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Query: CLSPN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CLSPN 2 5.140 0.600 -0.710 -0.324 0.360 -0.207

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CLSPN Phosphorylation S720 2.698 2.613 _SLS(ph)SDSTLLLFK_
CLSPN Phosphorylation S260 2.501 2.218 _KEPSLESGVHS(ph)FEEGSELSK_
CLSPN Phosphorylation S950 -0.457 0.474 _FTS(ph)QDASTPASSELNK_
CLSPN Phosphorylation S1156 0.322 _NIDDASQMDLFHRDS(ph)DDDQTEEQLDESEAR_
CLSPN Phosphorylation S1289 -0.296 0.054 _NFVFHTLS(ph)PVKAEAAK_
CLSPN Phosphorylation S846 -1.298 -0.477 _LSEPSLPIEDSQDLYNAS(ph)PEPK_
CLSPN Phosphorylation S810 -0.895 -0.754 _SPS(ph)PGLFR_
CLSPN Phosphorylation S833 -1.011 _LSEPS(ph)LPIEDSQDLYNASPEPK_
CLSPN Phosphorylation S968 -1.527 _ES(ph)SMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFR_
CLSPN Phosphorylation S969 -1.527 _ES(ph)SMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFR_

Background Information for CLSPN:





Protein-protein Interactions for CLSPN

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDCA8 Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPH Cat. description Hein, Mann, Cell 2015
Category members IP bait CLSPN Cat. description Hein, Mann, Cell 2015
Category members IP bait GJB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait LTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1BP Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH7 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5B Cat. description Hein, Mann, Cell 2015
Category members IP bait TIMELESS Cat. description Hein, Mann, Cell 2015
Category members IP bait TIPIN Cat. description Hein, Mann, Cell 2015
Category members IP bait GINS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CLSPN

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CLSPN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CLSPN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_865 PID_ATR_PATHWAY 0 3.46
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006921 cellular component disassembly involved in execution phase of apoptosis Database 2.98
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0000077 DNA damage checkpoint Database 2.04
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0018105 peptidyl-serine phosphorylation Database 0.18
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0033314 mitotic DNA replication checkpoint Database 0.08
Category members GO Category GO:0010997 anaphase-promoting complex binding Database 0.04
Category members GO Category GO:0031572 G2 DNA damage checkpoint Database 0
Category members GO Category GO:0032147 activation of protein kinase activity Database 0


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