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four-way junction helicase activity
(GO:0009378)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
VCP 2 1.650 -0.640 -0.182 0.578 -0.596 0.007 -0.036
PSMC4 1 -0.111 1.993 0.557
SPAST 1 -1.590 2.900
PSMC5 1 0.000 -0.100
PSMC5 1 0.000 -0.100 -0.084 0.014 0.198 -0.612
PSMC1 1 -0.370 0.950 -0.345 -0.122 0.523 0.050 0.292
WRNIP1 1 1.010 -0.780 -0.010 0.550 1.699
PEX1 1 -0.360 0.060 0.486 0.514
NVL 1 -1.590 2.580 -0.325 0.198 -0.446 0.040
PSMC3 1 -0.227 -0.102 0.203 1.582
RUVBL1 1 -2.280 5.280 0.726 0.246 0.680 0.325 0.277
KATNA1 1 -1.910 4.710
PSMC6 0 1.170 -0.580 -0.025 0.192
RFC5 0 0.500 -0.920
RFC5 0 0.500 -0.920 -1.112 -0.547 0.316 -0.391 0.586
VPS4B 0 -0.670 1.580
CHTF18 0 -1.120 1.460
CHTF18 0 -1.120 1.460 0.089
VPS4A 0 -1.530 -0.566
ATAD1 0 -1.600 2.330 -0.184 -0.183
SPATA5 0 0.280 0.150 -0.443 -0.332 -1.725 -0.799
WRN 0 -0.320 -0.170 0.180
KATNAL2 0 -0.870 0.930 -1.083 0.236 -1.224 -0.685 -0.367
SPATA5L1 0 0.670 -0.420 -0.864 -0.304
LONP1 0 -0.080 -0.060 0.483 0.449 -1.109 1.066 0.781
BLM 0 1.270 -0.830 -0.850 -0.141 0.144 0.151 0.149
BLM 0 1.270 -0.830
ATAD3C 0 -0.620 0.350 0.424 0.052

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATAD1 Ubiquitylation K65 -0.245 _QIGVK(gl)NVK_
ATAD1 Ubiquitylation K144 0.074 _TLIAK(gl)ATAK_
ATAD1 Ubiquitylation K263 0.156 -0.080 _FHINQPALK(gl)QR_
ATAD1 Ubiquitylation K274 0.570 0.005 _LILK(gl)NENVDR_
BLM Phosphorylation S144 1.234 _KLEFSSS(ph)PDSLSTINDWDDMDDFDTSETSK_
CHTF18 Phosphorylation S260 0.124 0.005 _GDAAS(ph)SPAPAASVGSSQGGAR_
CHTF18 Phosphorylation S261 0.124 1.066 _GDAASS(ph)PAPAASVGSSQGGAR_
CHTF18 Phosphorylation S1074 0.485 _VENS(ph)PQVDGSPPGLEGLLGGIGEK_
CHTF18 Phosphorylation S1080 -0.520 -0.468 _VENSPQVDGS(ph)PPGLEGLLGGIGEK_
KATNA1 Phosphorylation S170 -0.150 0.049 _NKS(ph)PAAVTEPETNK_
NVL Ubiquitylation K25 1.419 _VIQYLTSNK(gl)CGK_
NVL Ubiquitylation K85 1.492 -0.907 _NLTELEDEHLAK(gl)R_
PEX1 Ubiquitylation K349 0.125 _TK(gl)QNVLSPEK_
PEX1 Ubiquitylation K368 0.607 0.123 _QMSEPLDQK(gl)K_
PEX1 Ubiquitylation K369 -0.129 _QMSEPLDQKK(gl)_
PEX1 Phosphorylation T1179 2.277 0.592 _T(ph)ASQEGCQELTQEQR_
PEX1 Phosphorylation S1181 1.820 1.458 _TAS(ph)QEGCQELTQEQR_
