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translation factor activity, nucleic acid binding
(GO:0008135)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
EEF2K 2 -1.120 2.610
EIF2S2 2 -2.220 4.160 1.238 -0.784 0.387 0.537
EIF2S2 2 -2.220 4.160 -0.289
GCN1L1 1 1.290 -0.930 0.125 -0.510 0.357 0.076 0.016
EIF4G1 1 -1.660 2.810 0.765
EIF4G1 1 -1.660 2.810 -0.451 -0.932 -0.258 -0.331
EIF2S3 1 0.380 0.280 0.168
EIF2S3 1 0.380 0.280 0.842 -0.253 0.010
EIF1 1 -0.290 0.000 -0.543 0.178
EIF2B3 0 1.580 -0.430 -3.615 1.427 1.157
EIF4G3 0 -0.870 0.650 -0.609 -0.700
MTIF2 0 0.630 -0.750 -0.350 0.783 -0.267 0.657 0.874
EIF5 0 -0.340 0.160 0.483 0.493 0.323
EEF1A2 0 -0.110 0.350 0.078 -0.079
EEF1A2 0 -0.110 0.350
EEF1D 0 0.670 -0.720 0.227 0.315 -0.128 0.359 -0.603
EEF1D 0 0.670 -0.720
EIF4G2 0 0.700 0.050 -0.629 -0.963
EIF4G2 0 0.700 0.050 1.131 -0.729 0.052
GTF2H3 0 -0.020 0.680 1.408 0.908
EIF4E2 0 0.840 -0.580 -0.233 -0.963
EIF4A1 0 1.010 -0.810 0.605 -1.090 0.048 0.029
EIF4A1 0 1.010 -0.810 0.248
EIF1AX 0 0.722 0.019 0.663

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
EEF1A2 Ubiquitylation K179 0.816 _EVSAYIK(gl)K_
EEF1A2 Ubiquitylation K180 0.871 0.816 _EVSAYIKK(gl)_
EEF1A2 Ubiquitylation K392 0.713 _KLEDNPK(gl)SLK_
EEF1D Phosphorylation S2 -0.963 _GS(ph)DNEEEDKEAAQLR_
EEF1D Ubiquitylation K475 -0.153 0.845 _ENIQK(gl)SLAGSSGPGASSGTSGDHGELVVR_
EEF1D Ubiquitylation K533 0.273 _LNVLEK(gl)SSPGHR_
EEF1D Phosphorylation S549 -0.210 0.037 _ATAPQTQHVS(ph)PMR_
EEF1D Phosphorylation T563 -0.082 _KPAT(ph)PAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR_
EEF1D Phosphorylation S578 -0.456 -0.360 _KPAT(ph)PAEDDEDDDIDLFGS(ph)DNEEEDKEAAQLR_
EEF1D Ubiquitylation K604 -0.305 _AK(gl)KPALVAK_
EEF1D Ubiquitylation K605 -1.446 _AKK(gl)PALVAK_
EEF2K Phosphorylation S18 0.197 0.661 _LEGVDGGQS(ph)PR_
EEF2K Ubiquitylation K65 0.734 _YYSNLTK(gl)SER_
EEF2K Ubiquitylation K341 2.006 -0.155 _DAVNQNTK(gl)LLQSAK_
EEF2K Phosphorylation S445 -0.049 _ESENSGDSGYPS(ph)EKRGELDDPEPR_
EEF2K Phosphorylation S470 0.044 0.565 _KYES(ph)DEDSLGSSGR_
EEF2K Ubiquitylation K485 1.702 1.119 _VCVEK(gl)WNLLNSSR_
EIF1 Phosphorylation S2 -0.495 1.632 _S(ph)AIQNLHS(ph)FDPFADASK_
EIF1 Phosphorylation S9 0.497 1.631 _(ac)SAIQNLHS(ph)FDPFADASK_
EIF1 Ubiquitylation K42 0.075 _K(gl)TLTTVQGIADDYDKK_
EIF1 Ubiquitylation K109 1.332 0.610 _DDQLK(gl)VHGF_
EIF1AX Ubiquitylation K29 0.235 0.769 _ELVFK(gl)EDGQEYAQVIK_
EIF1AX Ubiquitylation K56 0.668 1.126 _LEAM(ox)CFDGVK(gl)R_
EIF1AX Ubiquitylation K88 -0.210 0.111 _DYQDNK(gl)ADVILK_
