bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
negative regulation of Wnt signaling pathway
(GO:0030178)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
CBY1 1 -1.700 3.270
CHD8 1 -1.310 2.760 -0.896 0.435 0.478 -1.819 -1.191
CHD8 1 -1.310 2.760 -1.168 0.026 0.297
TSC2 1 0.810 -0.710
TSC2 1 0.810 -0.710 -0.715
LZTS2 1 2.900 -0.740 -4.659 1.113
CCND1 1 -1.820 3.470
WWOX 1 2.850 -1.200
GNB2L1 1 1.000 -0.100 0.279 1.704
GNB2L1 1 1.000 -0.100 -0.278 -0.107 -0.424
LRP6 0 0.210 0.050
HMGXB4 0 -0.280 0.860 0.982 0.423
HMGXB4 0 -0.280 0.860
GRB10 0 0.900 -0.860
APC 0 0.810 -0.720 0.008 0.065
APC2 0 0.850 -0.820 0.008 0.065
LRP1 0 -0.360 0.400 1.199 1.016
CTNNBIP1 0 0.180 -0.150
SOX2 0 -0.250 0.870
MED12 0 -0.180 -0.500 -1.501 -0.491
TLE1 0 0.270 0.000 0.116
CSNK1E 0 -0.170 -0.440 0.150 0.527
CSNK1E 0 -0.170 -0.440 1.237 -0.682 -0.148

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APC Phosphorylation S746 0.284 0.140 _DANIMS(ph)PGSSLPSLHVR_
APC Phosphorylation S749 0.276 _YKDANIM(ox)SPGS(ph)SLPSLHVR_
APC Phosphorylation S782 -0.471 -0.446 _ALEAELDAQHLSETFDNIDNLS(ph)PK_
APC Phosphorylation S1044 0.097 0.452 _YSDEQLNSGRQS(ph)PSQNER_
APC Phosphorylation S1046 0.412 1.084 _YSDEQLNSGRQSPS(ph)QNER_
APC Phosphorylation S1362 -0.007 0.328 _AVEFSSGAKS(ph)PSK_
APC Phosphorylation T1440 -1.261 -0.875 _SKT(ph)PPPPPQTAQTK_
APC Phosphorylation T1775 0.099 _KPT(ph)SPVKPIPQNTEYR_
APC Phosphorylation S1776 0.019 0.099 _KPTS(ph)PVKPIPQNTEYR_
APC Phosphorylation S2095 0.363 _DIQRPDSEHGLS(ph)PDSENFDWK_
APC Phosphorylation S2127 -0.031 _AIQEGANSIVSSLHQAAAAACLS(ph)R_
APC Phosphorylation S2260 -0.624 _TPAS(ph)KSPSEGQTATTSPR_
APC Phosphorylation S2262 -0.026 0.240 _TPASKS(ph)PSEGQTATTSPR_
APC Phosphorylation S2451 -0.249 -0.285 _EAPS(ph)PTLR_
APC Phosphorylation S2537 -0.505 _SHSES(ph)PSRLPINR_
APC Phosphorylation S2571 0.693 0.817 _TGS(ph)SSSILSASSESSEK_
APC Phosphorylation S2673 0.326 0.501 _S(ph)GRSPTGNTPPVIDSVSEK_
APC Phosphorylation S2676 -0.478 0.096 _SGRS(ph)PTGNTPPVIDSVSEK_
APC Phosphorylation T2678 -0.028 0.136 _SPT(ph)GNTPPVIDSVSEK_
APC2 Phosphorylation S746 0.284 0.140 _DANIMS(ph)PGSSLPSLHVR_
APC2 Phosphorylation S749 0.276 _YKDANIM(ox)SPGS(ph)SLPSLHVR_
APC2 Phosphorylation S782 -0.471 -0.446 _ALEAELDAQHLSETFDNIDNLS(ph)PK_
APC2 Phosphorylation S1044 0.097 0.452 _YSDEQLNSGRQS(ph)PSQNER_
APC2 Phosphorylation S1046 0.412 1.084 _YSDEQLNSGRQSPS(ph)QNER_
APC2 Phosphorylation S1362 -0.007 0.328 _AVEFSSGAKS(ph)PSK_
APC2 Phosphorylation T1440 -1.261 -0.875 _SKT(ph)PPPPPQTAQTK_
