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REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX
(Pathway_378)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ERCC6 4 -1.310 2.800 5.118 1.227 2.135
ERCC6 4 0.480 0.030 5.118 1.227 2.135
ERCC6 4 -1.310 2.800 0.074 0.258
ERCC6 4 0.480 0.030 0.074 0.258
POLR2E 3 -1.668 0.597 1.782 -1.557 1.254
GTF2H1 3 -0.470 0.340 0.260 2.656 2.859 1.092 0.966
POLR2A 3 -0.397 0.863 1.593 -2.121 0.465
POLR2J 2 -0.950 0.830 0.627 1.720
POLR2J 2 -0.730 0.610 0.627 1.720
POLR2J 2 -0.950 0.830 -0.638
POLR2J 2 -0.730 0.610 -0.638
POLR2J3 2 -1.290 1.980 0.627 1.720
POLR2J3 2 -0.380 0.450 0.627 1.720
POLR2B 2 -0.420 0.060
POLR2B 2 -0.420 0.060 -0.204 1.234 2.104 -1.532 0.478
ERCC8 2 -0.520 0.810 1.603 2.305
XAB2 2 -2.710 5.190 0.220 -0.412 0.280 -1.345 -0.339
ERCC2 2 -0.590 1.060 -0.491 1.066
GTF2H2 2 0.890 -0.020 0.105 2.323 2.292 1.092 0.150
GTF2H2C 2 0.105 2.323 2.292 1.092 0.150
ERCC3 2 -1.110 1.490 2.619 2.418 0.499
POLR2L 2 -1.510 2.550 -0.148 0.893 1.580
POLR2J2 1 0.627 1.720
ERCC1 1 -1.720 3.820
ERCC1 1 -1.460 2.450
POLR2C 1 0.720 -0.840 -1.225 -0.292
POLR2C 1 0.720 -0.840 -0.875 0.495 1.776
ERCC5 1 -2.410 5.420
POLR2D 1 -1.222 0.655 1.981
POLR2H 1 -0.862 1.290 2.109 0.203 0.602
POLR2G 1 -0.180 -0.160 -1.233 1.015 2.091 -1.535 0.430
TCEA1 1 -0.560 0.790 -0.119 0.977 2.240 -0.032 0.136
GTF2H4 1 -1.010 2.070 1.371 2.504
MNAT1 0 -0.030 -0.100 0.666
POLR2F 0 -2.123
POLR2I 0 -2.045
GTF2H3 0 -0.020 0.680 1.408 0.908
CCNH 0 1.480 -0.550
POLR2K 0 0.330 -0.790 -0.751
ERCC4 0 1.257

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CCNH Ubiquitylation K189 0.418 _K(gl)TADDFLNR_
ERCC1 Ubiquitylation K162 -0.634 _LQSLGK(gl)NFALR_
ERCC1 Ubiquitylation K243 -0.245 _VTECLTTVK(gl)SVNK_
ERCC1 Ubiquitylation K281 -1.586 _EDLALCPGLGPQK(gl)AR_
ERCC2 Ubiquitylation K268 5.973 1.957 _CQGNLETLQK(gl)TVLR_
ERCC2 Ubiquitylation K507 -2.034 _GNDQVAISSK(gl)FETR_
ERCC5 Phosphorylation S766 -0.289 -0.748 _LKTEKEPDATPPS(ph)PR_
ERCC5 Phosphorylation S809 -0.115 0.693 _NAPAAVDEGSIS(ph)PR_
ERCC5 Ubiquitylation K858 0.818 1.193 _INSSTENSDEGLK(gl)VR_
