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Query: SPATA5L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPATA5L1 0 -1.442 0.670 -0.420 -0.864 -0.304

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPATA5L1 Ubiquitylation K663 -0.274 _LSILK(gl)VCTK_
SPATA5L1 Ubiquitylation K511 -0.655 _GVLLYGPPGCAK(gl)TTLVR_
SPATA5L1 Ubiquitylation K577 -0.866 _SASK(gl)TGCDVQER_
SPATA5L1 Ubiquitylation K372 -1.127 _EVVIGTPTLK(gl)QR_
SPATA5L1 Ubiquitylation K477 -1.832 _LK(gl)QSIEWPLK_

Background Information for SPATA5L1:


Pubmed-SPATA5L1 »
Uniprot-SPATA5L1 »
Biogrid-SPATA5L1 »
ProteomicsDB-SPATA5L1 »

Tumorportal-SPATA5L1 »
COSMIC-SPATA5L1 »
GenomeRNAi-SPATA5L1 »
Genecards-SPATA5L1


Protein-protein Interactions for SPATA5L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C1orf112 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait LDHD Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CINP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT81 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA5L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPATA5L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_dyneun-rel_AAA IPR011704 2.54
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14


Protein complexes (CORUM database) featuring SPATA5L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPATA5L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0031593 polyubiquitin binding Database 0.38
Category members GO Category GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process Database 0.08
Category members GO Category GO:0070842 aggresome assembly Database 0


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