EIF1AX Ubiquitylation K94 0.441 1.037 _DYQDNKADVILK(gl)YNADEAR_
EIF1AX Ubiquitylation K104 0.257 0.111 _SLK(gl)AYGELPEHAK_
EIF2B3 Ubiquitylation K61 -0.836 -0.162 _DVQK(gl)ALCAEFK_
EIF2B3 Ubiquitylation K68 -0.565 _ALCAEFK(gl)MK_
EIF2B3 Ubiquitylation K148 -1.168 -1.682 _KGQDSIEPVPGQKGK(gl)_
EIF2B3 Ubiquitylation K165 -0.262 -0.491 _DFIGVDSTGK(gl)R_
EIF2B3 Ubiquitylation K382 -0.991 -0.264 _SVIGSSCLIK(gl)DR_
EIF2S2 Phosphorylation S2 0.392 0.407 _(ac)S(ph)GDEM(ox)IFDPTM(ox)SKK_
EIF2S2 Phosphorylation S105 0.614 0.180 _DLKIES(ph)DVQEPTEPEDDLDIMLGNK_
EIF2S2 Phosphorylation T111 0.393 -0.207 _IESDVQEPT(ph)EPEDDLDIMLGNKK_
EIF2S2 Ubiquitylation K190 -1.188 _EK(gl)NPDMVAGEK_
EIF2S2 Ubiquitylation K199 0.815 _EKNPDMVAGEK(gl)R_
EIF2S2 Ubiquitylation K265 1.379 _FQQK(gl)QIENVLR_
EIF2S2 Ubiquitylation K276 4.065 _YIK(gl)EYVTCHTCR_
EIF2S2 Ubiquitylation K293 -0.051 0.495 _SPDTILQK(gl)DTR_
EIF2S2 Ubiquitylation K324 0.924 0.471 _TGFQAVTGK(gl)R_
EIF2S3 Ubiquitylation K59 0.426 0.672 _STVVK(gl)AISGVHTVR_
EIF2S3 Ubiquitylation K70 -0.136 0.775 _FK(gl)NELER_
EIF2S3 Ubiquitylation K80 0.618 _NITIK(gl)LGYANAK_
EIF2S3 Ubiquitylation K87 -0.553 1.040 _LGYANAK(gl)IYK_
EIF2S3 Ubiquitylation K90 -1.279 -0.619 _IYK(gl)LDDPSCPRPECYR_
EIF2S3 Ubiquitylation K121 -1.264 0.000 _SCGSSTPDEFPTDIPGTK(gl)GNFK_
EIF2S3 Ubiquitylation K125 -0.886 1.674 _GNFK(gl)LVR_
EIF2S3 Ubiquitylation K196 -0.225 0.792 _IDLVK(gl)ESQAK_
EIF2S3 Ubiquitylation K275 0.154 _SFDVNKPGCEVDDLK(gl)GGVAGGSILK_
EIF2S3 Ubiquitylation K285 0.689 _GGVAGGSILK(gl)GVLK_
EIF2S3 Ubiquitylation K303 -0.429 0.020 _VGQEIEVRPGIVSK(gl)DSEGK_
EIF2S3 Ubiquitylation K308 -1.136 0.216 _DSEGK(gl)LMCKPIFSK_
EIF2S3 Ubiquitylation K312 -0.523 0.555 _LMCK(gl)PIFSK_
EIF2S3 Ubiquitylation K391 0.111 _LLGVRTEGDKK(gl)_
EIF2S3 Ubiquitylation K421 0.258 1.210 _VSAVK(gl)ADLGK_
EIF2S3 Ubiquitylation K440 0.386 1.041 _IVLTNPVCTEVGEK(gl)IALSR_
EIF2S3 Ubiquitylation K466 -0.588 0.203 _GVTIK(gl)PTVDDD_
EIF4A1 Ubiquitylation K54 0.141 0.814 _GIYAYGFEK(gl)PSAIQQR_
EIF4A1 Ubiquitylation K68 -0.187 0.201 _AILPCIK(gl)GYDVIAQAQSGTGK_
EIF4A1 Ubiquitylation K146 -1.101 -1.263 _AEVQK(gl)LQMEAPHIIVGTPGR_
EIF4A1 Ubiquitylation K174 -0.518 -0.258 _YLSPK(gl)YIK_
EIF4A1 Ubiquitylation K291 -0.226 _VDWLTEK(gl)MHAR_
EIF4A1 Ubiquitylation K309 0.062 -0.357 _DFTVSAMHGDMDQK(gl)ERDVIMR_
EIF4A1 Ubiquitylation K369 0.625 -0.611 _K(gl)GVAINM(ox)VTEEDK(gl)R_
EIF4A1 Ubiquitylation K381 -0.034 0.613 _K(gl)GVAINM(ox)VTEEDK(gl)R_
EIF4G1 Ubiquitylation K627 -0.658 _SDQWK(gl)PLNLEEK_