ERCC5 Phosphorylation S951 -0.018 -0.048 _ELTPAS(ph)PTCTNSVSK_
ERCC5 Phosphorylation S988 0.598 1.186 _FDSSLLSS(ph)DDETK_
ERCC6 Phosphorylation S158 0.039 0.466 _IIEQLS(ph)PQAATSR_
ERCC6 Phosphorylation S212 -0.295 _IELDHAS(ph)LEEDAEPGPSSLGSMLMPVQETAWEELIR_
ERCC6 Ubiquitylation K255 0.184 -1.007 _TGQMTPFGTQIPQK(gl)QEK_
ERCC6 Ubiquitylation K258 0.830 -1.007 _TGQMTPFGTQIPQKQEK(gl)_
ERCC6 Phosphorylation T303 -1.105 _KAPAPVT(ph)PPAPVQNK_
ERCC6 Ubiquitylation K345 0.454 -0.211 _ALQFQGK(gl)VGLPK_
ERCC6 Ubiquitylation K606 0.305 _VAILHETGSYTHK(gl)K_
ERCC6 Ubiquitylation K607 0.278 _VAILHETGSYTHKK(gl)_
ERCC6 Ubiquitylation K663 -0.597 0.145 _NPNAAVTLACK(gl)QFR_
ERCC6 Ubiquitylation K729 1.490 0.510 _TAYK(gl)CACVLR_
ERCC6 Ubiquitylation K759 -0.019 _MSLSLPDK(gl)NEQVLFCR_
ERCC6 Ubiquitylation K774 0.041 1.536 _LTDEQHK(gl)VYQNFVDSK_
ERCC6 Ubiquitylation K783 0.262 -0.019 _VYQNFVDSK(gl)EVYR_
ERCC6 Ubiquitylation K955 -0.048 -0.623 _K(gl)QVTVYR_
ERCC6 Phosphorylation S1068 0.742 0.512 _KFPASNISVNDATS(ph)SEEKSEAK_
ERCC6 Phosphorylation S1142 0.830 0.891 _TSMPS(ph)GDESIDEK_
ERCC6 Phosphorylation S1146 1.367 0.961 _TSMPSGDES(ph)IDEK_
ERCC6 Ubiquitylation K1156 0.818 -0.034 _LGLSYK(gl)R_
ERCC6 Ubiquitylation K1295 0.149 0.443 _VAQDALK(gl)ALR_
ERCC6 Ubiquitylation K1327 -0.793 0.156 _GISGAPAGK(gl)K_
ERCC6 Ubiquitylation K1328 -0.793 0.232 _GISGAPAGKK(gl)_
ERCC6 Phosphorylation S1345 0.486 0.469 _NSNFSVQHPS(ph)STSPTEK_
ERCC6 Phosphorylation S1346 0.052 0.548 _NSNFSVQHPSS(ph)TSPTEK_
ERCC6 Phosphorylation T1347 0.180 0.745 _NSNFSVQHPSST(ph)SPTEK_
ERCC6 Phosphorylation S1348 0.238 0.374 _NSNFSVQHPSSTS(ph)PTEK_
ERCC6 Ubiquitylation K1352 -1.415 _NSNFSVQHPSSTSPTEK(gl)CQDGIMK_
ERCC6 Ubiquitylation K1359 0.923 _CQDGIMK(gl)K_
ERCC6 Ubiquitylation K1360 2.898 _CQDGIMKK(gl)_
ERCC6 Ubiquitylation K1363 -0.116 -0.707 _EGK(gl)DNVPEHFSGR_
ERCC6 Phosphorylation S1379 0.589 0.418 _AEDADS(ph)SSGPLASSSLLAK_
ERCC6 Ubiquitylation K1392 -0.822 -0.293 _AEDADSSSGPLASSSLLAK(gl)MR_
ERCC6 Ubiquitylation K1457 0.602 1.210 _EILQEFESK(gl)LSASQSCVFR_
ERCC6 Ubiquitylation K1487 -0.363 -0.266 _TSGGEGIWK(gl)LKPEYC_
