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Query: ATRIP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATRIP 2 5.557 -1.370 1.920 -0.656 0.735 0.448

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATRIP Phosphorylation S518 1.549 1.561 _SLVHRLS(ph)DGDM(ox)TSALR_
ATRIP Phosphorylation S239 0.401 _KNPSVVIKPEACS(ph)PQFGK_
ATRIP Phosphorylation S224 -0.208 -0.178 _LAAPSVSHVS(ph)PR_

Background Information for ATRIP:


Pubmed-ATRIP »
Uniprot-ATRIP »
Biogrid-ATRIP »
ProteomicsDB-ATRIP »

Tumorportal-ATRIP »
COSMIC-ATRIP »
GenomeRNAi-ATRIP »
Genecards-ATRIP


Protein-protein Interactions for ATRIP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATRIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FZD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIR3DL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST6GAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATRIP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Exonuclease IPR006055 0
Category members RNaseH-like_dom IPR012337 0


Protein complexes (CORUM database) featuring ATRIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 265 ATR-ATRIP complex Database 0.33


Categories featuring ATRIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_790 REACTOME_CELL_CYCLE_CHECKPOINTS 0 3.89
Category members Pathway Pathway_865 PID_ATR_PATHWAY 0 3.46
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0000077 DNA damage checkpoint Database 2.04
Category members Pathway Pathway_864 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS 0 1.21
Category members Pathway Pathway_873 PID_FANCONI_PATHWAY 0 1.09
Category members Pathway Pathway_863 REACTOME_G2_M_CHECKPOINTS 0 0.74
Category members Disease phenotype Seckel_syndrome Seckel syndrome Database 0.25
Category members Pathway Pathway_1248 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT 0 0.21
Category members Disease phenotype SYSTEMIC_LUPUS_ERYTHEMATOSUS SYSTEMIC LUPUS ERYTHEMATOSUS Database 0.13


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