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Query: VIM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VIM 0 3.755 -0.880 0.930 0.524 0.219 -0.756

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VIM Ubiquitylation K373 -0.435 1.135 _LQDEIQNM(ox)K(gl)EEMAR_
VIM Ubiquitylation K120 -0.582 0.786 _FANYIDK(gl)VR_
VIM Ubiquitylation K139 -0.472 0.704 _ILLAELEQLK(gl)GQGK_
VIM Ubiquitylation K445 0.260 0.578 _TLLIK(gl)TVETR_
VIM Ubiquitylation K334 -0.057 0.450 _QVQSLTCEVDALK(gl)GTNESLER_
VIM Ubiquitylation K168 0.300 0.420 _RQVDQLTNDK(gl)AR_
VIM Ubiquitylation K292 -0.491 0.405 _NLQEAEEWYK(gl)SK_
VIM Ubiquitylation K294 -0.447 0.397 _SK(gl)FADLSEAANR_
VIM Phosphorylation S73 -0.003 0.375 _LRSS(ph)VPGVR_
VIM Ubiquitylation K313 -0.036 0.304 _QAK(gl)QESTEYRR_
VIM Phosphorylation S56 -1.044 0.170 _SLYASS(ph)PGGVYATR_
VIM Phosphorylation T426 -0.694 0.166 _ET(ph)NLDSLPLVDTHSK_
VIM Ubiquitylation K104 -0.285 0.120 _TNEK(gl)VELQELNDR_
VIM Phosphorylation S430 -0.850 0.053 _ETNLDS(ph)LPLVDTHSK_
VIM Ubiquitylation K188 0.146 0.024 _LREK(gl)LQEEMLQR_
VIM Phosphorylation S55 0.010 _SLYAS(ph)SPGGVYATR_
VIM Ubiquitylation K439 -0.337 -0.056 _ETNLDSLPLVDTHSK(gl)R_
VIM Phosphorylation S420 -0.473 -0.087 _ISLPLPNFSS(ph)LNLR_
VIM Phosphorylation S412 -0.514 -0.381 _IS(ph)LPLPNFSSLNLR_
VIM Phosphorylation S26 0.491 -0.489 _M(ox)FGGPGTASRPSS(ph)SR_
VIM Phosphorylation S409 -0.591 _LLEGEES(ph)RISLPLPNFSSLNLR_
VIM Phosphorylation S25 -0.029 _M(ox)FGGPGTASRPS(ph)SSR_
VIM Ubiquitylation K143 -0.705 _ILLAELEQLKGQGK(gl)SR_
VIM Ubiquitylation K235 -0.092 _KVESLQEEIAFLK(gl)K_
VIM Ubiquitylation K282 -0.294 _QQYESVAAK(gl)NLQEAEEWYK_
VIM Phosphorylation S419 -0.492 _ISLPLPNFS(ph)SLNLR_

Background Information for VIM:


Pubmed-VIM »
Uniprot-VIM »
Biogrid-VIM »
ProteomicsDB-VIM »

Tumorportal-VIM »
COSMIC-VIM »
GenomeRNAi-VIM »
Genecards-VIM


Protein-protein Interactions for VIM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait VIM Cat. description Hein, Mann, Cell 2015
Category members IP bait CAPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GXYLT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VIM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Intermed_filament_DNA-bd IPR006821 0.07
Category members IF IPR001664 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring VIM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VIM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members Pathway Pathway_877 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members Pathway Pathway_911 PID_AURORA_B_PATHWAY 0 0.48
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0006928 cellular component movement Database 0.24
Category members Pathway Pathway_961 PID_CASPASE_PATHWAY 0 0.19
Category members Pathway Pathway_1018 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS 0 0.11
Category members GO Category GO:0003725 double-stranded RNA binding Database 0.1
Category members GO Category GO:0010977 negative regulation of neuron projection development Database 0.04
Category members GO Category GO:0045103 intermediate filament-based process Database 0.04
Category members GO Category GO:0060020 Bergmann glial cell differentiation Database 0.04
Category members Pathway Pathway_1208 REACTOME_STRIATED_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_950 REACTOME_MUSCLE_CONTRACTION 0 0
Category members Disease phenotype Pulverulent_cataract Pulverulent cataract Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0005212 structural constituent of eye lens Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0005882 intermediate filament Database 0
Category members GO Category GO:0014002 astrocyte development Database 0
Category members GO Category GO:0030049 muscle filament sliding Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0045109 intermediate filament organization Database 0
Category members GO Category GO:0070307 lens fiber cell development Database 0


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