GTF2H1 Ubiquitylation K240 2.338 _LNTGSK(gl)DLFAECAK_
GTF2H2 Ubiquitylation K42 -0.223 _ATIEDILFKAK(gl)_
GTF2H2 Ubiquitylation K77 -1.015 _TMEDQDLK(gl)PNR_
GTF2H2 Ubiquitylation K116 -1.309 _RAEK(gl)LTELSGNPR_
GTF2H2C Ubiquitylation K42 -0.223 _ATIEDILFKAK(gl)_
GTF2H2C Ubiquitylation K77 -1.015 _TMEDQDLK(gl)PNR_
GTF2H2C Ubiquitylation K116 -1.309 _RAEK(gl)LTELSGNPR_
GTF2H3 Ubiquitylation K28 -0.741 _QALK(gl)ESQFTLSK_
GTF2H3 Ubiquitylation K74 -0.538 _FLYPGK(gl)NGR_
GTF2H3 Ubiquitylation K125 -0.584 -0.425 _SDIK(gl)GQHTETLLAGSLAK_
GTF2H3 Ubiquitylation K152 -0.594 _MNKEVK(gl)DNQEMK_
GTF2H3 Ubiquitylation K300 -1.837 _ISLPPVLKAK(gl)_
GTF2H4 Ubiquitylation K452 -2.338 _LMVVTPAGHSDVK(gl)R_
MNAT1 Phosphorylation S279 0.003 0.225 _AAS(ph)PQDLAGGYTSSLACHR_
POLR2A Ubiquitylation K32 1.006 _VQFGVLSPDELK(gl)R_
POLR2A Ubiquitylation K127 1.428 _IK(gl)DILAK_
POLR2A Ubiquitylation K132 0.487 _IKDILAK(gl)SK_
POLR2A Ubiquitylation K149 1.053 _LTHVYDLCK(gl)GK_
POLR2A Ubiquitylation K226 1.254 _VHEIFK(gl)R_
POLR2A Ubiquitylation K279 0.885 _NQDDLTHK(gl)LADIVK_
POLR2A Ubiquitylation K285 1.235 _LADIVK(gl)INNQLR_
POLR2A Ubiquitylation K417 0.662 _GNSQYPGAK(gl)YIIR_
POLR2A Ubiquitylation K707 1.333 _TYQDIQNTIK(gl)K_
POLR2A Ubiquitylation K710 1.362 1.417 _AK(gl)QDVIEVIEK_
POLR2A Ubiquitylation K751 -0.268 1.477 _DK(gl)TGSSAQK(gl)SLSEYNNFK_
POLR2A Ubiquitylation K758 -0.129 1.511 _DKTGSSAQK(gl)SLSEYNNFK_
POLR2A Ubiquitylation K767 1.702 _SLSEYNNFK(gl)SMVVSGAK_
POLR2A Ubiquitylation K775 1.252 _SMVVSGAK(gl)GSK_
POLR2A Ubiquitylation K812 -0.169 _TLPHFIK(gl)DDYGPESR_
POLR2A Ubiquitylation K976 0.145 0.332 _VIFPTGDSK(gl)VVLPCNLLR_
POLR2A Ubiquitylation K1014 0.766 _VVEGVK(gl)ELSK_
POLR2A Ubiquitylation K1125 4.356 1.173 _LK(gl)ELINISK_
POLR2A Ubiquitylation K1155 3.909 0.506 _AK(gl)DILCR_
POLR2A Ubiquitylation K1350 5.000 0.930 _VLSEK(gl)DVDPVR_
POLR2A Phosphorylation T1840 -1.940 _YT(ph)PTSPSYSPSSPEYTPTSPK_
POLR2A Phosphorylation T1842 -2.070 _YTPT(ph)SPSYS(ph)PSSPEYTPTSPK_
POLR2A Phosphorylation S1843 -1.841 -1.437 _YTPTS(ph)PSYSPSSPEYTPTSPK_
POLR2A Phosphorylation Y1846 -1.758 _YTPTSPSY(ph)SPSSPEYTPTS(ph)PK_
