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Query: XAB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
XAB2 2 4.182 -2.710 5.190 0.220 -0.412 0.280 -1.345 -0.339

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
XAB2 Phosphorylation S851 0.111 1.775 _LEQQSVPAAVFGS(ph)LKED_
XAB2 Ubiquitylation K420 -0.458 _VILEK(gl)ATK_
XAB2 Ubiquitylation K677 -0.811 _FADMECK(gl)LGEIDR_
XAB2 Ubiquitylation K423 -0.840 _VILEKATK(gl)_

Background Information for XAB2:


Pubmed-XAB2 »
Uniprot-XAB2 »
Biogrid-XAB2 »
ProteomicsDB-XAB2 »

Tumorportal-XAB2 »
COSMIC-XAB2 »
GenomeRNAi-XAB2 »
Genecards-XAB2


Protein-protein Interactions for XAB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCAS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait CRNKL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ISY1;RAB43 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFAP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMEK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNW1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC94 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHX8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DVL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1143 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLRG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPIE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in XAB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members HAT IPR003107 0


Protein complexes (CORUM database) featuring XAB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring XAB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members Pathway Pathway_338 REACTOME_DNA_REPAIR 0 8.18
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0006289 nucleotide-excision repair Database 6.65
Category members GO Category GO:0006283 transcription-coupled nucleotide-excision repair Database 6.58
Category members Pathway Pathway_342 REACTOME_NUCLEOTIDE_EXCISION_REPAIR 0 5.83
Category members Pathway Pathway_336 REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER 0 4.6
Category members Pathway Pathway_378 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX 0 3.95
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0001824 blastocyst development Database 0


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