bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: CHD7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHD7 0 -0.617 0.220 -0.050 -1.168 0.026 0.297

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHD7 Phosphorylation S1874 -0.088 -0.155 _TPFKDEIDEFANS(ph)PSEDKEESMEIHATGK_
CHD7 Phosphorylation S2956 0.383 -0.248 _DGETLEGS(ph)DAEESLDK_
CHD7 Phosphorylation S557 -0.452 _VPVHQHS(ph)PSEPFLEKPVPDM(ox)TQVSGPNAQLVK_
CHD7 Phosphorylation S2559 -0.345 -0.513 _NIPS(ph)PGQLDPDTR_
CHD7 Phosphorylation S2533 -0.792 _RTS(ph)LSAEDAEVTK_

Background Information for CHD7:


Pubmed-CHD7 »
Uniprot-CHD7 »
Biogrid-CHD7 »
ProteomicsDB-CHD7 »

Tumorportal-CHD7 »
COSMIC-CHD7 »
GenomeRNAi-CHD7 »
Genecards-CHD7


Protein-protein Interactions for CHD7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NES Cat. description Hein, Mann, Cell 2015


Protein Domains in CHD7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SNF2_N IPR000330 3.38
Category members Chromo_domain/shadow IPR000953 2.84
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Chromodomain-like IPR016197 2.29
Category members Chromo_domain IPR023780 1.98
Category members Helicase/UvrB_dom IPR006935 0.78
Category members BRK_domain IPR006576 0


Protein complexes (CORUM database) featuring CHD7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CHD7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0006364 rRNA processing Database 2.47
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0030540 female genitalia development Database 0.44
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0050890 cognition Database 0.11
Category members Pathway Pathway_417 PID_WNT_NONCANONICAL_PATHWAY 0 0.09
Category members GO Category GO:0060324 face development Database 0.08
Category members GO Category GO:0060123 regulation of growth hormone secretion Database 0.08
Category members GO Category GO:0016817 hydrolase activity, acting on acid anhydrides Database 0.06
Category members GO Category GO:0043010 camera-type eye development Database 0.05
Category members Disease phenotype CHARGE_SYNDROME CHARGE SYNDROME Database 0
Category members Disease phenotype Idiopathic_hypogonadotropic_hypogonadism_(IHH) Idiopathic hypogonadotropic hypogonadism (IHH) Database 0
Category members Disease phenotype Kallmann_Syndrome Kallmann Syndrome Database 0
Category members Disease phenotype Normosmic_congenital_hypogonadotropic_hypogonadism Normosmic congenital hypogonadotropic hypogonadism Database 0
Category members Disease phenotype OMENN_SYNDROME OMENN SYNDROME Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001568 blood vessel development Database 0
Category members GO Category GO:0003007 heart morphogenesis Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007417 central nervous system development Database 0
Category members GO Category GO:0007512 adult heart development Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0007626 locomotory behavior Database 0
Category members GO Category GO:0007628 adult walking behavior Database 0
Category members GO Category GO:0008015 blood circulation Database 0
Category members GO Category GO:0021545 cranial nerve development Database 0
Category members GO Category GO:0030217 T cell differentiation Database 0
Category members GO Category GO:0035116 embryonic hindlimb morphogenesis Database 0
Category members GO Category GO:0040018 positive regulation of multicellular organism growth Database 0
Category members GO Category GO:0042471 ear morphogenesis Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0
Category members GO Category GO:0043584 nose development Database 0
Category members GO Category GO:0048752 semicircular canal morphogenesis Database 0
Category members GO Category GO:0048806 genitalia development Database 0
Category members GO Category GO:0048844 artery morphogenesis Database 0
Category members GO Category GO:0060041 retina development in camera-type eye Database 0
Category members GO Category GO:0060173 limb development Database 0


.

© Copyright Svejstrup Laboratory 2015