POLR2A Phosphorylation S1847 -1.016 -1.726 _Y(ph)TPTSPSYS(ph)PSSPEYTPT(ph)SPK_
POLR2A Phosphorylation S1849 -2.693 _YTPTSPSY(ph)SPS(ph)SPEYTPTSPK_
POLR2A Phosphorylation S1850 -1.360 -0.983 _YTPTSPSYSPSS(ph)PEYTPTS(ph)PK_
POLR2A Phosphorylation Y1853 -1.665 _YTPTSPSYSPSSPEY(ph)TPT(ph)SPK_
POLR2A Phosphorylation T1856 -1.740 _YTPTSPSYS(ph)PSSPEYTPT(ph)SPK_
POLR2A Phosphorylation S1857 -2.153 -2.282 _YTPTSPSYSPSSPEYTPTS(ph)PK_
POLR2A Phosphorylation T1877 -0.410 _YSPT(ph)SPTYS(ph)PTTPK_
POLR2A Phosphorylation S1878 -1.417 -0.623 _YSPTS(ph)PTYSPTT(ph)PK_
POLR2A Phosphorylation S1882 -0.491 0.086 _YSPTS(ph)PTYS(ph)PTTPK_
POLR2A Phosphorylation T1885 -0.372 -0.103 _YSPTS(ph)PTYSPTT(ph)PK_
POLR2A Phosphorylation S1889 -1.476 _YS(ph)PTSPTYSPTS(ph)PVYTPTSPK_
POLR2A Phosphorylation T1891 -3.041 -2.243 _YSPT(ph)SPTYSPTSPVYTPTSPK_
POLR2A Phosphorylation S1892 -2.675 -2.044 _YSPTS(ph)PTYSPTSPVYTPTSPK_
POLR2A Phosphorylation S1896 -1.174 _YSPTSPTYS(ph)PTSPVYTPT(ph)SPK_
POLR2A Phosphorylation T1898 -1.558 _YSPTS(ph)PTYSPT(ph)SPVYTPTSPK_
POLR2A Phosphorylation S1899 -0.903 -1.110 _YSPTSPTYSPTS(ph)PVYT(ph)PTSPK_
POLR2A Phosphorylation T1903 -0.180 -1.726 _YSPTSPTYSPTS(ph)PVYT(ph)PTSPK_
POLR2A Phosphorylation T1905 -1.328 -1.788 _YSPTSPTYSPTS(ph)PVYTPT(ph)SPK_
POLR2A Phosphorylation S1906 -2.720 -2.245 _YSPTS(ph)PTYSPTSPVYTPTS(ph)PK_
POLR2A Phosphorylation S1910 -1.108 -1.445 _YS(ph)PTSPTYS(ph)PTSPK_
POLR2A Phosphorylation T1912 -1.639 _YSPT(ph)SPTYS(ph)PTSPK_
POLR2A Phosphorylation S1913 -2.778 -1.508 _YSPTS(ph)PTYSPTS(ph)PK_
POLR2A Phosphorylation T1915 -2.612 _YSPTSPT(ph)YSPTSPK_
POLR2A Phosphorylation S1917 -2.286 -1.773 _YSPTS(ph)PTYS(ph)PTSPK_
POLR2A Phosphorylation T1919 -2.218 -1.471 _YSPTS(ph)PTYSPT(ph)SPK_
POLR2A Phosphorylation S1920 -1.088 -1.414 _YSPTS(ph)PTYSPTS(ph)PK_
POLR2B Ubiquitylation K43 0.529 _TVIK(gl)EGEEQLQTQHQK_
POLR2B Ubiquitylation K55 1.247 0.522 _EGEEQLQTQHQK(gl)TFIGK_
POLR2B Ubiquitylation K60 -0.347 _TFIGK(gl)IPIMLR_
POLR2B Ubiquitylation K120 0.324 _K(gl)DSKYAYTGECR_
POLR2B Ubiquitylation K123 0.490 _DSK(gl)YAYTGECR_
POLR2B Ubiquitylation K157 1.882 _GGQGAK(gl)K(gl)SAIGQR_
