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positive regulation of mitotic cell cycle
(GO:0045931)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PAFAH1B1 1 0.820 -0.330 1.632 0.711
EIF4E 1 -2.250 4.200 0.590 0.156
EIF4E 1 -2.250 4.200 0.369
EIF4EBP1 1 2.050 -1.320
PKN2 0 0.530 -0.200 -0.561 -0.138 0.314
ASNS 0 -0.720 0.410 -0.182 1.244 1.020
BIRC5 0 -0.309 -0.536
CDC25B 0 -0.180 0.320
RPS6KB1 0 0.850 -0.600
DUSP3 0 0.360 -0.500
USP22 0 -1.620 2.280 -0.102 -0.073 -0.208
FOXA1 0 1.190 -0.010
CCNB1 0 -0.410 -0.128 0.212 -0.166 -0.523
MDM2 0 -0.210 0.080
APP 0 0.100 -0.260 0.285
TERF1 0 -1.080 1.620
PRKCA 0 0.750 -0.690 0.349 0.585
PRKCA 0 0.750 -0.690
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501
STAT5B 0 0.670 -0.960

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APP Ubiquitylation K751 -1.778 -1.280 _HLSK(gl)M(ox)QQNGYENPTYK_
ASNS Ubiquitylation K244 -0.611 -0.778 _ILFNNAVK(gl)K_
ASNS Ubiquitylation K245 -0.477 -0.859 _ILFNNAVKK(gl)_
ASNS Ubiquitylation K445 -1.075 _NGIEK(gl)HLLR_
ASNS Ubiquitylation K478 -0.512 -0.416 _EAFSDGITSVK(gl)NSWFK_
ASNS Ubiquitylation K513 -1.163 _TK(gl)EGYYYR_
ASNS Ubiquitylation K556 0.064 _TLTHYK(gl)SAVKA_
BIRC5 Ubiquitylation K15 -1.446 _(ac)GAPTLPPAWQPFLK(gl)DHR_
BIRC5 Ubiquitylation K113 0.088 -0.061 _HSSGCAFLSVK(gl)K_
BIRC5 Ubiquitylation K114 -0.061 _HSSGCAFLSVK(gl)K_
CCNB1 Ubiquitylation K18 -0.455 _AK(gl)INMAGAK_
CCNB1 Ubiquitylation K36 -1.833 -2.301 _VPTAPAATSK(gl)PGLRPR_
CCNB1 Ubiquitylation K59 -0.659 _VSEQLQAK(gl)MPMK_
CCNB1 Ubiquitylation K288 0.578 _QMEMK(gl)ILR_
CDC25B Phosphorylation S117 -0.601 _EAFAQRPS(ph)SAPDLMCLSPDR_
CDC25B Phosphorylation S118 -0.832 _EAFAQRPS(ph)SAPDLMCLSPDR_
CDC25B Phosphorylation S241 -2.288 -1.005 _S(ph)VTPPEEQQEAEEPK_
CDC25B Phosphorylation T243 -1.445 _SVT(ph)PPEEQQEAEEPK_
CDC25B Phosphorylation S261 0.275 _S(ph)KSLCHDEIENLLDSDHR_
CDC25B Phosphorylation S263 0.184 _SKS(ph)LCHDEIENLLDSDHR_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
DUSP3 Ubiquitylation K116 -0.586 _AADFIDQALAQK(gl)NGR_
EIF4E Ubiquitylation K147 -0.433 0.065 _WLITLNK(gl)QQR_
EIF4EBP1 Phosphorylation Y34 -1.060 _RVVLGDGVQLPPGDY(ph)STTPGGTLFS(ph)TTPGGTR_
EIF4EBP1 Phosphorylation S35 -0.849 _RVVLGDGVQLPPGDYS(ph)TTPGGTLFS(ph)TTPGGTR_
EIF4EBP1 Phosphorylation T37 -0.768 -0.583 _RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR_
EIF4EBP1 Phosphorylation T41 -3.655 -0.903 _RVVLGDGVQLPPGDYST(ph)TPGGT(ph)LFSTTPGGTR_
EIF4EBP1 Phosphorylation S44 -0.796 _VVLGDGVQLPPGDYSTTPGGTLFS(ph)T(ph)TPGGTR_
EIF4EBP1 Phosphorylation T45 -0.727 _VVLGDGVQLPPGDYSTTPGGTLFS(ph)T(ph)TPGGTR_
