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Query: FBXO5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FBXO5 0 1.668

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FBXO5 Ubiquitylation K352 0.933 0.734 _LSNQGDQK(gl)GSTYSR_
FBXO5 Ubiquitylation K207 -1.407 -0.639 _VVCSTLKK(gl)_
FBXO5 Ubiquitylation K113 -0.879 _IVQLETESK(gl)R_

Background Information for FBXO5:





Protein-protein Interactions for FBXO5

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC15 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANAPC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANAPC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC16 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC23 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait SMCHD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANAPC13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FBXO5

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members F-box_dom IPR001810 0


Protein complexes (CORUM database) featuring FBXO5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FBXO5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Database 3.38
Category members GO Category GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Database 3.35
Category members GO Category GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Database 3.26
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members GO Category GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Database 2.59
Category members Pathway Pathway_788 REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE 0 1.91
Category members Pathway Pathway_322 REACTOME_G1_S_TRANSITION 0 1.77
Category members GO Category GO:0007091 metaphase/anaphase transition of mitotic cell cycle Database 1.58
Category members Pathway Pathway_313 REACTOME_MITOTIC_G1_G1_S_PHASES 0 1.45
Category members GO Category GO:0000082 G1/S transition of mitotic cell cycle Database 1.23
Category members Pathway Pathway_811 REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 0 1.14
Category members Pathway Pathway_326 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION 0 0.49
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members Pathway Pathway_332 REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION 0 0.36
Category members GO Category GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle Database 0.34
Category members GO Category GO:0016050 vesicle organization Database 0.31
Category members GO Category GO:0051225 spindle assembly Database 0.25
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0001556 oocyte maturation Database 0
Category members GO Category GO:0007346 regulation of mitotic cell cycle Database 0
Category members GO Category GO:0040020 regulation of meiosis Database 0
Category members GO Category GO:0045835 negative regulation of meiosis Database 0
Category members GO Category GO:0046785 microtubule polymerization Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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