POLR2B Ubiquitylation K158 1.882 _GGQGAK(gl)K(gl)SAIGQR_
POLR2B Ubiquitylation K249 0.973 _YAK(gl)EVLQK_
POLR2B Ubiquitylation K270 -0.350 _EMLPHVGVSDFCETKK(gl)_
POLR2B Ubiquitylation K366 2.033 0.015 _YSLATGNWGDQK(gl)K_
POLR2B Ubiquitylation K367 2.667 0.205 _YSLATGNWGDQKK(gl)_
POLR2B Ubiquitylation K539 -0.182 -0.025 _ICRPLLIVEK(gl)QK_
POLR2B Ubiquitylation K541 -0.374 -0.025 _ICRPLLIVEK(gl)QK_
POLR2B Ubiquitylation K665 -0.055 _MDTLAHVLYYPQK(gl)PLVTTR_
POLR2B Ubiquitylation K740 -0.513 _GFDQEEVFEK(gl)PTR_
POLR2B Ubiquitylation K843 0.603 -0.748 _IPQIGDK(gl)FASR_
POLR2B Ubiquitylation K851 0.621 _HGQK(gl)GTCGIQYR_
POLR2B Ubiquitylation K902 0.615 -0.938 _VSANK(gl)GEIGDATPFNDAVNVQK_
POLR2B Ubiquitylation K1052 -0.541 _NK(gl)TQISLVR_
POLR2E Ubiquitylation K85 2.361 2.270 _VGIK(gl)TIK_
POLR2E Ubiquitylation K88 -0.032 0.560 _TIK(gl)VYCQR_
POLR2E Ubiquitylation K192 0.061 -0.593 _GQVVK(gl)IIRPSETAGR_
POLR2F Ubiquitylation K59 0.390 0.897 _ITTPYM(ox)TK(gl)YER_
POLR2F Ubiquitylation K101 0.662 _K(gl)IPIIIR_
POLR2G Ubiquitylation K27 -0.304 _YFGPNLLNTVK(gl)QK_
POLR2G Ubiquitylation K29 0.016 _QK(gl)LFTEVEGTCTGK_
POLR2G Ubiquitylation K71 0.320 _GFVLYPVK(gl)YK_
POLR2G Ubiquitylation K73 0.320 _GFVLYPVK(gl)YK_
POLR2G Ubiquitylation K146 0.215 _LK(gl)IVGTR_
POLR2H Ubiquitylation K146 0.110 _VYLLMK(gl)K_
POLR2H Ubiquitylation K147 0.013 -0.168 _VYLLMKK(gl)_
POLR2J Ubiquitylation K23 0.286 0.095 _ITINK(gl)DTK_
POLR2J Ubiquitylation K120 2.108 _VAIK(gl)DKQEGIE_
POLR2J Ubiquitylation K122 1.878 _VAIK(gl)DKQEGIE_
POLR2L Ubiquitylation K67 0.770 0.200 _LLNYAPLEK(gl)_
TCEA1 Phosphorylation T96 0.333 0.133 _KKEPAIT(ph)SQNSPEAR_
TCEA1 Phosphorylation S97 0.484 0.281 _EPAITS(ph)QNSPEAR_
TCEA1 Phosphorylation S100 0.006 0.054 _KKEPAITSQNS(ph)PEAR_
TCEA1 Ubiquitylation K242 0.908 _NLTK(gl)EAIR_
TCEA1 Ubiquitylation K265 0.854 _TGGTQTDLFTCGK(gl)CK_
XAB2 Ubiquitylation K420 -0.458 _VILEK(gl)ATK_
XAB2 Ubiquitylation K423 -0.840 _VILEKATK(gl)_
XAB2 Ubiquitylation K677 -0.811 _FADMECK(gl)LGEIDR_
XAB2 Phosphorylation S851 0.111 1.775 _LEQQSVPAAVFGS(ph)LKED_


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