EIF4G1 Ubiquitylation K635 -1.721 -1.834 _SDQWKPLNLEEKK(gl)_
EIF4G1 Phosphorylation T672 -1.605 _ANKT(ph)PLRPLDPTR_
EIF4G1 Ubiquitylation K925 0.326 _SLGNIK(gl)FIGELFK_
EIF4G1 Ubiquitylation K975 -0.759 _DLDFEK(gl)AKPR_
EIF4G1 Phosphorylation T1098 -0.123 _IT(ph)KPGSIDSNNQLFAPGGR_
EIF4G1 Phosphorylation S1102 0.238 -0.562 _ITKPGS(ph)IDSNNQLFAPGGR_
EIF4G1 Phosphorylation S1117 -0.554 _ITKPGSIDSNNQLFAPGGRLS(ph)WGK_
EIF4G1 Phosphorylation S1210 0.417 1.061 _S(ph)FSKEVEER_
EIF4G1 Phosphorylation S1212 1.007 0.725 _RSFS(ph)KEVEER_
EIF4G1 Phosphorylation S1234 0.676 1.054 _AAS(ph)LTEDRDR_
EIF4G1 Phosphorylation T1236 1.002 _KAAS(ph)LTEDRDR_
EIF4G1 Phosphorylation S1256 -1.072 -0.563 _REAALPPVS(ph)PLK_
EIF4G1 Phosphorylation S1263 0.713 0.836 _AALS(ph)EEELEKK_
EIF4G2 Ubiquitylation K260 0.068 -1.066 _NVDVYDK(gl)R_
EIF4G2 Ubiquitylation K361 0.871 0.407 _MCSLMLSK(gl)ELPAR_
EIF4G2 Phosphorylation S454 -1.517 _MDRDPLGGLADMFGQMPGS(ph)GIGTGPGVIQDRFSPTMGR_
EIF4G2 Phosphorylation T458 -0.619 -1.448 _DPLGGLADMFGQMPGSGIGT(ph)GPGVIQDRFSPTM(ox)GR_
EIF4G2 Phosphorylation S468 -0.235 -0.781 _FS(ph)PTMGR_
EIF4G2 Phosphorylation T581 -1.576 -0.919 _TQT(ph)PPLGQTPQLGLK_
EIF4G3 Phosphorylation S428 -0.198 -0.408 _SPS(ph)PVLR_
EIF4G3 Phosphorylation S436 1.117 _LVLS(ph)GEKK_
EIF4G3 Phosphorylation S691 -0.438 -0.303 _S(ph)PVPAQIAITVPK_
EIF4G3 Phosphorylation S1352 0.654 0.877 _GGS(ph)SKDLLDNQSQEEQR_
EIF4G3 Phosphorylation S1353 0.803 -0.554 _GGS(ph)SKDLLDNQSQEEQRR_
EIF4G3 Phosphorylation S1605 0.606 0.554 _LDFIESDS(ph)PCSSEALSK_
GCN1L1 Ubiquitylation K12 0.453 0.104 _(ac)AADTQVSETLK(gl)R_
GCN1L1 Ubiquitylation K308 -0.980 _GLAGHLK(gl)SNSPR_
GCN1L1 Ubiquitylation K695 -0.495 _MK(gl)IDPEAFITR_
GCN1L1 Ubiquitylation K788 -0.424 _SIIQSAQQDSIK(gl)K_
GCN1L1 Ubiquitylation K789 0.255 -0.354 _SIIQSAQQDSIKK(gl)_
GCN1L1 Ubiquitylation K829 0.801 -0.151 _GIKEEVQLTSK(gl)QK_
GCN1L1 Ubiquitylation K1395 -0.248 _K(gl)GAAYGLAGLVK_
GCN1L1 Ubiquitylation K1514 -1.429 _TK(gl)AGSVELLGAMAYCAPK_
GCN1L1 Ubiquitylation K1556 0.235 _LTEVLTDSHVKVQK(gl)_
GCN1L1 Ubiquitylation K1679 1.567 -0.083 _TVSAK(gl)ALGAMVK_
GCN1L1 Ubiquitylation K2183 2.095 0.580 _SK(gl)ADYTSHLR_
GCN1L1 Ubiquitylation K2280 -0.810 _EGVLTGSPEQK(gl)EEAAK_
GTF2H3 Ubiquitylation K28 -0.741 _QALK(gl)ESQFTLSK_
GTF2H3 Ubiquitylation K74 -0.538 _FLYPGK(gl)NGR_
GTF2H3 Ubiquitylation K125 -0.584 -0.425 _SDIK(gl)GQHTETLLAGSLAK_
GTF2H3 Ubiquitylation K152 -0.594 _MNKEVK(gl)DNQEMK_
GTF2H3 Ubiquitylation K300 -1.837 _ISLPPVLKAK(gl)_


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