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BIOCARTA_EIF_PATHWAY
(Pathway_1274)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
EIF3A 4 -2.100 4.390 1.636 -0.539 -0.870 -0.336 -0.006
EEF2K 2 -1.120 2.610
EIF2S2 2 -2.220 4.160 1.238 -0.784 0.387 0.537
EIF2S2 2 -2.220 4.160 -0.289
EEF2 2 1.690 -1.040 0.275 1.260 -0.448 0.479 0.184
EIF4G1 1 -1.660 2.810 0.765
EIF4G1 1 -1.660 2.810 -0.451 -0.932 -0.258 -0.331
EIF2S3 1 0.380 0.280 0.168
EIF2S3 1 0.380 0.280 0.842 -0.253 0.010
EIF4E 1 -2.250 4.200 0.590 0.156
EIF4E 1 -2.250 4.200 0.369
EIF4A2 1 0.070 0.140 0.605 -1.090 0.048 0.029
EIF4A2 1 0.070 0.140 0.070 0.033 0.220 -0.539 -0.195
EIF4A2 1 0.070 0.140 -0.007 -0.156
EIF1 1 -0.290 0.000 -0.543 0.178
EIF4G3 0 -0.870 0.650 -0.609 -0.700
EIF5 0 -0.340 0.160 0.483 0.493 0.323
EIF4G2 0 0.700 0.050 -0.629 -0.963
EIF4G2 0 0.700 0.050 1.131 -0.729 0.052
EIF2S1 0 -0.440 -0.030 0.648 0.346 0.497
EIF4A1 0 1.010 -0.810 0.605 -1.090 0.048 0.029
EIF4A1 0 1.010 -0.810 0.248
EIF1AX 0 0.722 0.019 0.663
EIF6 0 -0.610 0.240
EIF6 0 -0.610 0.240

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
EEF2 Ubiquitylation K42 0.239 1.160 _STLTDSLVCK(gl)AGIIASAR_
EEF2 Phosphorylation T57 0.324 0.971 _FT(ph)DTRKDEQER_
EEF2 Phosphorylation T59 0.490 _AGETRFTDT(ph)R_
EEF2 Ubiquitylation K61 0.879 _FTDTRK(gl)DEQER_
EEF2 Ubiquitylation K152 0.436 0.689 _IK(gl)PVLM(ox)M(ox)NK(gl)M(ox)DR_
EEF2 Ubiquitylation K159 0.607 0.150 _IK(gl)PVLM(ox)M(ox)NK(gl)M(ox)DR_
EEF2 Ubiquitylation K235 1.302 _QFAEMYVAK(gl)FAAK_
EEF2 Ubiquitylation K239 2.313 1.670 _FAAK(gl)GEGQLGPAER_
EEF2 Ubiquitylation K251 1.049 _AK(gl)KVEDMMK_
EEF2 Ubiquitylation K252 2.628 3.073 _K(gl)VEDMMK_
EEF2 Ubiquitylation K272 2.208 1.292 _YFDPANGK(gl)FSK_
EEF2 Ubiquitylation K275 2.553 1.565 _FSK(gl)SATSPEGK_
EEF2 Ubiquitylation K283 -0.183 -0.664 _SATSPEGK(gl)KLPR_
EEF2 Ubiquitylation K314 0.865 0.938 _EETAK(gl)LIEK_
EEF2 Ubiquitylation K407 0.530 1.611 _MVPTSDK(gl)GR_
EEF2 Ubiquitylation K426 0.492 0.658 _VFSGLVSTGLK(gl)VR_
EEF2 Phosphorylation T435 0.294 0.141 _IMGPNYT(ph)PGKK_
EEF2 Ubiquitylation K445 0.079 _EDLYLK(gl)PIQR_
EEF2 Ubiquitylation K498 0.992 0.312 _VMK(gl)FSVSPVVR_
EEF2 Ubiquitylation K512 -1.476 -1.170 _VAVEAK(gl)NPADLPK_
EEF2 Ubiquitylation K525 1.009 _LVEGLK(gl)R_
EEF2 Ubiquitylation K572 -0.752 -0.207 _K(gl)SDPVVSYR_