PEX1 Phosphorylation S1211 0.326 -0.091 _SQS(ph)GEDESMNQPGPIK_
PSMC1 Ubiquitylation K23 -1.788 _K(gl)KYEPPVPTR_
PSMC1 Ubiquitylation K24 -0.104 1.174 _K(gl)YEPPVPTR_
PSMC1 Ubiquitylation K48 -1.854 -1.146 _GPDAASK(gl)LPLVTPHTQCR_
PSMC1 Ubiquitylation K91 1.245 _NQEQMKPLEEK(gl)QEEER_
PSMC1 Ubiquitylation K98 0.442 4.780 _SK(gl)VDDLR_
PSMC1 Ubiquitylation K258 0.143 _VVGSELIQK(gl)YLGDGPK_
PSMC1 Ubiquitylation K265 -1.189 _YLGDGPK(gl)LVR_
PSMC1 Ubiquitylation K326 0.108 0.246 _GDVK(gl)VIMATNR_
PSMC1 Ubiquitylation K359 -0.457 -0.853 _KIEFPLPDEK(gl)TK_
PSMC1 Ubiquitylation K361 -1.277 -0.679 _IEFPLPDEKTK(gl)_
PSMC1 Ubiquitylation K413 0.108 0.270 _MK(gl)VTNEDFKK_
PSMC1 Ubiquitylation K420 -0.156 0.859 _MKVTNEDFK(gl)K_
PSMC1 Ubiquitylation K421 0.068 0.648 _VTNEDFKK(gl)_
PSMC1 Ubiquitylation K429 -0.735 _SKENVLYK(gl)K_
PSMC1 Ubiquitylation K430 -0.618 _SKENVLYKK(gl)_
PSMC1 Phosphorylation T434 -0.194 0.263 _KQEGT(ph)PEGLYL_
PSMC3 Phosphorylation S9 -0.089 0.162 _(ac)MNLLPNIES(ph)PVTR_
PSMC3 Ubiquitylation K16 -0.007 _QEK(gl)MATVWDEAEQDGIGEEVLK_
PSMC3 Ubiquitylation K53 1.141 _LLDSEIK(gl)IMK_
PSMC3 Ubiquitylation K56 0.171 0.893 _IMK(gl)SEVLR_
PSMC3 Ubiquitylation K70 0.813 0.938 _VTHELQAMK(gl)DK_
PSMC3 Ubiquitylation K79 0.527 _IKENSEK(gl)IK_
PSMC3 Ubiquitylation K81 0.303 _IKENSEKIK(gl)_
PSMC3 Ubiquitylation K125 0.211 0.991 _CAVIK(gl)TSTR_
PSMC3 Ubiquitylation K146 -0.149 0.433 _LK(gl)PGDLVGVNK_
PSMC3 Ubiquitylation K245 0.156 0.587 _ACAAQTK(gl)ATFLK_
PSMC3 Ubiquitylation K276 0.816 1.261 _DAFALAK(gl)EK_
PSMC3 Ubiquitylation K278 0.568 _DAFALAKEK(gl)_
PSMC3 Ubiquitylation K300 0.061 0.623 _RFDSEK(gl)AGDREVQR_
PSMC3 Ubiquitylation K372 -0.011 -0.132 _K(gl)MNVSPDVNYEELAR_
PSMC3 Ubiquitylation K431 1.026 0.632 _K(gl)KANLQYYA_
PSMC3 Ubiquitylation K432 1.026 0.798 _K(gl)ANLQYYA_
PSMC4 Phosphorylation T25 -1.198 _AQDEIPALSVSRPQT(ph)GLSFLGPEPEDLEDLYSR_
PSMC4 Phosphorylation S28 -0.962 _AQDEIPALSVSRPQTGLS(ph)FLGPEPEDLEDLYSR_
PSMC4 Ubiquitylation K80 0.193 -0.348 _EFLHAQEEVK(gl)R_
PSMC4 Ubiquitylation K125 -0.394 -0.532 _ELLK(gl)PNASVALHK_
PSMC4 Ubiquitylation K238 -0.433 _VVGSEFVQK(gl)YLGEGPR_
PSMC4 Ubiquitylation K401 -0.658 _DFEK(gl)AYK_
