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Query: WRNIP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WRNIP1 1 5.449 1.010 -0.780 -0.010 0.550 1.699

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WRNIP1 Phosphorylation S75 1.158 1.190 _RLS(ph)ESSALK_
WRNIP1 Ubiquitylation K301 -0.013 0.247 _FVTLSATNAK(gl)TNDVR_
WRNIP1 Phosphorylation S153 0.097 0.198 _RPAAAAAAGSAS(ph)PR_
WRNIP1 Ubiquitylation K482 0.152 0.133 _VLITENDVK(gl)EGLQR_
WRNIP1 Ubiquitylation K316 -0.017 -0.193 _QAQNEK(gl)SFFK_
WRNIP1 Phosphorylation S65 0.168 -0.233 _AKGPS(ph)PPGAK_
WRNIP1 Ubiquitylation K287 0.038 -0.307 _TTLAHIIASNSKK(gl)_
WRNIP1 Ubiquitylation K310 -0.143 -0.318 _TNDVRDVIK(gl)QAQNEK_
WRNIP1 Phosphorylation T116 0.306 -0.594 _ESYDAPPT(ph)PSGAR_
WRNIP1 Ubiquitylation K627 -0.257 -0.631 _LMK(gl)DLGYGK_
WRNIP1 Ubiquitylation K661 -0.239 -0.645 _GVDFFK(gl)QR_
WRNIP1 Ubiquitylation K633 0.181 -0.910 _DLGYGK(gl)GYK_
WRNIP1 Ubiquitylation K62 -1.792 _AK(gl)GPSPPGAK_
WRNIP1 Ubiquitylation K636 -1.995 _GYK(gl)YNPMYSEPVDQEYLPEELR_
WRNIP1 Ubiquitylation K70 -0.818 _AKGPSPPGAK(gl)R_
WRNIP1 Phosphorylation S77 1.308 _RLSES(ph)SALK_
WRNIP1 Phosphorylation S92 -1.354 _QPATPTAAESS(ph)EGEGEEGDDGGETESR_
WRNIP1 Ubiquitylation K286 -0.301 _TTLAHIIASNSK(gl)K_
WRNIP1 Ubiquitylation K601 0.465 _SIEVYSAYNNVK(gl)ACLR_

Background Information for WRNIP1:


Pubmed-WRNIP1 »
Uniprot-WRNIP1 »
Biogrid-WRNIP1 »
ProteomicsDB-WRNIP1 »

Tumorportal-WRNIP1 »
COSMIC-WRNIP1 »
GenomeRNAi-WRNIP1 »
Genecards-WRNIP1


Protein-protein Interactions for WRNIP1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in WRNIP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members ATPase_dyneun-rel_AAA IPR011704 2.54
Category members DNA_helicase_Holl-junc_RuvB_N IPR008824 1.05
Category members AAA+_ATPase IPR003593 0.38
Category members IstB_ATP-bd IPR002611 0.16
Category members ATPase_AAA_core IPR003959 0.14
Category members DUF815 IPR008533 0.04
Category members Znf_Rad18_put IPR006642 0


Protein complexes (CORUM database) featuring WRNIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WRNIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0009378 four-way junction helicase activity Database 1.06
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0030174 regulation of DNA-dependent DNA replication initiation Database 0.04
Category members GO Category GO:0000731 DNA synthesis involved in DNA repair Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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