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Query: SPATA5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPATA5 0 -2.846 0.280 0.150 -0.443 -0.332 -1.725 -0.799

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SPATA5 Ubiquitylation K590 0.453 _KQPNLPDVK(gl)VAGLVK_

Background Information for SPATA5:


Pubmed-SPATA5 »
Uniprot-SPATA5 »
Biogrid-SPATA5 »
ProteomicsDB-SPATA5 »

Tumorportal-SPATA5 »
COSMIC-SPATA5 »
GenomeRNAi-SPATA5 »
Genecards-SPATA5


Protein-protein Interactions for SPATA5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMD14 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CINP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA5L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPATA5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members ATPase_AAA_core IPR003959 0.14
Category members Asp_de-COase-like_dom IPR009010 0.04


Protein complexes (CORUM database) featuring SPATA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPATA5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0007283 spermatogenesis Database 0


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