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Query: ALDH1A2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ALDH1A2 0 0.863 -1.010 0.740

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ALDH1A2 Ubiquitylation K507 0.123 _EYSEVK(gl)TVTVK_
ALDH1A2 Ubiquitylation K365 -1.744 _VVGSPFDPTTEQGPQIDK(gl)K_
ALDH1A2 Ubiquitylation K366 -1.744 _VVGSPFDPTTEQGPQIDK(gl)K_

Background Information for ALDH1A2:


Pubmed-ALDH1A2 »
Uniprot-ALDH1A2 »
Biogrid-ALDH1A2 »
ProteomicsDB-ALDH1A2 »

Tumorportal-ALDH1A2 »
COSMIC-ALDH1A2 »
GenomeRNAi-ALDH1A2 »
Genecards-ALDH1A2


Protein-protein Interactions for ALDH1A2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALDH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPZL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ALDH1A2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aldehyde_DH_dom IPR015590 0
Category members Ald_DH/histidinol_DH IPR016161 0


Protein complexes (CORUM database) featuring ALDH1A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ALDH1A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0001889 liver development Database 0.51
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0035799 ureter maturation Database 0.33
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0048566 embryonic digestive tract development Database 0.24
Category members GO Category GO:0060324 face development Database 0.08
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members GO Category GO:0042573 retinoic acid metabolic process Database 0.05
Category members GO Category GO:0043010 camera-type eye development Database 0.05
Category members GO Category GO:0001936 regulation of endothelial cell proliferation Database 0.04
Category members GO Category GO:0009954 proximal/distal pattern formation Database 0.04
Category members GO Category GO:0001758 retinal dehydrogenase activity Database 0.03
Category members GO Category GO:0021915 neural tube development Database 0.03
Category members GO Category GO:0030902 hindbrain development Database 0.02
Category members GO Category GO:0031016 pancreas development Database 0.01
Category members GO Category GO:0007494 midgut development Database 0.01
Category members Pathway Pathway_87 KEGG_RETINOL_METABOLISM 0 0
Category members GO Category GO:0001568 blood vessel development Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0002138 retinoic acid biosynthetic process Database 0
Category members GO Category GO:0003007 heart morphogenesis Database 0
Category members GO Category GO:0004028 3-chloroallyl aldehyde dehydrogenase activity Database 0
Category members GO Category GO:0006776 vitamin A metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0014032 neural crest cell development Database 0
Category members GO Category GO:0016331 morphogenesis of embryonic epithelium Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Database 0
Category members GO Category GO:0016918 retinal binding Database 0
Category members GO Category GO:0021983 pituitary gland development Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0031076 embryonic camera-type eye development Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0033189 response to vitamin A Database 0
Category members GO Category GO:0034097 response to cytokine Database 0
Category members GO Category GO:0035115 embryonic forelimb morphogenesis Database 0
Category members GO Category GO:0042572 retinol metabolic process Database 0
Category members GO Category GO:0042574 retinal metabolic process Database 0
Category members GO Category GO:0042904 9-cis-retinoic acid biosynthetic process Database 0
Category members GO Category GO:0048384 retinoic acid receptor signaling pathway Database 0
Category members GO Category GO:0048738 cardiac muscle tissue development Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0071300 cellular response to retinoic acid Database 0


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