EEF2 Ubiquitylation K594 0.581 0.785 _ETVSEESNVLCLSK(gl)SPNK_
EEF2K Phosphorylation S18 0.197 0.661 _LEGVDGGQS(ph)PR_
EEF2K Ubiquitylation K65 0.734 _YYSNLTK(gl)SER_
EEF2K Ubiquitylation K341 2.006 -0.155 _DAVNQNTK(gl)LLQSAK_
EEF2K Phosphorylation S445 -0.049 _ESENSGDSGYPS(ph)EKRGELDDPEPR_
EEF2K Phosphorylation S470 0.044 0.565 _KYES(ph)DEDSLGSSGR_
EEF2K Ubiquitylation K485 1.702 1.119 _VCVEK(gl)WNLLNSSR_
EIF1 Phosphorylation S2 -0.495 1.632 _S(ph)AIQNLHS(ph)FDPFADASK_
EIF1 Phosphorylation S9 0.497 1.631 _(ac)SAIQNLHS(ph)FDPFADASK_
EIF1 Ubiquitylation K42 0.075 _K(gl)TLTTVQGIADDYDKK_
EIF1 Ubiquitylation K109 1.332 0.610 _DDQLK(gl)VHGF_
EIF1AX Ubiquitylation K29 0.235 0.769 _ELVFK(gl)EDGQEYAQVIK_
EIF1AX Ubiquitylation K56 0.668 1.126 _LEAM(ox)CFDGVK(gl)R_
EIF1AX Ubiquitylation K88 -0.210 0.111 _DYQDNK(gl)ADVILK_
EIF1AX Ubiquitylation K94 0.441 1.037 _DYQDNKADVILK(gl)YNADEAR_
EIF1AX Ubiquitylation K104 0.257 0.111 _SLK(gl)AYGELPEHAK_
EIF2S1 Ubiquitylation K87 -0.040 _GYIDLSK(gl)R_
EIF2S1 Ubiquitylation K101 -0.331 0.258 _CEDK(gl)FTK_
EIF2S1 Ubiquitylation K106 0.463 0.148 _SK(gl)TVYSILR_
EIF2S1 Ubiquitylation K190 -1.695 _LTPQAVK(gl)IR_
EIF2S1 Ubiquitylation K226 -0.401 -2.300 _AGLNCSTENMPIK(gl)INLIAPPR_
EIF2S2 Phosphorylation S2 0.392 0.407 _(ac)S(ph)GDEM(ox)IFDPTM(ox)SKK_
EIF2S2 Phosphorylation S105 0.614 0.180 _DLKIES(ph)DVQEPTEPEDDLDIMLGNK_
EIF2S2 Phosphorylation T111 0.393 -0.207 _IESDVQEPT(ph)EPEDDLDIMLGNKK_
EIF2S2 Ubiquitylation K190 -1.188 _EK(gl)NPDMVAGEK_
EIF2S2 Ubiquitylation K199 0.815 _EKNPDMVAGEK(gl)R_
EIF2S2 Ubiquitylation K265 1.379 _FQQK(gl)QIENVLR_
EIF2S2 Ubiquitylation K276 4.065 _YIK(gl)EYVTCHTCR_
EIF2S2 Ubiquitylation K293 -0.051 0.495 _SPDTILQK(gl)DTR_
EIF2S2 Ubiquitylation K324 0.924 0.471 _TGFQAVTGK(gl)R_
EIF2S3 Ubiquitylation K59 0.426 0.672 _STVVK(gl)AISGVHTVR_
EIF2S3 Ubiquitylation K70 -0.136 0.775 _FK(gl)NELER_
EIF2S3 Ubiquitylation K80 0.618 _NITIK(gl)LGYANAK_
EIF2S3 Ubiquitylation K87 -0.553 1.040 _LGYANAK(gl)IYK_
EIF2S3 Ubiquitylation K90 -1.279 -0.619 _IYK(gl)LDDPSCPRPECYR_
EIF2S3 Ubiquitylation K121 -1.264 0.000 _SCGSSTPDEFPTDIPGTK(gl)GNFK_
EIF2S3 Ubiquitylation K125 -0.886 1.674 _GNFK(gl)LVR_
EIF2S3 Ubiquitylation K196 -0.225 0.792 _IDLVK(gl)ESQAK_
EIF2S3 Ubiquitylation K275 0.154 _SFDVNKPGCEVDDLK(gl)GGVAGGSILK_
