bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PEX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PEX1 1 5.525 -0.360 0.060 0.486 0.514

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PEX1 Phosphorylation S1181 1.820 1.458 _TAS(ph)QEGCQELTQEQR_
PEX1 Phosphorylation T1179 2.277 0.592 _T(ph)ASQEGCQELTQEQR_
PEX1 Ubiquitylation K368 0.607 0.123 _QMSEPLDQK(gl)K_
PEX1 Phosphorylation S1211 0.326 -0.091 _SQS(ph)GEDESMNQPGPIK_
PEX1 Ubiquitylation K369 -0.129 _QMSEPLDQKK(gl)_
PEX1 Ubiquitylation K349 0.125 _TK(gl)QNVLSPEK_

Background Information for PEX1:


Pubmed-PEX1 »
Uniprot-PEX1 »
Biogrid-PEX1 »
ProteomicsDB-PEX1 »

Tumorportal-PEX1 »
COSMIC-PEX1 »
GenomeRNAi-PEX1 »
Genecards-PEX1


Protein-protein Interactions for PEX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EXOSC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM174A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ICAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PEX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14
Category members CDC48_domain_2-like IPR029067 0.12
Category members Asp_de-COase-like_dom IPR009010 0.04


Protein complexes (CORUM database) featuring PEX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5213 Pex26-Pex6-Pex1 complex Database 0


Categories featuring PEX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0006625 protein targeting to peroxisome Database 0.35
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Disease phenotype adrenoleukodystrophy_neonatal_(NALD) adrenoleukodystrophy neonatal (NALD) Database 0
Category members Disease phenotype Infantile_Refsum_disease Infantile Refsum disease Database 0
Category members Disease phenotype infantile_Refsum_disease_(IRD) infantile Refsum disease (IRD) Database 0
Category members Disease phenotype NEONATAL_ADRENOLEUKODYSTROPHY NEONATAL ADRENOLEUKODYSTROPHY Database 0
Category members Disease phenotype ZELLWEGER_SYNDROME ZELLWEGER SYNDROME Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0007031 peroxisome organization Database 0
Category members GO Category GO:0016558 protein import into peroxisome matrix Database 0
Category members GO Category GO:0042623 ATPase activity, coupled Database 0


.

© Copyright Svejstrup Laboratory 2015