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Query: ECT2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ECT2 0 -0.787 0.620 -0.960 -0.787

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ECT2:


Pubmed-ECT2 »
Uniprot-ECT2 »
Biogrid-ECT2 »
ProteomicsDB-ECT2 »

Tumorportal-ECT2 »
COSMIC-ECT2 »
GenomeRNAi-ECT2 »
Genecards-ECT2


Protein-protein Interactions for ECT2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait ECT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GPSM2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM45 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARIH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ECT2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members BRCT_dom IPR001357 1.59
Category members DH-domain IPR000219 0.05


Protein complexes (CORUM database) featuring ECT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ECT2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0017048 Rho GTPase binding Database 0.69
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0070830 tight junction assembly Database 0.36
Category members GO Category GO:0032467 positive regulation of cytokinesis Database 0.35
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members Pathway Pathway_1172 PID_RHOA_REG_PATHWAY 0 0.09
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members GO Category GO:0045859 regulation of protein kinase activity Database 0.01
Category members GO Category GO:0070301 cellular response to hydrogen peroxide Database 0
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0032147 activation of protein kinase activity Database 0
Category members GO Category GO:0032321 positive regulation of Rho GTPase activity Database 0
Category members GO Category GO:0032862 activation of Rho GTPase activity Database 0
Category members GO Category GO:0032863 activation of Rac GTPase activity Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0042307 positive regulation of protein import into nucleus Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043089 positive regulation of Cdc42 GTPase activity Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0045666 positive regulation of neuron differentiation Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0051988 regulation of attachment of spindle microtubules to kinetochore Database 0
Category members GO Category GO:0071277 cellular response to calcium ion Database 0


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