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Results for the Category
regulation of transcription involved in G1/S transition of mitotic cell cycle
(GO:0000083)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PCNA 2 -0.730 0.380 0.679 1.154 0.572 0.718 0.782
BRD4 2 -0.320 0.280 0.080 0.220 0.614 0.191 0.117
NPAT 2 1.890 -0.890 -0.100 -0.144
CDT1 1 -0.050 -0.180
RRM2 1
ORC1 0 1.400 -0.990
ORC1 0 1.400 -0.990 -0.583 -0.836
CDC45 0 -0.450 0.240 0.247 -0.108 0.308 -1.985
CDC6 0 -1.190 2.070
POLA1 0 0.720 -0.610 0.594 0.355 0.027
CCNE1 0 0.460 -0.980
FBXO5 0
RB1 0 1.180 -1.070 0.429 0.755
RB1 0 1.180 -1.070
GFI1 0 0.150 0.340
E2F6 0 -0.120 0.020 -0.460 -0.876 0.160
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501
TYMS 0 -1.190 1.570
E2F4 0 0.930 -0.810
DHFR 0 -1.520 2.470 -0.938 -0.400

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BRD4 Phosphorylation S469 -0.308 -1.544 _MPDEPEEPVVAVS(ph)SPAVPPPTK_
BRD4 Phosphorylation S470 -0.308 -0.758 _MPDEPEEPVVAVSS(ph)PAVPPPTK_
BRD4 Phosphorylation S1083 -1.699 -1.783 _EAPSPLMIHSPQMSQFQSLTHQS(ph)PPQQNVQPK_
BRD4 Phosphorylation S1117 2.833 1.857 _IHS(ph)PIIR_
BRD4 Phosphorylation S1126 1.336 0.890 _SEPFS(ph)PSLRPEPPKHPESIK_
CCNE1 Phosphorylation S100 -0.765 _IIAPS(ph)RGSPLPVLSWANR_
CCNE1 Phosphorylation S103 -0.765 _IIAPS(ph)RGSPLPVLSWANR_
CCNE1 Phosphorylation S387 0.705 -0.922 _AS(ph)PLPSGLLTPPQSGK_
CDC45 Ubiquitylation K514 0.237 -1.244 _SFVCSTK(gl)NRR_
CDC45 Ubiquitylation K560 -0.065 -0.647 _AFEK(gl)AAESTSSR_
CDC6 Ubiquitylation K33 1.448 _NSSDAK(gl)LEPTNVQTVTCSPR_
CDC6 Phosphorylation S45 -0.996 _LEPTNVQTVTCS(ph)PR_
CDC6 Phosphorylation S54 -0.860 _ALPLS(ph)PR_
CDC6 Phosphorylation S106 -0.049 _LVFDNQLTIKS(ph)PSK_
CDC6 Ubiquitylation K221 1.075 _ILQDLKK(gl)_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CDT1 Ubiquitylation K24 -3.025 1.688 _IAPPK(gl)LACR_
CDT1 Phosphorylation T29 -0.527 _T(ph)PSPARPALR_
CDT1 Phosphorylation S73 -1.743 _LRLS(ph)VDEVSSPSTPEAPDIPACPSPGQK_
CDT1 Phosphorylation S93 -2.789 _LSVDEVSSPSTPEAPDIPACPS(ph)PGQK_
CDT1 Ubiquitylation K218 0.676 _SETPTFAK(gl)VQR_
CDT1 Ubiquitylation K259 1.150 _SVPTFK(gl)DGTR_
CDT1 Phosphorylation S316 -0.503 _AFLAS(ph)LSPAMVVPEDQLTR_
CDT1 Phosphorylation S318 -2.552 -0.359 _AFLASLS(ph)PAMVVPEDQLTR_
CDT1 Ubiquitylation K377 3.560 _MEK(gl)ALSQLALR_
CDT1 Phosphorylation S411 -1.380 _PALPATPPATPPAAS(ph)PSALK_
CDT1 Ubiquitylation K522 0.136 _TDTYVK(gl)LDK_
DHFR Ubiquitylation K55 -0.547 _QNLVIMGK(gl)K_
DHFR Ubiquitylation K56 -0.219 _QNLVIMGK(gl)K_
DHFR Ubiquitylation K81 -1.954 _ELK(gl)EPPQGAHFLSR_
DHFR Ubiquitylation K99 -2.021 _SLDDALK(gl)LTEQPELANK_
DHFR Ubiquitylation K133 1.408 _EAM(ox)NHPGHLK(gl)LFVTR_