EIF2S3 Ubiquitylation K285 0.689 _GGVAGGSILK(gl)GVLK_
EIF2S3 Ubiquitylation K303 -0.429 0.020 _VGQEIEVRPGIVSK(gl)DSEGK_
EIF2S3 Ubiquitylation K308 -1.136 0.216 _DSEGK(gl)LMCKPIFSK_
EIF2S3 Ubiquitylation K312 -0.523 0.555 _LMCK(gl)PIFSK_
EIF2S3 Ubiquitylation K391 0.111 _LLGVRTEGDKK(gl)_
EIF2S3 Ubiquitylation K421 0.258 1.210 _VSAVK(gl)ADLGK_
EIF2S3 Ubiquitylation K440 0.386 1.041 _IVLTNPVCTEVGEK(gl)IALSR_
EIF2S3 Ubiquitylation K466 -0.588 0.203 _GVTIK(gl)PTVDDD_
EIF3A Ubiquitylation K351 0.570 0.759 _LLDMDGIIVEK(gl)QR_
EIF3A Ubiquitylation K409 0.925 0.382 _VTK(gl)VLNWVR_
EIF3A Ubiquitylation K591 1.447 _EK(gl)EELEQR_
EIF3A Ubiquitylation K603 1.501 1.065 _EAELQK(gl)VR_
EIF3A Ubiquitylation K632 1.585 _ILQEHEQIK(gl)K_
EIF3A Ubiquitylation K651 0.237 _TELGAK(gl)AFK_
EIF3A Ubiquitylation K679 1.837 _QVEQLEK(gl)EKK_
EIF3A Ubiquitylation K694 1.339 _K(gl)IDYFER_
EIF3A Ubiquitylation K711 1.654 _LEEIPLIK(gl)SAYEEQR_
EIF3A Ubiquitylation K775 -0.180 -0.313 _QSVYEEK(gl)LKQFEER_
EIF3A Ubiquitylation K777 1.253 3.661 _LK(gl)QFEER_
EIF3A Ubiquitylation K824 -0.025 _AEEQMLK(gl)ER_
EIF3A Phosphorylation S881 0.249 0.319 _RLGDS(ph)SLSR_
EIF3A Phosphorylation S882 -0.148 0.319 _LGDSS(ph)LSR_
EIF3A Phosphorylation S1336 -0.904 -0.762 _RVPPPALS(ph)R_
EIF4A1 Ubiquitylation K54 0.141 0.814 _GIYAYGFEK(gl)PSAIQQR_
EIF4A1 Ubiquitylation K68 -0.187 0.201 _AILPCIK(gl)GYDVIAQAQSGTGK_
EIF4A1 Ubiquitylation K146 -1.101 -1.263 _AEVQK(gl)LQMEAPHIIVGTPGR_
EIF4A1 Ubiquitylation K174 -0.518 -0.258 _YLSPK(gl)YIK_
EIF4A1 Ubiquitylation K291 -0.226 _VDWLTEK(gl)MHAR_
EIF4A1 Ubiquitylation K309 0.062 -0.357 _DFTVSAMHGDMDQK(gl)ERDVIMR_
EIF4A1 Ubiquitylation K369 0.625 -0.611 _K(gl)GVAINM(ox)VTEEDK(gl)R_
EIF4A1 Ubiquitylation K381 -0.034 0.613 _K(gl)GVAINM(ox)VTEEDK(gl)R_
EIF4A2 Phosphorylation S10 1.817 _(ac)ATTATM(ox)ATS(ph)GSARK_
EIF4A2 Phosphorylation S12 -0.433 0.298 _(ac)ATTATMATSGS(ph)AR_
EIF4A2 Ubiquitylation K54 0.141 0.814 _GIYAYGFEK(gl)PSAIQQR_
EIF4A2 Ubiquitylation K68 -0.187 0.201 _AILPCIK(gl)GYDVIAQAQSGTGK_
EIF4A2 Ubiquitylation K146 -1.101 -1.263 _AEVQK(gl)LQMEAPHIIVGTPGR_
EIF4A2 Phosphorylation T163 0.454 _KLDYGQHVVAGT(ph)PGR_
EIF4A2 Ubiquitylation K174 -0.518 -0.258 _YLSPK(gl)YIK_
EIF4A2 Ubiquitylation K175 0.506 _YLSPK(gl)WIK_
