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Query: DBNL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DBNL 0 3.568 0.940 -0.940 0.111 0.457 0.226
DBNL 0 3.568 0.940 -0.940 0.425
DBNL 0 3.568 1.040 -0.600 0.111 0.457 0.226
DBNL 0 3.568 1.040 -0.600 0.425

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DBNL Ubiquitylation K164 -0.807 0.448 _FQDVGPQAPVGSVYQK(gl)TNAVSEIKR_
DBNL Phosphorylation S275 -0.547 0.433 _AMSTTSISS(ph)PQPGK_
DBNL Phosphorylation S283 -0.388 0.222 _LRS(ph)PFLQK_
DBNL Phosphorylation T291 0.823 -0.150 _QLT(ph)QPETHFGR_
DBNL Phosphorylation S272 -0.752 -0.377 _AMS(ph)TTS(ph)ISSPQPGK_
DBNL Phosphorylation S274 -0.547 -0.544 _AM(ox)STTSIS(ph)SPQPGK_
DBNL Phosphorylation S269 -0.006 -0.553 _AM(ox)S(ph)TTSISSPQPGK_
DBNL Phosphorylation S232 -0.858 _YQEQGGEAS(ph)PQR_
DBNL Ubiquitylation K144 0.756 _ASGANYSFHK(gl)ESGR_
DBNL Ubiquitylation K172 -0.071 _TNAVSEIK(gl)R_
DBNL Ubiquitylation K280 0.113 _AMSTTSISSPQPGK(gl)LR_

Background Information for DBNL:


Pubmed-DBNL »
Uniprot-DBNL »
Biogrid-DBNL »
ProteomicsDB-DBNL »

Tumorportal-DBNL »
COSMIC-DBNL »
GenomeRNAi-DBNL »
Genecards-DBNL


Protein-protein Interactions for DBNL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DBNL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DBNL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ADF-H IPR002108 0.83
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring DBNL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DBNL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members Pathway Pathway_876 REACTOME_APOPTOTIC_EXECUTION_PHASE 0 2.5
Category members Pathway Pathway_837 REACTOME_APOPTOSIS 0 2.39
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_877 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0051015 actin filament binding Database 0.99
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0002102 podosome Database 0.3
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0030665 clathrin-coated vesicle membrane Database 0.24
Category members GO Category GO:0008047 enzyme activator activity Database 0.15
Category members Pathway Pathway_1018 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS 0 0.11
Category members Pathway Pathway_687 PID_TCR_PATHWAY 0 0.08
Category members GO Category GO:0007257 activation of JUN kinase activity Database 0.08
Category members Pathway Pathway_1059 PID_TCR_JNK_PATHWAY 0 0.04
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0007416 synapse assembly Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0016601 Rac protein signal transduction Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0


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