PSMC4 Ubiquitylation K418 0.356 0.606 _DEQEHEFYK(gl)_
PSMC5 Ubiquitylation K7 0.167 _(ac)MELEEGK(gl)AGSGLR_
PSMC5 Ubiquitylation K15 -0.747 0.003 _(ac)ALDGPEQMELEEGK(gl)AGSGLR_
PSMC5 Ubiquitylation K55 -0.538 -0.039 _NELNAK(gl)VR_
PSMC5 Ubiquitylation K88 -0.430 -0.397 _VLVK(gl)VHPEGK_
PSMC5 Ubiquitylation K101 -1.062 _FVVDVDK(gl)NIDINDVTPNCR_
PSMC5 Ubiquitylation K130 -0.243 _ILPNK(gl)VDPLVSLMMVEK_
PSMC5 Ubiquitylation K330 2.949 _LDILK(gl)IHSR_
PSMC5 Ubiquitylation K346 0.008 _K(gl)IAELMPGASGAEVK_
PSMC5 Ubiquitylation K397 0.415 0.779 _DSEK(gl)NMSIK_
PSMC5 Ubiquitylation K402 0.363 _DSEK(gl)NMSIKK_
PSMC6 Ubiquitylation K7 0.253 0.732 _DK(gl)ALQDYR_
PSMC6 Ubiquitylation K20 -0.044 0.744 _LLEHK(gl)EIDGR_
PSMC6 Ubiquitylation K34 -0.419 _EQLK(gl)ELTK_
PSMC6 Ubiquitylation K197 0.526 _AVASQLDCNFLK(gl)_
PSMC6 Ubiquitylation K383 0.276 -0.218 _KLESK(gl)LDYKPV_
RFC5 Ubiquitylation K16 0.039 -0.820 _QQEQPAATK(gl)IR_
RFC5 Ubiquitylation K270 0.495 _NITELK(gl)TLK_
RUVBL1 Ubiquitylation K7 0.148 0.466 _MKIEEVK(gl)STTK_
RUVBL1 Ubiquitylation K171 0.030 -0.502 _QLK(gl)LDPSIFESLQK_
RUVBL1 Ubiquitylation K201 0.095 _VEAGDVIYIEANSGAVK(gl)R_
SPAST Phosphorylation S268 0.172 _APS(ph)YSGLSMVSGVK_
SPATA5 Ubiquitylation K590 0.453 _KQPNLPDVK(gl)VAGLVK_
SPATA5L1 Ubiquitylation K372 -1.127 _EVVIGTPTLK(gl)QR_
SPATA5L1 Ubiquitylation K477 -1.832 _LK(gl)QSIEWPLK_
SPATA5L1 Ubiquitylation K511 -0.655 _GVLLYGPPGCAK(gl)TTLVR_
SPATA5L1 Ubiquitylation K577 -0.866 _SASK(gl)TGCDVQER_
SPATA5L1 Ubiquitylation K663 -0.274 _LSILK(gl)VCTK_
VCP Phosphorylation S3 0.795 1.142 _(ac)AS(ph)GADSKGDDLSTAILK_
VCP Phosphorylation S7 0.312 0.941 _(ac)ASGADS(ph)KGDDLSTAILK_
VCP Ubiquitylation K8 -0.439 -0.154 _(ac)ASGADSK(gl)GDDLSTAILK_
VCP Ubiquitylation K18 -0.452 0.181 _GDDLSTAILK(gl)QK_
VCP Ubiquitylation K20 -0.512 0.529 _(ac)ASGADSKGDDLSTAILKQK(gl)_
VCP Ubiquitylation K60 0.678 0.493 _GDTVLLK(gl)GKK_
VCP Ubiquitylation K81 0.084 _EAVCIVLSDDTCSDEK(gl)IR_
VCP Ubiquitylation K109 -0.847 -0.260 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K112 -0.736 -0.276 _LGDVISIQPCPDVK(gl)YGK(gl)R_
VCP Ubiquitylation K148 -0.262 -0.087 _K(gl)GDIFLVR_
VCP Ubiquitylation K211 1.383 0.902 _K(gl)QLAQIK_
