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Query: VPS4B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS4B 0 -0.030 -0.670 1.580

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VPS4B Phosphorylation S102 -0.658 -0.952 _EGQPSPADEKGNDS(ph)DGEGESDDPEK_

Background Information for VPS4B:


Pubmed-VPS4B »
Uniprot-VPS4B »
Biogrid-VPS4B »
ProteomicsDB-VPS4B »

Tumorportal-VPS4B »
COSMIC-VPS4B »
GenomeRNAi-VPS4B »
Genecards-VPS4B


Protein-protein Interactions for VPS4B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait EPHA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RALA Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4B Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS4B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_dyneun-rel_AAA IPR011704 2.54
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members IstB_ATP-bd IPR002611 0.16
Category members ATPase_AAA_core IPR003959 0.14
Category members Vps4_C IPR015415 0.02
Category members MIT IPR007330 0


Protein complexes (CORUM database) featuring VPS4B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VPS4B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members GO Category GO:0005769 early endosome Database 1.26
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0051301 cell division Database 1.15
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0006813 potassium ion transport Database 0.11
Category members GO Category GO:0007032 endosome organization Database 0.11
Category members GO Category GO:0005770 late endosome Database 0.09
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0005774 vacuolar membrane Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0030301 cholesterol transport Database 0
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0032367 intracellular cholesterol transport Database 0
Category members GO Category GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway Database 0
Category members GO Category GO:0033993 response to lipid Database 0
Category members GO Category GO:0042623 ATPase activity, coupled Database 0


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