Results for the Category
regulation of attachment of spindle microtubules to kinetochore
(GO:0051988)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| SPAG5 | 1 | 2.190 | -0.780 | -0.550 | -0.684 | |||
| CDC42 | 0 | -0.170 | 0.490 | -0.597 | -1.527 | -1.013 | ||
| CDC42 | 0 | 1.240 | -0.940 | -0.597 | -1.527 | -1.013 | ||
| ECT2 | 0 | 0.620 | -0.960 | -0.787 | ||||
| NEK2 | 0 | -0.540 | 0.300 | |||||
| RACGAP1 | 0 | 0.180 | 0.230 | -0.308 | -0.006 | |||
| RACGAP1 | 0 | 1.070 | -0.710 | -0.308 | -0.006 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CDC42 | Ubiquitylation | K173 | -1.839 | _DDPSTIEK(gl)LAK_ | |
| CDC42 | Ubiquitylation | K178 | -0.801 | -0.716 | _NK(gl)QKPITPETAEK_ |
| CDC42 | Ubiquitylation | K180 | -1.806 | _QK(gl)PITPETAEK(gl)LAR_ | |
| CDC42 | Ubiquitylation | K189 | -1.082 | _QKPITPETAEK(gl)LAR_ | |
| CDC42 | Ubiquitylation | K198 | 0.550 | 1.159 | _AVK(gl)YVECSALTQK_ |
| CDC42 | Ubiquitylation | K208 | -0.937 | 0.038 | _YVECSALTQK(gl)GLK_ |
| CDC42 | Ubiquitylation | K228 | -2.488 | _NVFDEAILAALEPPEPK(gl)K_ | |
| CDC42 | Ubiquitylation | K229 | -1.254 | _NVFDEAILAALEPPEPKK(gl)_ | |
| NEK2 | Ubiquitylation | K152 | -2.296 | _DLKPANVFLDGK(gl)QNVK_ | |
| NEK2 | Ubiquitylation | K353 | -1.746 | _AENLLK(gl)NYSLLK_ | |
| NEK2 | Ubiquitylation | K359 | -0.192 | _NYSLLK(gl)ER_ | |
| NEK2 | Ubiquitylation | K409 | -0.182 | _SENSESQLTSKSK(gl)_ | |
| RACGAP1 | Ubiquitylation | K53 | 0.960 | _TDHELGK(gl)YK_ | |
| RACGAP1 | Ubiquitylation | K60 | 1.380 | _DLLMK(gl)AETER_ | |
| RACGAP1 | Ubiquitylation | K71 | 0.352 | 0.233 | _SALDVK(gl)LK_ |
| RACGAP1 | Ubiquitylation | K84 | 0.484 | 0.846 | _NQVDVEIK(gl)RR_ |
| RACGAP1 | Ubiquitylation | K95 | -0.492 | _AEADCEK(gl)LER_ | |
| RACGAP1 | Ubiquitylation | K199 | -2.285 | -0.347 | _QFVDGPPGPVK(gl)K_ |
| RACGAP1 | Ubiquitylation | K200 | -0.365 | -0.347 | _QFVDGPPGPVKK(gl)_ |
| RACGAP1 | Phosphorylation | S203 | 1.255 | 0.831 | _S(ph)IGSAVDQGNESIVAK_ |
| RACGAP1 | Ubiquitylation | K292 | -0.427 | _LHDFVSK(gl)TVIKPESCVPCGK_ | |
| RACGAP1 | Ubiquitylation | K305 | -0.770 | _TVIKPESCVPCGK(gl)R_ | |
| RACGAP1 | Phosphorylation | T342 | -1.072 | -0.919 | _DRCPLPCIPTLIGT(ph)PVK_ |
| RACGAP1 | Ubiquitylation | K404 | -0.200 | _VK(gl)TVPLLSK_ | |
| RACGAP1 | Ubiquitylation | K490 | 0.528 | _VAQSPHTK(gl)MDVANLAK_ | |
| RACGAP1 | Phosphorylation | T580 | -0.839 | _VSLLGPVTT(ph)PEHQLLK_ | |
| RACGAP1 | Ubiquitylation | K587 | -0.985 | _VSLLGPVTTPEHQLLK(gl)TPSSSSLSQR_ | |
| RACGAP1 | Phosphorylation | S590 | -0.415 | -0.021 | _TPS(ph)SSSLSQR_ |
| RACGAP1 | Phosphorylation | S591 | -0.217 | _TPSS(ph)SSLSQR_ | |
| RACGAP1 | Ubiquitylation | K604 | 0.953 | _STLTK(gl)NTPR_ | |
| SPAG5 | Phosphorylation | S135 | 0.771 | _TIVLVPS(ph)PLGQQQDM(ox)IFEAR_ | |
| SPAG5 | Ubiquitylation | K672 | -1.461 | _LTVK(gl)SQQALQER_ |
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