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Query: EIF5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF5 0 1.459 -0.340 0.160 0.483 0.493 0.323

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for EIF5:


Pubmed-EIF5 »
Uniprot-EIF5 »
Biogrid-EIF5 »
ProteomicsDB-EIF5 »

Tumorportal-EIF5 »
COSMIC-EIF5 »
GenomeRNAi-EIF5 »
Genecards-EIF5


Protein-protein Interactions for EIF5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC30A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Transl_init_fac_IF2/IF5 IPR002735 0.08
Category members Transl_init_fac_IF2/IF5_N IPR016189 0.08
Category members Transl_init_fac_IF2/IF5_Zn-bd IPR016190 0.08
Category members W2_domain IPR003307 0.04


Protein complexes (CORUM database) featuring EIF5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EIF5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006413 translational initiation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_1274 BIOCARTA_EIF_PATHWAY 0 0.78
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0008135 translation factor activity, nucleic acid binding Database 0.53
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members Pathway Pathway_1174 BIOCARTA_EIF2_PATHWAY 0 0.22
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04


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