QESTEYRR_
VIM Ubiquitylation K334 -0.057 0.450 _QVQSLTCEVDALK(gl)GTNESLER_
VIM Ubiquitylation K373 -0.435 1.135 _LQDEIQNM(ox)K(gl)EEMAR_
VIM Phosphorylation S409 -0.591 _LLEGEES(ph)RISLPLPNFSSLNLR_
VIM Phosphorylation S412 -0.514 -0.381 _IS(ph)LPLPNFSSLNLR_
VIM Phosphorylation S419 -0.492 _ISLPLPNFS(ph)SLNLR_
VIM Phosphorylation S420 -0.473 -0.087 _ISLPLPNFSS(ph)LNLR_
VIM Phosphorylation T426 -0.694 0.166 _ET(ph)NLDSLPLVDTHSK_
VIM Phosphorylation S430 -0.850 0.053 _ETNLDS(ph)LPLVDTHSK_
VIM Ubiquitylation K439 -0.337 -0.056 _ETNLDSLPLVDTHSK(gl)R_
VIM Ubiquitylation K445 0.260 0.578 _TLLIK(gl)TVETR_


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