DHFR Ubiquitylation K158 -1.504 _YK(gl)LLPEYPGVLSDVQEEK_
DHFR Ubiquitylation K174 -2.693 _LLPEYPGVLSDVQEEK(gl)GIK_
E2F4 Phosphorylation T14 -2.100 _(ac)AEAGPQAPPPPGT(ph)PSR_
E2F4 Phosphorylation S16 -2.158 -1.655 _(ac)AEAGPQAPPPPGTPS(ph)R_
FBXO5 Ubiquitylation K113 -0.879 _IVQLETESK(gl)R_
FBXO5 Ubiquitylation K207 -1.407 -0.639 _VVCSTLKK(gl)_
FBXO5 Ubiquitylation K352 0.933 0.734 _LSNQGDQK(gl)GSTYSR_
GFI1 Phosphorylation S68 0.285 0.145 _DRLS(ph)PESQLTEAPDR_
NPAT Phosphorylation S1151 1.822 1.879 _KVS(ph)PTEIVLESFHK_
NPAT Phosphorylation T1153 1.781 _KVSPT(ph)EIVLESFHK_
ORC1 Ubiquitylation K99 -0.379 _FCEVPACK(gl)R_
ORC1 Ubiquitylation K149 0.303 -0.651 _DVVPTNLK(gl)NEK_
ORC1 Ubiquitylation K152 -0.651 _DVVPTNLK(gl)NEK_
PCNA Ubiquitylation K13 0.209 2.207 _LVQGSILK(gl)K_
PCNA Ubiquitylation K14 0.233 2.833 _LVQGSILKK(gl)_
PCNA Ubiquitylation K80 0.570 1.579 _ILK(gl)CAGNEDIITLR_
PCNA Ubiquitylation K164 2.309 2.671 _DLSHIGDAVVISCAK(gl)DGVK_
PCNA Ubiquitylation K168 2.484 2.645 _DLSHIGDAVVISCAKDGVK(gl)_
PCNA Ubiquitylation K248 0.226 0.515 _IADMGHLK(gl)YYLAPK_
POLA1 Phosphorylation S192 -0.049 -0.187 _S(ph)IGASPNPFSVHTATAVPSGK_
POLA1 Phosphorylation S196 -0.374 _RSIGAS(ph)PNPFSVHTATAVPSGK_
POLA1 Ubiquitylation K1120 -0.317 _DTIVENIQK(gl)R_
RB1 Phosphorylation S69 -3.602 -3.397 _TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1 Ubiquitylation K97 -0.546 _LK(gl)IPDHVR_
RB1 Phosphorylation T388 0.005 0.116 _TLQTDSIDSFETQRT(ph)PR_
RB1 Phosphorylation T405 -0.851 -0.901 _KSNLDEEVNVIPPHT(ph)PVR_
RB1 Phosphorylation S820 -0.019 _S(ph)PYKFPSSPLR_
RB1 Ubiquitylation K823 -2.214 _SPYK(gl)FPSSPLR_
RB1 Phosphorylation S827 0.824 0.111 _FPSS(ph)PLR_
RB1 Phosphorylation S839 -0.701 -1.045 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K842 -0.751 _IPGGNIYISPLK(gl)SPYK_
RB1 Phosphorylation S843 -0.701 -0.022 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K846 -2.084 _SPYK(gl)ISEGLPTPTK_
RB1 Phosphorylation T853 0.039 -0.555 _ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1 Ubiquitylation K856 -1.350 _ISEGLPTPTK(gl)MTPR_
RB1 Phosphorylation T858 -0.782 0.564 _ISEGLPT(ph)PTKMT(ph)PR_
RB1 Ubiquitylation K879 -0.187 _FQK(gl)INQMVCNSDR_
RRM2 Phosphorylation S80 -1.483 -1.780 _VPLAPITDPQQLQLS(ph)PLK_
RRM2 Phosphorylation T93 -1.284 -0.534 _GLSLVDKENT(ph)PPALSGTR_
RRM2 Ubiquitylation K106 -0.247 _VLASK(gl)TAR_
RRM2 Ubiquitylation K121 -2.427 -0.884 _TK(gl)AAAPGVEDEPLLR_
RRM2 Ubiquitylation K424 2.394 -0.588 _TNFFEK(gl)R_
TYMS Ubiquitylation K99 -0.992 _GSTNAK(gl)ELSSK_
TYMS Ubiquitylation K104 -0.543 _ELSSK(gl)GVK_
TYMS Ubiquitylation K169 -0.801 -0.836 _VIDTIK(gl)TNPDDRR_


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