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Query: VPS4A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VPS4A 0 -2.096 -1.530 -0.566

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for VPS4A:


Pubmed-VPS4A »
Uniprot-VPS4A »
Biogrid-VPS4A »
ProteomicsDB-VPS4A »

Tumorportal-VPS4A »
COSMIC-VPS4A »
GenomeRNAi-VPS4A »
Genecards-VPS4A


Protein-protein Interactions for VPS4A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPQ Cat. description Hein, Mann, Cell 2015
Category members IP bait NABP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMO Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM248 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS4A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VPS4A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_dyneun-rel_AAA IPR011704 2.54
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members IstB_ATP-bd IPR002611 0.16
Category members ATPase_AAA_core IPR003959 0.14
Category members Vps4_C IPR015415 0.02
Category members MIT IPR007330 0


Protein complexes (CORUM database) featuring VPS4A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring VPS4A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members Pathway Pathway_645 PID_CXCR4_PATHWAY 0 1.42
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members Pathway Pathway_800 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 0 0.06
Category members GO Category GO:0031902 late endosome membrane Database 0
Category members GO Category GO:0042623 ATPase activity, coupled Database 0


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