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Results for the Category
DNA damage checkpoint
(GO:0000077)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
USP28 2 1.150 -0.550
RIF1 2 1.420 -1.180 -2.063 0.240 0.005 0.360 0.288
CLSPN 2 0.600 -0.710 -0.324 0.360 -0.207
NBN 2 -0.220 -0.170 0.708 0.569 -0.563 0.354
MAPK14 2 -0.160 -0.350
PCNA 2 -0.730 0.380 0.679 1.154 0.572 0.718 0.782
INTS7 2 -0.680 0.690 1.885 2.319 -1.060 -0.081
CHEK1 2 -1.170 1.560
CHEK1 2 -1.170 1.560
ATRIP 2 -1.370 1.920 -0.656 0.735 0.448
CHEK2 2 0.530 0.100
H2AFX 2 -0.474 -0.395 0.182 0.824 0.499
H2AFX 2
TIPIN 1 0.660 -0.190
BRIP1 1 0.650 -0.340
TIPRL 1 -1.760 2.530
RAD9A 1 -2.070 3.350
ATR 1 -1.040 0.920 0.671 1.041 0.708
RAD1 0 0.550 0.120
ATM 0 0.398 0.474
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
ATR Ubiquitylation K32 -0.929 _ELGSATPEEYNTVVQK(gl)PR_
ATR Phosphorylation S435 0.516 0.284 _RLS(ph)SSLNPSK_
ATR Ubiquitylation K746 -1.823 _NLK(gl)ATSQHECSSSQLK_
ATR Ubiquitylation K1019 1.662 _TLGK(gl)QLNVNRR_
ATR Ubiquitylation K1600 -0.437 _FQALK(gl)AEK_
ATR Ubiquitylation K2106 -0.136 _AYEWEK(gl)AGR_
ATR Ubiquitylation K2604 0.657 1.118 _LQGVIK(gl)TR_
ATRIP Phosphorylation S224 -0.208 -0.178 _LAAPSVSHVS(ph)PR_
ATRIP Phosphorylation S239 0.401 _KNPSVVIKPEACS(ph)PQFGK_
ATRIP Phosphorylation S518 1.549 1.561 _SLVHRLS(ph)DGDM(ox)TSALR_
BRIP1 Phosphorylation S112 0.807 1.459 _HFNYPS(ph)TPPSER_
BRIP1 Phosphorylation T113 1.675 _HFNYPST(ph)PPSER_
BRIP1 Phosphorylation S206 -0.381 _INSFS(ph)PQKPPGHCSR_
BRIP1 Ubiquitylation K764 -0.462 _GK(gl)VSEGLDFSDDNAR_
BRIP1 Ubiquitylation K797 -0.723 0.188 _DLQVELK(gl)R_
BRIP1 Phosphorylation S1032 -0.789 -0.532 _ATPELGSSENSASS(ph)PPR_
BRIP1 Phosphorylation S1237 0.424 0.355 _NFKPS(ph)PSK_
CHEK1 Ubiquitylation K53 0.879 _AVDCPENIK(gl)K_
CHEK1 Ubiquitylation K54 0.738 _AVDCPENIKK(gl)_
CHEK1 Phosphorylation S296 -0.098 0.184 _VTS(ph)GGVSESPSGFSK_
CHEK1 Phosphorylation S300 1.091 _VTSGGVS(ph)ESPSGFSK_
CHEK1 Phosphorylation S302 1.750 _VTSGGVSES(ph)PSGFSK_
CHEK1 Phosphorylation S317 1.903 _HIQSNLDFS(ph)PVNSASSEENVK_
CHEK1 Ubiquitylation K399 -0.582 _ETCEK(gl)LGYQWK_
CHEK2 Phosphorylation S260 3.670 3.632 _KFAIGS(ph)AR_
CHEK2 Ubiquitylation K437 -0.826 _TQVSLK(gl)DQITSGK_
CLSPN Phosphorylation S260 2.501 2.218 _KEPSLESGVHS(ph)FEEGSELSK_
CLSPN Phosphorylation S720 2.698 2.613 _SLS(ph)SDSTLLLFK_
CLSPN Phosphorylation S810 -0.895 -0.754 _SPS(ph)PGLFR_
CLSPN Phosphorylation S833 -1.011 _LSEPS(ph)LPIEDSQDLYNASPEPK_
CLSPN Phosphorylation S846 -1.298 -0.477 _LSEPSLPIEDSQDLYNAS(ph)PEPK_
CLSPN Phosphorylation S950 -0.457 0.474 _FTS(ph)QDASTPASSELNK_
CLSPN Phosphorylation S968 -1.527 _ES(ph)SMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFR_
CLSPN Phosphorylation S969 -1.527 _ES(ph)SMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFR_
CLSPN Phosphorylation S1156 0.322 _NIDDASQMDLFHRDS(ph)DDDQTEEQLDESEAR_
CLSPN Phosphorylation S1289 -0.296 0.054 _NFVFHTLS(ph)PVKAEAAK_
H2AFX Ubiquitylation K116 -0.071 _ATIAGGGVIPHIHK(gl)SLIGK_
H2AFX Ubiquitylation K120 0.702 0.181 _K(gl)TSATVGPK_
H2AFX Ubiquitylation K121 1.548 0.818 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K122 1.238 -0.400 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K126 1.132 _KGQQK(gl)TV_
