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Query: PACS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PACS1 0 2.650 -1.200 1.680

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PACS1 Phosphorylation S430 1.190 _DTTS(ph)PMELAALEK_
PACS1 Phosphorylation T429 1.102 _DTT(ph)SPMELAALEK_
PACS1 Phosphorylation S493 0.618 _TDLQGS(ph)ASPSKVEGVHTPR_
PACS1 Phosphorylation S495 -0.220 _TDLQGSAS(ph)PSKVEGVHTPR_

Background Information for PACS1:


Pubmed-PACS1 »
Uniprot-PACS1 »
Biogrid-PACS1 »
ProteomicsDB-PACS1 »

Tumorportal-PACS1 »
COSMIC-PACS1 »
GenomeRNAi-PACS1 »
Genecards-PACS1


Protein-protein Interactions for PACS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IQCF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR37 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PACS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phosphofurin_acidic_CS-1 IPR019381 0


Protein complexes (CORUM database) featuring PACS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1927 PKD2-PACS1 complex Database 0.05
Category members Corum 5165 AP1G1-PACS1-FURIN complex Database 0


Categories featuring PACS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_195 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS 0 1.08
Category members Pathway Pathway_194 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS 0 0.83
Category members GO Category GO:0050690 regulation of defense response to virus by virus Database 0.49
Category members Pathway Pathway_1266 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION 0 0.36
Category members GO Category GO:0000042 protein targeting to Golgi Database 0.2
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0044325 ion channel binding Database 0.03
Category members GO Category GO:0030137 COPI-coated vesicle Database 0


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