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Results for the Category
REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS
(Pathway_194)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ATP6V1H 2 -1.810 2.860 0.325
ATP6V1H 2 -1.810 2.860 -0.409
FYN 1 1.080 -1.100
FYN 1 1.080 -1.100
AP2B1 0 0.890 -0.970
AP2B1 0 0.890 -0.970 -0.267 0.203 0.287 0.311 0.233
AP2S1 0 -0.210 0.500 -0.049 0.539 0.830 0.375
AP1M1 0 -0.550 0.780 -0.171 -0.095
AP1M1 0 -0.550 0.780 0.192
AP1B1 0 -0.890 1.670
AP1B1 0 -0.890 1.670 -0.267 0.203 0.287 0.311 0.233
AP1B1 0 -0.890 1.670 -1.575 -0.671
AP1B1 0 -0.890 1.670 0.931 0.543 0.034 0.611 0.276
RAC1 0 -0.580 1.580 0.486 -0.364 -0.568
ARF1 0 0.020 0.040 0.702 -1.163
AP2M1 0 -1.250 2.200 -0.363 0.794 -0.187 0.544 0.370
AP2M1 0 -1.250 2.200
AP1G1 0 -0.070 -0.460 -0.071 0.366 0.385
PACS1 0 -1.200 1.680
PAK2 0 -0.760 1.040
AP1S2 0 1.190 -0.690 -1.049
LCK 0 -0.490 1.390 0.295 0.576
AP2A2 0 -1.330 2.130 1.006 0.165 0.468 0.244 0.392
AP2A1 0 0.510 -1.060 0.414 0.086 0.168 -0.002 0.179
HLA-A 0 0.790 -0.840

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AP1B1 Ubiquitylation K5 0.232 0.554 _(ac)TDSK(gl)YFTTTK_
AP1B1 Ubiquitylation K12 0.255 _K(gl)GEIFELK_
AP1B1 Ubiquitylation K117 -0.547 _VDK(gl)ITEYLCEPLRK_
AP1B1 Ubiquitylation K131 0.324 -0.027 _CLK(gl)DEDPYVRK_
AP1B1 Ubiquitylation K860 -2.206 _LQSSNIFTVAK(gl)R_
AP1B1 Ubiquitylation K899 -0.222 -0.751 _IQPGNPSCTLSLK(gl)CR_
AP1G1 Ubiquitylation K385 1.119 0.748 _DLDVSIK(gl)R_
AP1G1 Ubiquitylation K595 -0.570 -0.014 _AVEYNALFKK(gl)_
AP1M1 Ubiquitylation K43 -0.691 _(ac)SASAVYVLDLK(gl)GK_
AP1M1 Ubiquitylation K45 -0.691 _(ac)SASAVYVLDLK(gl)GK_
AP1M1 Ubiquitylation K272 -0.542 _SK(gl)SVELEDVK_
AP1M1 Ubiquitylation K280 -0.292 _SVELEDVK(gl)FHQCVR_
AP1M1 Ubiquitylation K369 0.791 0.647 _FK(gl)TTVGSVK_
AP2A1 Phosphorylation S655 -1.574 _DPSSNDINGGM(ox)EPTPSTVSTPS(ph)PSADLLGLR_
AP2A1 Ubiquitylation K880 -0.136 _WK(gl)QLSLPQQEAQK_
AP2A2 Ubiquitylation K6 -0.477 0.972 _PAVSK(gl)GDGMR_
AP2A2 Ubiquitylation K616 -0.123 _ESSILAKLK(gl)_
AP2A2 Ubiquitylation K631 -0.267 -0.317 _KGPSTVTDLEDTK(gl)R_
AP2B1 Ubiquitylation K5 0.145 0.310 _(ac)TDSK(gl)YFTTNK_
AP2B1 Ubiquitylation K12 0.255 _K(gl)GEIFELK_
AP2B1 Ubiquitylation K117 -0.547 _VDK(gl)ITEYLCEPLRK_
AP2B1 Ubiquitylation K131 0.324 -0.027 _CLK(gl)DEDPYVRK_
AP2B1 Ubiquitylation K733 -0.273 _AVWLPAVK(gl)AK_
AP2B1 Ubiquitylation K735 -0.839 -0.273 _AVWLPAVKAK(gl)_
AP2M1 Ubiquitylation K249 0.386 0.460 _IVIEK(gl)QGK_
AP2M1 Ubiquitylation K263 -0.058 -0.236 _SGK(gl)QSIAIDDCTFHQCVR_
AP2M1 Ubiquitylation K281 -0.401 0.214 _LSK(gl)FDSER_
AP2M1 Ubiquitylation K306 -2.014 -0.836 _TTK(gl)DIILPFR_
AP2M1 Ubiquitylation K337 -1.115 _SNFK(gl)PSLLAQK_
AP2M1 Ubiquitylation K364 -1.253 _IPTPLNTSGVQVICMK(gl)GK_
AP2S1 Ubiquitylation K45 -1.058 -0.297 _DAK(gl)HTNFVEFR_
AP2S1 Ubiquitylation K130 -1.793 0.099 _ETSQTK(gl)VLK_
ATP6V1H Ubiquitylation K176 1.541 0.958 _TQLSSQK(gl)LR_
FYN Ubiquitylation K13 0.286 _DKEATK(gl)LTEER_
FYN Phosphorylation S21 0.373 0.731 _DGS(ph)LNQSSGYR_
FYN Ubiquitylation K259 0.921 _LTDLSVK(gl)TK_
FYN Ubiquitylation K261 0.099 _LTDLSVKTK(gl)_
FYN Ubiquitylation K273 6.025 _SLCLEKK(gl)_
FYN Ubiquitylation K275 -0.521 _ESLQLIK(gl)R_
HLA-A Ubiquitylation K92 -0.349 _NVK(gl)AQSQTDRVDLGTLR_
HLA-A Ubiquitylation K168 0.549 _SWTAADMAAQITK(gl)R_
HLA-A Ubiquitylation K346 -0.072 -0.211 _K(gl)GGSYTQAASSDSAQGSDVSLTACK(gl)V_
HLA-A Ubiquitylation K370 0.345 0.434 _K(gl)GGSYTQAASSDSAQGSDVSLTACK(gl)V_
LCK Phosphorylation T37 -0.435 _YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK Ubiquitylation K191 -0.112 0.264 _ESETTK(gl)GAYSLSIR_
LCK Ubiquitylation K235 0.323 _AQFDTLQK(gl)LVK_
LCK Ubiquitylation K259 -1.613 _LTTVCPTVK(gl)PQTQGLAK_
PACS1 Phosphorylation T429 1.102 _DTT(ph)SPMELAALEK_
PACS1 Phosphorylation S430 1.190 _DTTS(ph)PMELAALEK_
PACS1 Phosphorylation S493 0.618 _TDLQGS(ph)ASPSKVEGVHTPR_
PACS1 Phosphorylation S495 -0.220 _TDLQGSAS(ph)PSKVEGVHTPR_
PAK2 Phosphorylation S2 -1.228 -0.902 _(ac)S(ph)DNGELEDKPPAPPVR_
PAK2 Ubiquitylation K136 1.213 _FYDSNTVK(gl)QK_
PAK2 Phosphorylation S141 -0.294 -0.321 _YLS(ph)FTPPEK_
PAK2 Ubiquitylation K370 -0.565 _DIK(gl)SDNVLLGMEGSVK_
RAC1 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC1 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC1 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC1 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC1 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC1 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC1 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC1 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_


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