EIF4A2 Ubiquitylation K291 -0.226 _VDWLTEK(gl)MHAR_
EIF4A2 Ubiquitylation K309 0.062 -0.357 _DFTVSAMHGDMDQK(gl)ERDVIMR_
EIF4A2 Ubiquitylation K314 0.119 _EANFTVSSMHGDMPQK(gl)ER_
EIF4A2 Ubiquitylation K321 0.578 0.367 _ESIMK(gl)EFR_
EIF4A2 Ubiquitylation K369 0.625 -0.611 _K(gl)GVAINM(ox)VTEEDK(gl)R_
EIF4A2 Ubiquitylation K374 0.958 _K(gl)GVAINFVK_
EIF4A2 Ubiquitylation K381 -0.034 0.613 _K(gl)GVAINM(ox)VTEEDK(gl)R_
EIF4E Ubiquitylation K147 -0.433 0.065 _WLITLNK(gl)QQR_
EIF4G1 Ubiquitylation K627 -0.658 _SDQWK(gl)PLNLEEK_
EIF4G1 Ubiquitylation K635 -1.721 -1.834 _SDQWKPLNLEEKK(gl)_
EIF4G1 Phosphorylation T672 -1.605 _ANKT(ph)PLRPLDPTR_
EIF4G1 Ubiquitylation K925 0.326 _SLGNIK(gl)FIGELFK_
EIF4G1 Ubiquitylation K975 -0.759 _DLDFEK(gl)AKPR_
EIF4G1 Phosphorylation T1098 -0.123 _IT(ph)KPGSIDSNNQLFAPGGR_
EIF4G1 Phosphorylation S1102 0.238 -0.562 _ITKPGS(ph)IDSNNQLFAPGGR_
EIF4G1 Phosphorylation S1117 -0.554 _ITKPGSIDSNNQLFAPGGRLS(ph)WGK_
EIF4G1 Phosphorylation S1210 0.417 1.061 _S(ph)FSKEVEER_
EIF4G1 Phosphorylation S1212 1.007 0.725 _RSFS(ph)KEVEER_
EIF4G1 Phosphorylation S1234 0.676 1.054 _AAS(ph)LTEDRDR_
EIF4G1 Phosphorylation T1236 1.002 _KAAS(ph)LTEDRDR_
EIF4G1 Phosphorylation S1256 -1.072 -0.563 _REAALPPVS(ph)PLK_
EIF4G1 Phosphorylation S1263 0.713 0.836 _AALS(ph)EEELEKK_
EIF4G2 Ubiquitylation K260 0.068 -1.066 _NVDVYDK(gl)R_
EIF4G2 Ubiquitylation K361 0.871 0.407 _MCSLMLSK(gl)ELPAR_
EIF4G2 Phosphorylation S454 -1.517 _MDRDPLGGLADMFGQMPGS(ph)GIGTGPGVIQDRFSPTMGR_
EIF4G2 Phosphorylation T458 -0.619 -1.448 _DPLGGLADMFGQMPGSGIGT(ph)GPGVIQDRFSPTM(ox)GR_
EIF4G2 Phosphorylation S468 -0.235 -0.781 _FS(ph)PTMGR_
EIF4G2 Phosphorylation T581 -1.576 -0.919 _TQT(ph)PPLGQTPQLGLK_
EIF4G3 Phosphorylation S428 -0.198 -0.408 _SPS(ph)PVLR_
EIF4G3 Phosphorylation S436 1.117 _LVLS(ph)GEKK_
EIF4G3 Phosphorylation S691 -0.438 -0.303 _S(ph)PVPAQIAITVPK_
EIF4G3 Phosphorylation S1352 0.654 0.877 _GGS(ph)SKDLLDNQSQEEQR_
EIF4G3 Phosphorylation S1353 0.803 -0.554 _GGS(ph)SKDLLDNQSQEEQRR_
EIF4G3 Phosphorylation S1605 0.606 0.554 _LDFIESDS(ph)PCSSEALSK_
EIF6 Ubiquitylation K54 -0.119 _CGGSPGAYGGGEACAGVK(gl)SSGSGR_
EIF6 Phosphorylation S235 0.532 _LNEAQPSTIATS(ph)M(ox)RDSLIDSLT_
EIF6 Phosphorylation S239 -0.389 0.417 _LNEAQPSTIATSM(ox)RDS(ph)LIDSLT_


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