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Query: EEF1A2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EEF1A2 0 2.036 -0.110 0.350
EEF1A2 0 2.036 -0.110 0.350 0.078 -0.079

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EEF1A2 Ubiquitylation K179 0.816 _EVSAYIK(gl)K_
EEF1A2 Ubiquitylation K180 0.871 0.816 _EVSAYIKK(gl)_
EEF1A2 Ubiquitylation K392 0.713 _KLEDNPK(gl)SLK_

Background Information for EEF1A2:


Pubmed-EEF1A2 »
Uniprot-EEF1A2 »
Biogrid-EEF1A2 »
ProteomicsDB-EEF1A2 »

Tumorportal-EEF1A2 »
COSMIC-EEF1A2 »
GenomeRNAi-EEF1A2 »
Genecards-EEF1A2


Protein-protein Interactions for EEF1A2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABTB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTNL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf125 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CKS1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTAGE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CXorf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DBF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHX57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EEF1G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOMER1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPB8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1F6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC56 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLLT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait N6AMT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCSTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PITHD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPIAL4G Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC13A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC38A7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1IP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST6GALNAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBXAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR53 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF490 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EEF1A2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Transl_B-barrel IPR009000 0.24
Category members Transl_elong_EF1A_euk/arc IPR004539 0.24
Category members Transl_elong_EFTu/EF1A_C IPR004160 0.01
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members Transl_elong_EF1A/Init_IF2_C IPR009001 0


Protein complexes (CORUM database) featuring EEF1A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EEF1A2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005853 eukaryotic translation elongation factor 1 complex Database 0.6
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0008135 translation factor activity, nucleic acid binding Database 0.53
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0003746 translation elongation factor activity Database 0.08
Category members Disease phenotype Early_infantile_epileptic_encephalopathy_5 Early infantile epileptic encephalopathy 5 Database 0.07
Category members GO Category GO:0010035 response to inorganic substance Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0


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