Results for the Category
REACTOME_STRIATED_MUSCLE_CONTRACTION
(Pathway_1208)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| ACTN2 | 3 | -1.480 | 2.640 | 0.936 | 1.929 | -1.407 | 0.572 | 0.293 |
| ACTN2 | 3 | -1.480 | 2.640 | 0.790 | 0.055 | 0.246 | ||
| TPM3 | 1 | 2.410 | -1.030 | -0.178 | 0.366 | -0.380 | 0.330 | -1.062 |
| TPM3 | 1 | 2.410 | -1.030 | -1.315 | ||||
| DMD | 1 | 0.960 | -0.560 | 0.854 | 0.214 | |||
| VIM | 0 | -0.880 | 0.930 | 0.524 | 0.219 | -0.756 | ||
| TMOD1 | 0 | -0.360 | -0.060 | 0.837 | -0.008 | |||
| TPM1 | 0 | 0.280 | -0.190 | |||||
| MYL3 | 0 | -0.170 | 0.260 | |||||
| TPM4 | 0 | 1.200 | 0.010 | -0.178 | 0.366 | -0.380 | 0.330 | -1.062 |
| MYL1 | 0 | -0.430 | 0.790 | |||||
| MYH6 | 0 | -0.350 | 1.110 | |||||
| MYH6 | 0 | -0.240 | -0.750 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ACTN2 | Ubiquitylation | K125 | 1.906 | _ALDFIASKGVK(gl)_ | |
| ACTN2 | Ubiquitylation | K350 | 0.585 | _VQEK(gl)CQLEINFNTLQTK_ | |
| ACTN2 | Ubiquitylation | K417 | 0.789 | _LDHLAEK(gl)FR_ | |
| ACTN2 | Ubiquitylation | K592 | -0.644 | 0.678 | _EAILAIHK(gl)EAQR_ |
| ACTN2 | Ubiquitylation | K760 | 0.273 | 1.507 | _DAK(gl)GISQEQMQEFR_ |
| DMD | Ubiquitylation | K3317 | -0.200 | -0.978 | _CNICK(gl)ECPIIGFR_ |
| DMD | Phosphorylation | S3623 | 2.940 | 0.225 | _SDS(ph)SQPMLLR_ |
| MYH6 | Ubiquitylation | K1446 | -1.408 | -0.411 | _SNAAAAALDK(gl)K_ |
| MYH6 | Ubiquitylation | K1447 | -1.408 | -0.411 | _SNAAAAALDK(gl)K_ |
| MYL1 | Ubiquitylation | K142 | 1.113 | _VFDK(gl)EGNGTVMGAELR_ | |
| MYL3 | Ubiquitylation | K142 | 1.113 | _VFDK(gl)EGNGTVMGAELR_ | |
| TPM1 | Ubiquitylation | K30 | -1.537 | _AEQAEADKK(gl)AAEDR_ | |
| TPM3 | Ubiquitylation | K11 | 0.368 | 1.125 | _(ac)AGITTIEAVK(gl)R_ |
| TPM3 | Ubiquitylation | K116 | -0.031 | _MELQEIQLKEAK(gl)_ | |
| TPM3 | Ubiquitylation | K223 | 0.612 | _TIDDLEDK(gl)LK_ | |
| TPM3 | Ubiquitylation | K225 | 0.564 | _TIDDLEDKLK(gl)CTK_ | |
| TPM3 | Ubiquitylation | K228 | 1.242 | 0.668 | _CTK(gl)EEHLCTQR_ |
| TPM4 | Ubiquitylation | K11 | 0.368 | 1.125 | _(ac)AGITTIEAVK(gl)R_ |
| TPM4 | Ubiquitylation | K116 | -0.031 | _MELQEIQLKEAK(gl)_ | |
| TPM4 | Ubiquitylation | K223 | 0.612 | _TIDDLEDK(gl)LK_ | |
| TPM4 | Ubiquitylation | K225 | 0.564 | _TIDDLEDKLK(gl)CTK_ | |
| TPM4 | Ubiquitylation | K228 | 1.242 | 0.668 | _CTK(gl)EEHLCTQR_ |
| VIM | Phosphorylation | S25 | -0.029 | _M(ox)FGGPGTASRPS(ph)SSR_ | |
| VIM | Phosphorylation | S26 | 0.491 | -0.489 | _M(ox)FGGPGTASRPSS(ph)SR_ |
| VIM | Phosphorylation | S55 | 0.010 | _SLYAS(ph)SPGGVYATR_ | |
| VIM | Phosphorylation | S56 | -1.044 | 0.170 | _SLYASS(ph)PGGVYATR_ |
| VIM | Phosphorylation | S73 | -0.003 | 0.375 | _LRSS(ph)VPGVR_ |
| VIM | Ubiquitylation | K104 | -0.285 | 0.120 | _TNEK(gl)VELQELNDR_ |
| VIM | Ubiquitylation | K120 | -0.582 | 0.786 | _FANYIDK(gl)VR_ |
| VIM | Ubiquitylation | K139 | -0.472 | 0.704 | _ILLAELEQLK(gl)GQGK_ |
| VIM | Ubiquitylation | K143 | -0.705 | _ILLAELEQLKGQGK(gl)SR_ | |
| VIM | Ubiquitylation | K168 | 0.300 | 0.420 | _RQVDQLTNDK(gl)AR_ |
| VIM | Ubiquitylation | K188 | 0.146 | 0.024 | _LREK(gl)LQEEMLQR_ |
| VIM | Ubiquitylation | K235 | -0.092 | _KVESLQEEIAFLK(gl)K_ | |
| VIM | Ubiquitylation | K282 | -0.294 | _QQYESVAAK(gl)NLQEAEEWYK_ | |
| VIM | Ubiquitylation | K292 | -0.491 | 0.405 | _NLQEAEEWYK(gl)SK_ |
| VIM | Ubiquitylation | K294 | -0.447 | 0.397 | _SK(gl)FADLSEAANR_ |
| VIM | Ubiquitylation | K313 | -0.036 | 0.304 | _QAK(gl)QESTEYRR_ |
| VIM | Ubiquitylation | K334 | -0.057 | 0.450 | _QVQSLTCEVDALK(gl)GTNESLER_ |
| VIM | Ubiquitylation | K373 | -0.435 | 1.135 | _LQDEIQNM(ox)K(gl)EEMAR_ |
| VIM | Phosphorylation | S409 | -0.591 | _LLEGEES(ph)RISLPLPNFSSLNLR_ | |
| VIM | Phosphorylation | S412 | -0.514 | -0.381 | _IS(ph)LPLPNFSSLNLR_ |
| VIM | Phosphorylation | S419 | -0.492 | _ISLPLPNFS(ph)SLNLR_ | |
| VIM | Phosphorylation | S420 | -0.473 | -0.087 | _ISLPLPNFSS(ph)LNLR_ |
| VIM | Phosphorylation | T426 | -0.694 | 0.166 | _ET(ph)NLDSLPLVDTHSK_ |
| VIM | Phosphorylation | S430 | -0.850 | 0.053 | _ETNLDS(ph)LPLVDTHSK_ |
| VIM | Ubiquitylation | K439 | -0.337 | -0.056 | _ETNLDSLPLVDTHSK(gl)R_ |
| VIM | Ubiquitylation | K445 | 0.260 | 0.578 | _TLLIK(gl)TVETR_ |
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