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Query: EEF2K

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EEF2K 2 6.594 -1.120 2.610

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EEF2K Ubiquitylation K485 1.702 1.119 _VCVEK(gl)WNLLNSSR_
EEF2K Phosphorylation S18 0.197 0.661 _LEGVDGGQS(ph)PR_
EEF2K Phosphorylation S470 0.044 0.565 _KYES(ph)DEDSLGSSGR_
EEF2K Phosphorylation S445 -0.049 _ESENSGDSGYPS(ph)EKRGELDDPEPR_
EEF2K Ubiquitylation K341 2.006 -0.155 _DAVNQNTK(gl)LLQSAK_
EEF2K Ubiquitylation K65 0.734 _YYSNLTK(gl)SER_

Background Information for EEF2K:


Pubmed-EEF2K »
Uniprot-EEF2K »
Biogrid-EEF2K »
ProteomicsDB-EEF2K »

Tumorportal-EEF2K »
COSMIC-EEF2K »
GenomeRNAi-EEF2K »
Genecards-EEF2K


Protein-protein Interactions for EEF2K
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FKBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EEF2K
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members MHCK_EF2_kinase IPR004166 0
Category members Sel1-like IPR006597 0


Protein complexes (CORUM database) featuring EEF2K
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EEF2K
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_724 PID_MTOR_4PATHWAY 0 2
Category members Pathway Pathway_1274 BIOCARTA_EIF_PATHWAY 0 0.78
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0008135 translation factor activity, nucleic acid binding Database 0.53
Category members GO Category GO:0031952 regulation of protein autophosphorylation Database 0.39
Category members Pathway Pathway_983 ST_P38_MAPK_PATHWAY 0 0.34
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_1005 ST_ERK1_ERK2_MAPK_PATHWAY 0 0.06
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_1129 PID_P38_GAMMA_DELTA_PATHWAY 0 0
Category members Pathway Pathway_190 REACTOME_SIGNALING_BY_INSULIN_RECEPTOR 0 0
Category members Pathway Pathway_302 REACTOME_PKB_MEDIATED_EVENTS 0 0
Category members Pathway Pathway_303 REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE 0 0
Category members Pathway Pathway_304 REACTOME_PI3K_CASCADE 0 0
Category members Pathway Pathway_839 REACTOME_MTORC1_MEDIATED_SIGNALLING 0 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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