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Query: LONP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LONP1 0 1.610 -0.080 -0.060 0.483 0.449 -1.109 1.066 0.781

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for LONP1:


Pubmed-LONP1 »
Uniprot-LONP1 »
Biogrid-LONP1 »
ProteomicsDB-LONP1 »

Tumorportal-LONP1 »
COSMIC-LONP1 »
GenomeRNAi-LONP1 »
Genecards-LONP1


Protein-protein Interactions for LONP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CKAP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ESPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRPPRC Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf45 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C9orf173 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C9orf24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF12L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXRED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GCAT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC8A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPS24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEU4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASL10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPF3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LONP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_dyneun-rel_AAA IPR011704 2.54
Category members Ribosomal_S5_D2-typ_fold IPR020568 1.06
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14
Category members Pept_S16_N IPR003111 0
Category members Lon_bac/euk-typ IPR004815 0
Category members Pept_S16_C IPR008269 0
Category members PUA-like_domain IPR015947 0


Protein complexes (CORUM database) featuring LONP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LONP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0042645 mitochondrial nucleoid Database 0.61
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0043623 cellular protein complex assembly Database 0.45
Category members GO Category GO:0030163 protein catabolic process Database 0.38
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members GO Category GO:0051131 chaperone-mediated protein complex assembly Database 0.24
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0051880 G-quadruplex DNA binding Database 0.11
Category members GO Category GO:0004252 serine-type endopeptidase activity Database 0.05
Category members GO Category GO:0006515 misfolded or incompletely synthesized protein catabolic process Database 0.04
Category members GO Category GO:0009725 response to hormone Database 0.01
Category members GO Category GO:0000002 mitochondrial genome maintenance Database 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0003727 single-stranded RNA binding Database 0
Category members GO Category GO:0004176 ATP-dependent peptidase activity Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0010044 response to aluminum ion Database 0
Category members GO Category GO:0034599 cellular response to oxidative stress Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0051603 proteolysis involved in cellular protein catabolic process Database 0
Category members GO Category GO:0070182 DNA polymerase binding Database 0


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