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Query: MTIF2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MTIF2 0 1.697 0.630 -0.750 -0.350 0.783 -0.267 0.657 0.874

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for MTIF2:


Pubmed-MTIF2 »
Uniprot-MTIF2 »
Biogrid-MTIF2 »
ProteomicsDB-MTIF2 »

Tumorportal-MTIF2 »
COSMIC-MTIF2 »
GenomeRNAi-MTIF2 »
Genecards-MTIF2


Protein-protein Interactions for MTIF2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARHGEF26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP5D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BPNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHRS4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DIRAS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ECSIT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXRED1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTPBP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD17B8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LDHAL6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFS7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUDT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDHX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNMTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUCLA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT61B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSFM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUFM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YBEY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MTIF2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Small_GTPase IPR001806 0.65
Category members GTP_binding_domain IPR006073 0.59
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members Transl_B-barrel IPR009000 0.24
Category members SRP_receptor_beta_su IPR019009 0.13
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members TIF_IF2_dom3 IPR023115 0


Protein complexes (CORUM database) featuring MTIF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5233 TNF-alpha/NF-kappa B signaling complex 5 Database 0.29


Categories featuring MTIF2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0008135 translation factor activity, nucleic acid binding Database 0.53
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0001732 formation of translation initiation complex Database 0.11
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04
Category members GO Category GO:0032790 ribosome disassembly Database 0
Category members GO Category GO:0043024 ribosomal small subunit binding Database 0


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