APC2 Phosphorylation T1775 0.099 _KPT(ph)SPVKPIPQNTEYR_
APC2 Phosphorylation S1776 0.019 0.099 _KPTS(ph)PVKPIPQNTEYR_
APC2 Phosphorylation S2095 0.363 _DIQRPDSEHGLS(ph)PDSENFDWK_
APC2 Phosphorylation S2127 -0.031 _AIQEGANSIVSSLHQAAAAACLS(ph)R_
APC2 Phosphorylation S2260 -0.624 _TPAS(ph)KSPSEGQTATTSPR_
APC2 Phosphorylation S2262 -0.026 0.240 _TPASKS(ph)PSEGQTATTSPR_
APC2 Phosphorylation S2451 -0.249 -0.285 _EAPS(ph)PTLR_
APC2 Phosphorylation S2537 -0.505 _SHSES(ph)PSRLPINR_
APC2 Phosphorylation S2571 0.693 0.817 _TGS(ph)SSSILSASSESSEK_
APC2 Phosphorylation S2673 0.326 0.501 _S(ph)GRSPTGNTPPVIDSVSEK_
APC2 Phosphorylation S2676 -0.478 0.096 _SGRS(ph)PTGNTPPVIDSVSEK_
APC2 Phosphorylation T2678 -0.028 0.136 _SPT(ph)GNTPPVIDSVSEK_
CBY1 Phosphorylation S9 -0.597 -0.810 _PFFGNTFS(ph)PK_
CBY1 Phosphorylation S20 0.383 0.563 _SAS(ph)LSNLHSLDR_
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CHD8 Phosphorylation S557 -0.452 _VPVHQHS(ph)PSEPFLEKPVPDM(ox)TQVSGPNAQLVK_
CHD8 Ubiquitylation K1766 0.498 _EQMK(gl)IEAAER_
CHD8 Phosphorylation S1874 -0.088 -0.155 _TPFKDEIDEFANS(ph)PSEDKEESMEIHATGK_
CHD8 Phosphorylation S1978 0.606 0.061 _M(ox)NYM(ox)QNHQAGAPAPSLS(ph)R_
CHD8 Phosphorylation T1993 -1.383 -1.407 _T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK_
CHD8 Phosphorylation S1995 -0.690 -1.351 _TAS(ph)PLPLRPDAPVEK_
CHD8 Phosphorylation S2008 -1.339 -1.407 _T(ph)ASPLPLRPDAPVEKS(ph)PEETATQVPSLESLTLK_
CHD8 Phosphorylation S2046 0.427 0.449 _VS(ph)PSDTTPLVSR_
CHD8 Phosphorylation S2519 -0.083 -0.552 _APGYPSS(ph)PVTTASGTTLR_
CHD8 Phosphorylation S2533 -0.792 _RTS(ph)LSAEDAEVTK_
CHD8 Phosphorylation S2559 -0.345 -0.513 _NIPS(ph)PGQLDPDTR_
CHD8 Phosphorylation S2956 0.383 -0.248 _DGETLEGS(ph)DAEESLDK_
CSNK1E Ubiquitylation K43 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K45 -1.168 _LECVK(gl)TK_
CSNK1E Ubiquitylation K140 -0.969 _DVKPDNFLMGLGK(gl)K_
CSNK1E Ubiquitylation K141 -0.969 -0.720 _DVKPDNFLMGLGKK(gl)_
CSNK1E Phosphorylation S363 -0.662 -0.352 _IQPAGNTS(ph)PR_
CSNK1E Phosphorylation S389 0.394 0.817 _GAPANVS(ph)SSDLTGR_
CTNNBIP1 Ubiquitylation K19 -1.489 _EGAPGKSPEEMYIQQK(gl)VR_
GNB2L1 Ubiquitylation K38 -0.238 0.350 _DK(gl)TIIMWK_
GNB2L1 Ubiquitylation K106 -0.290 _RFVGHTK(gl)DVLSVAFSSDNR_
GNB2L1 Ubiquitylation K130 0.632 _TIK(gl)LWNTLGVCK_
GNB2L1 Ubiquitylation K175 -0.554 -0.015 _LVK(gl)VWNLANCK_
GNB2L1 Ubiquitylation K183 -0.161 -0.282 _VWNLANCK(gl)_
GNB2L1 Ubiquitylation K185 -0.061 -0.249 _VWNLANCKLK(gl)_