EIF4EBP1 Phosphorylation T46 -0.890 -0.817 _RVVLGDGVQLPPGDYSTT(ph)PGGTLFSTT(ph)PGGTR_
EIF4EBP1 Phosphorylation S65 0.522 0.478 _NS(ph)PVTKT(ph)PPR_
EIF4EBP1 Phosphorylation T68 -1.621 -2.402 _NS(ph)PVT(ph)KTPPRDLPTIPGVTSPSSDEPPMEASQSHLR_
EIF4EBP1 Ubiquitylation K69 -1.171 -1.547 _NSPVTK(gl)TPPR_
EIF4EBP1 Phosphorylation T70 -0.702 -0.017 _NSPVTKT(ph)PPR_
EIF4EBP1 Phosphorylation T77 -1.921 -1.898 _TPPRDLPT(ph)IPGVTSPSSDEPPMEASQSHLR_
EIF4EBP1 Phosphorylation T82 1.253 _DLPTIPGVT(ph)SPSSDEPPMEASQSHLR_
EIF4EBP1 Phosphorylation S83 1.211 0.339 _DLPTIPGVTS(ph)PSSDEPPMEASQSHLR_
EIF4EBP1 Phosphorylation S96 -1.541 _DLPTIPGVTSPSSDEPPMEASQS(ph)HLRNSPEDK_
EIF4EBP1 Phosphorylation S101 -1.900 -1.976 _DLPTIPGVTSPSSDEPPMEASQSHLRNS(ph)PEDK_
FOXA1 Phosphorylation S331 -0.760 -0.866 _TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK_
MDM2 Phosphorylation S166 0.576 1.068 _AIS(ph)ETEENSDELSGER_
MDM2 Ubiquitylation K334 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K336 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K363 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K364 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K473 0.806 _NK(gl)PCPVCR_
PAFAH1B1 Ubiquitylation K76 -0.530 _LNEAK(gl)EEFTSGGPLGQK_
PKN2 Phosphorylation S110 -0.178 0.111 _LQELNAHIVVS(ph)DPEDITDCPR_
PKN2 Phosphorylation S360 -0.306 -0.065 _ATSVALPGWS(ph)PSETR_
PKN2 Ubiquitylation K385 0.967 _NLLK(gl)TDDLSNDVCAVLK_
PKN2 Ubiquitylation K447 0.735 _SLCAVK(gl)FLR_
PKN2 Ubiquitylation K502 1.448 _QQGK(gl)TFLR_
PKN2 Phosphorylation T527 -1.598 -1.740 _AIPT(ph)VNHSGTFSPQAPVPTTVPVVDVR_
PKN2 Phosphorylation S535 -1.794 _AIPTVNHSGTFS(ph)PQAPVPTTVPVVDVR_
PKN2 Phosphorylation S582 0.725 0.956 _AS(ph)SLGEIDESSELR_
PKN2 Phosphorylation S583 0.827 1.023 _ASS(ph)LGEIDESSELR_
PKN2 Ubiquitylation K930 -0.445 _VK(gl)PPFIPTIR_
PKN2 Phosphorylation T958 -1.135 -0.827 _GREDVSNFDDEFTSEAPILT(ph)PPREPR_
PRKCA Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCA Ubiquitylation K316 -0.522 -0.535 _LGPAGNK(gl)VISPSEDR_
RPS6KB1 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
RPS6KB1 Phosphorylation S447 -0.525 -0.458 _TPVS(ph)PVKFSPGDFWGR_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_
TERF1 Phosphorylation S11 -0.248 -0.254 _(ac)AEDVSSAAPS(ph)PR_
USP22 Ubiquitylation K35 0.350 _VDNWK(gl)QNLR_
USP22 Ubiquitylation K152 -1.310 -0.895 _FSTWEPTK(gl)R_
USP22 Ubiquitylation K159 -0.035 -0.557 _ELELLK(gl)HNPK_
USP22 Ubiquitylation K166 -0.657 -0.098 _K(gl)ITSNCTIGLR_
USP22 Ubiquitylation K382 -0.028 -1.061 _IK(gl)CSGCHSYQESTK_


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