VCP Ubiquitylation K236 -0.526 -0.178 _AIGVK(gl)PPR_
VCP Ubiquitylation K251 -0.110 _GILLYGPPGTGK(gl)TLIAR_
VCP Ubiquitylation K336 0.522 _IVSQLLTLMDGLK(gl)QR_
VCP Ubiquitylation K386 1.339 0.706 _LEILQIHTK(gl)NM(ox)K_
VCP Ubiquitylation K389 0.568 1.195 _LEILQIHTKNMK(gl)_
VCP Ubiquitylation K505 0.377 0.794 _FLK(gl)FGMTPSK_
VCP Ubiquitylation K524 -0.528 _GVLFYGPPGCGK(gl)TLLAK_
VCP Ubiquitylation K529 -0.250 _GVLFYGPPGCGKTLLAK(gl)_
VCP Ubiquitylation K565 0.645 0.689 _EIFDK(gl)AR_
VCP Ubiquitylation K615 1.209 1.270 _VINQILTEMDGMSTKK(gl)_
VCP Ubiquitylation K651 -1.709 -0.719 _LDQLIYIPLPDEK(gl)SR_
VCP Ubiquitylation K658 0.362 0.711 _VAILK(gl)ANLR_
VCP Ubiquitylation K663 -0.839 _K(gl)SPVAKDVDLEFLAK_
VCP Ubiquitylation K668 -0.536 0.265 _SPVAK(gl)DVDLEFLAK_
VCP Ubiquitylation K696 1.574 1.691 _ACK(gl)LAIR_
VCP Ubiquitylation K754 0.510 0.939 _K(gl)YEMFAQTLQQSR_
VPS4B Phosphorylation S102 -0.658 -0.952 _EGQPSPADEKGNDS(ph)DGEGESDDPEK_
WRN Ubiquitylation K134 0.717 _MLLENKAVK(gl)_
WRN Phosphorylation S1133 0.363 0.023 _SIMVQS(ph)PEK_
WRNIP1 Ubiquitylation K62 -1.792 _AK(gl)GPSPPGAK_
WRNIP1 Phosphorylation S65 0.168 -0.233 _AKGPS(ph)PPGAK_
WRNIP1 Ubiquitylation K70 -0.818 _AKGPSPPGAK(gl)R_
WRNIP1 Phosphorylation S75 1.158 1.190 _RLS(ph)ESSALK_
WRNIP1 Phosphorylation S77 1.308 _RLSES(ph)SALK_
WRNIP1 Phosphorylation S92 -1.354 _QPATPTAAESS(ph)EGEGEEGDDGGETESR_
WRNIP1 Phosphorylation T116 0.306 -0.594 _ESYDAPPT(ph)PSGAR_
WRNIP1 Phosphorylation S153 0.097 0.198 _RPAAAAAAGSAS(ph)PR_
WRNIP1 Ubiquitylation K286 -0.301 _TTLAHIIASNSK(gl)K_
WRNIP1 Ubiquitylation K287 0.038 -0.307 _TTLAHIIASNSKK(gl)_
WRNIP1 Ubiquitylation K301 -0.013 0.247 _FVTLSATNAK(gl)TNDVR_
WRNIP1 Ubiquitylation K310 -0.143 -0.318 _TNDVRDVIK(gl)QAQNEK_
WRNIP1 Ubiquitylation K316 -0.017 -0.193 _QAQNEK(gl)SFFK_
WRNIP1 Ubiquitylation K482 0.152 0.133 _VLITENDVK(gl)EGLQR_
WRNIP1 Ubiquitylation K601 0.465 _SIEVYSAYNNVK(gl)ACLR_
WRNIP1 Ubiquitylation K627 -0.257 -0.631 _LMK(gl)DLGYGK_
WRNIP1 Ubiquitylation K633 0.181 -0.910 _DLGYGK(gl)GYK_
WRNIP1 Ubiquitylation K636 -1.995 _GYK(gl)YNPMYSEPVDQEYLPEELR_
WRNIP1 Ubiquitylation K661 -0.239 -0.645 _GVDFFK(gl)QR_


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