GNB2L1 Ubiquitylation K257 -0.288 _YWLCAATGPSIK(gl)_
GNB2L1 Ubiquitylation K271 0.756 -0.007 _IIVDELK(gl)QEVISTSSK_
GRB10 Phosphorylation S104 -0.985 -0.688 _SIQPQVS(ph)PR_
HMGXB4 Phosphorylation S101 0.398 0.441 _S(ph)SPQSTDTAMDLLK_
HMGXB4 Phosphorylation S102 0.689 0.609 _KSS(ph)PQSTDTAMDLLK_
HMGXB4 Phosphorylation S497 0.369 0.453 _ASSVGVLS(ph)PQKK_
HMGXB4 Phosphorylation S502 -0.673 -0.959 _S(ph)PPTTMLLPAS(ph)PAK_
HMGXB4 Phosphorylation S512 -0.673 -0.959 _S(ph)PPTTM(ox)LLPAS(ph)PAK_
LRP1 Ubiquitylation K4527 -0.315 _HSLASTDEK(gl)R_
LRP6 Ubiquitylation K1443 -0.221 _GK(gl)SMISSLSIMGGSSGPPYDR_
LZTS2 Phosphorylation S346 0.117 _EAELQQLRDS(ph)LDENEATMCQAYEER_
LZTS2 Ubiquitylation K401 0.613 _AQQLLQLQVFQLQQEK(gl)R_
LZTS2 Phosphorylation S570 0.586 0.663 _AAAGVGGS(ph)LR_
MED12 Ubiquitylation K429 -0.439 _EIEQQIK(gl)ER_
MED12 Ubiquitylation K531 -0.272 _AMVVAKLLEK(gl)_
MED12 Phosphorylation S635 -1.278 -0.801 _GDLAFGAPGPRPPS(ph)PFDDPADDPEHK_
MED12 Ubiquitylation K1001 -1.092 _VK(gl)NTIYCNVEPSESNMR_
MED12 Ubiquitylation K1661 -1.781 _DVITCEPQGSLIDTK(gl)GNK_
MED12 Ubiquitylation K1682 -0.745 _EGLQVSTK(gl)QK_
MED12 Ubiquitylation K1684 -0.960 _EGLQVSTK(gl)QK_
SOX2 Phosphorylation S251 0.157 -0.109 _SEASSS(ph)PPVVTSSSHSR_
TLE1 Phosphorylation S286 0.242 0.160 _DASSS(ph)PASTASSASSTSLK_
TSC2 Ubiquitylation K3 -1.397 _(ac)AK(gl)PTSKDSGLK_
TSC2 Ubiquitylation K14 -1.297 _DSGLKEK(gl)FK_
TSC2 Ubiquitylation K69 0.051 _MIGQICEVAK(gl)TK_
TSC2 Ubiquitylation K71 -0.157 _MIGQICEVAKTK(gl)_
TSC2 Ubiquitylation K258 -0.278 _ELCEPCWK(gl)LMR_
TSC2 Ubiquitylation K634 1.610 _LGLPNK(gl)DGVVR_
TSC2 Phosphorylation S950 -0.152 -0.529 _STS(ph)LNERPK_
TSC2 Phosphorylation S1064 -0.927 _SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2 Phosphorylation S1248 -0.604 _SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2 Phosphorylation S1329 -0.120 _S(ph)SSSPELQTLQDILGDPGDK_
TSC2 Phosphorylation S1331 -0.262 _SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2 Phosphorylation S1332 -0.063 _SSSS(ph)PELQTLQDILGDPGDK_
TSC2 Phosphorylation S1355 0.174 0.351 _ADVGRLS(ph)PEVK_
TSC2 Phosphorylation S1362 0.859 _S(ph)QSGTLDGESAAWSASGEDSR_
TSC2 Phosphorylation S1364 0.522 0.550 _SQS(ph)GTLDGESAAWSASGEDSR_
TSC2 Phosphorylation T1366 0.137 _SQSGT(ph)LDGESAAWSASGEDSR_
TSC2 Phosphorylation S1396 0.498 _S(ph)PSGLRPR_
TSC2 Phosphorylation S1743 0.596 _RLISS(ph)VEDFTEFV_
WWOX Ubiquitylation K100 -1.048 -0.703 _LAFTVDDNPTK(gl)PTTR_


.

© Copyright Svejstrup Laboratory 2015