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Query: INTS7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
INTS7 2 4.666 -0.680 0.690 1.885 2.319 -1.060 -0.081

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
INTS7 Ubiquitylation K105 0.142 0.425 _ILNVDEFVK(gl)R_
INTS7 Ubiquitylation K37 0.488 -0.203 _SGK(gl)LGEQCEAVVR_
INTS7 Ubiquitylation K346 -0.289 _SSDLVK(gl)LAQECCYHNNR_
INTS7 Ubiquitylation K672 0.349 -0.651 _ISNQMK(gl)QSMEEFR_
INTS7 Ubiquitylation K867 -3.485 -2.366 _SGQDYK(gl)IPIDNM(ox)TNEMEQR_

Background Information for INTS7:





Protein-protein Interactions for INTS7

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait BUB3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait CKAP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM40A Cat. description Hein, Mann, Cell 2015
Category members IP bait FGD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF1C Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA10 Cat. description Hein, Mann, Cell 2015
Category members IP bait PML Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait RALA Cat. description Hein, Mann, Cell 2015
Category members IP bait SUMO3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TGFBR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS26A Cat. description Hein, Mann, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLEC14A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FNDC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MGRN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTRK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMEL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPACA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEFF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TOR1AIP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in INTS7

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring INTS7

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1155 Integrator-RNAPII complex Database 5.97
Category members Corum 1153 Integrator complex Database 4.67
Category members Corum 1154 DSS1 complex Database 1.97


Categories featuring INTS7

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0032039 integrator complex Database 4.79
Category members GO Category GO:0016180 snRNA processing Database 4.67
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0000077 DNA damage checkpoint Database 2.04


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