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Query: GCN1L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GCN1L1 1 2.739 1.290 -0.930 0.125 -0.510 0.357 0.076 0.016

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GCN1L1 Ubiquitylation K2183 2.095 0.580 _SK(gl)ADYTSHLR_
GCN1L1 Ubiquitylation K12 0.453 0.104 _(ac)AADTQVSETLK(gl)R_
GCN1L1 Ubiquitylation K1679 1.567 -0.083 _TVSAK(gl)ALGAMVK_
GCN1L1 Ubiquitylation K829 0.801 -0.151 _GIKEEVQLTSK(gl)QK_
GCN1L1 Ubiquitylation K1395 -0.248 _K(gl)GAAYGLAGLVK_
GCN1L1 Ubiquitylation K789 0.255 -0.354 _SIIQSAQQDSIKK(gl)_
GCN1L1 Ubiquitylation K695 -0.495 _MK(gl)IDPEAFITR_
GCN1L1 Ubiquitylation K2280 -0.810 _EGVLTGSPEQK(gl)EEAAK_
GCN1L1 Ubiquitylation K308 -0.980 _GLAGHLK(gl)SNSPR_
GCN1L1 Ubiquitylation K1514 -1.429 _TK(gl)AGSVELLGAMAYCAPK_
GCN1L1 Ubiquitylation K788 -0.424 _SIIQSAQQDSIK(gl)K_
GCN1L1 Ubiquitylation K1556 0.235 _LTEVLTDSHVKVQK(gl)_

Background Information for GCN1L1:


Pubmed-GCN1L1 »
Uniprot-GCN1L1 »
Biogrid-GCN1L1 »
ProteomicsDB-GCN1L1 »

Tumorportal-GCN1L1 »
COSMIC-GCN1L1 »
GenomeRNAi-GCN1L1 »
Genecards-GCN1L1


Protein-protein Interactions for GCN1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C4orf3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD274 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL13RA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPY2R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OPRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GCN1L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members HEAT IPR000357 3.83
Category members HEAT_type_2 IPR021133 0.74


Protein complexes (CORUM database) featuring GCN1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1183 CDC5L complex Database 2.07
Category members Corum 1182 CDC5L core complex Database 0.08


Categories featuring GCN1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005840 ribosome Database 12.2
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0008135 translation factor activity, nucleic acid binding Database 0.53
Category members GO Category GO:0006417 regulation of translation Database 0


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