H2AFX Ubiquitylation K128 -0.411 0.117 _KTSATVGPK(gl)APSGGKK_
H2AFX Phosphorylation S140 1.817 1.205 _KATQAS(ph)QEY_
INTS7 Ubiquitylation K37 0.488 -0.203 _SGK(gl)LGEQCEAVVR_
INTS7 Ubiquitylation K105 0.142 0.425 _ILNVDEFVK(gl)R_
INTS7 Ubiquitylation K346 -0.289 _SSDLVK(gl)LAQECCYHNNR_
INTS7 Ubiquitylation K672 0.349 -0.651 _ISNQMK(gl)QSMEEFR_
INTS7 Ubiquitylation K867 -3.485 -2.366 _SGQDYK(gl)IPIDNM(ox)TNEMEQR_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
NBN Phosphorylation T335 -1.121 _T(ph)TTPGPSLSQGVSVDEK_
NBN Phosphorylation S341 3.085 _TTTPGPS(ph)LSQGVSVDEK_
NBN Phosphorylation S343 3.710 3.629 _TTTPGPSLS(ph)QGVSVDEK_
NBN Phosphorylation S397 2.719 1.458 _MLS(ph)QDAPTVK_
NBN Phosphorylation S432 -0.192 -0.395 _IPNYQLS(ph)PTK_
NBN Phosphorylation T434 -0.188 -0.683 _IPNYQLSPT(ph)KLPSINK_
NBN Phosphorylation S615 1.985 4.691 _IS(ph)QENEIGKK_
PCNA Ubiquitylation K13 0.209 2.207 _LVQGSILK(gl)K_
PCNA Ubiquitylation K14 0.233 2.833 _LVQGSILKK(gl)_
PCNA Ubiquitylation K80 0.570 1.579 _ILK(gl)CAGNEDIITLR_
PCNA Ubiquitylation K164 2.309 2.671 _DLSHIGDAVVISCAK(gl)DGVK_
PCNA Ubiquitylation K168 2.484 2.645 _DLSHIGDAVVISCAKDGVK(gl)_
PCNA Ubiquitylation K248 0.226 0.515 _IADMGHLK(gl)YYLAPK_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
RAD1 Ubiquitylation K46 0.748 _EHATCFATK(gl)NGIK_
RAD9A Phosphorylation S277 -0.249 -0.052 _DSLLDGHFVLATLSDTDSHSQDLGS(ph)PER_
RIF1 Phosphorylation S7 0.303 -0.353 _GQS(ph)PLAPLLETLEDPSASHGGQTDAYLTLTSR_
RIF1 Phosphorylation S402 -1.985 _GASS(ph)PYGAPGTPR_
RIF1 Phosphorylation T409 -1.985 _GASS(ph)PYGAPGT(ph)PR_
RIF1 Phosphorylation S782 0.666 _VKS(ph)PQRPSDWSK_
RIF1 Phosphorylation S1454 0.362 0.645 _S(ph)PLHIKDDVLPK_
RIF1 Phosphorylation S1542 0.082 0.706 _RAS(ph)QGLLSSIENSESDSSEAKEEGSR_
RIF1 Phosphorylation S1554 0.475 _RASQGLLSSIENSES(ph)DSSEAKEEGSR_
RIF1 Phosphorylation S1579 0.402 0.564 _SNES(ph)VDIQDQEEK_
RIF1 Phosphorylation S1616 1.504 1.400 _ATSEEDVSIKS(ph)PICEK_
RIF1 Phosphorylation S1688 0.724 0.987 _RDS(ph)FDNCSLGESSK_
RIF1 Ubiquitylation K1721 0.678 _TFQTLECQHK(gl)R_
RIF1 Phosphorylation S1873 2.712 1.678 _NVS(ph)QESLETKEEKPEETPK_
RIF1 Phosphorylation S2144 0.017 -0.130 _VEEPSQCLASGTAISELIIEDNNAS(ph)PQK_
RIF1 Phosphorylation S2161 -0.390 -0.598 _ELDPSLVSANDS(ph)PSGMQTR_
RIF1 Phosphorylation S2196 -0.223 _RSQEDEISS(ph)PVNK_
RIF1 Phosphorylation S2205 -1.368 _RVS(ph)FADPIYQAGLADDIDRR_
RIF1 Phosphorylation S2348 -0.973 -0.812 _TLPIRS(ph)PK_
RIF1 Phosphorylation S2393 1.433 1.571 _SLS(ph)PDEER_
TIPIN Ubiquitylation K141 0.882 _EVQTCLK(gl)R_
TIPIN Phosphorylation S222 1.642 _LLSNS(ph)QTLGNDMLMNTPR_
TIPIN Phosphorylation T224 2.069 _LLSNSQT(ph)LGNDMLMNTPR_
TIPRL Ubiquitylation K19 -1.493 _DFCFGPWK(gl)LTASK_
TIPRL Ubiquitylation K128 -0.719 0.075 _LK(gl)VVPTTDHIDTEK_
TIPRL Ubiquitylation K142 -1.196 _VVPTTDHIDTEKLK(gl)_
TIPRL Phosphorylation S265 1.062 _IDPNPADS(ph)QKSTQVE_
USP28 Phosphorylation S495 2.593 2.418 _ESTSTESSS(ph)QDVESTFSSPEDSLPK_
USP28 Phosphorylation S1053 -0.658 -0.698 _EPPTIRPNS(ph)PYDLCSR_


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