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Query: AP1M1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AP1M1 0 2.144 -0.550 0.780 -0.171 -0.095
AP1M1 0 2.144 -0.550 0.780 0.192

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AP1M1 Ubiquitylation K369 0.791 0.647 _FK(gl)TTVGSVK_
AP1M1 Ubiquitylation K280 -0.292 _SVELEDVK(gl)FHQCVR_
AP1M1 Ubiquitylation K43 -0.691 _(ac)SASAVYVLDLK(gl)GK_
AP1M1 Ubiquitylation K45 -0.691 _(ac)SASAVYVLDLK(gl)GK_
AP1M1 Ubiquitylation K272 -0.542 _SK(gl)SVELEDVK_

Background Information for AP1M1:


Pubmed-AP1M1 »
Uniprot-AP1M1 »
Biogrid-AP1M1 »
ProteomicsDB-AP1M1 »

Tumorportal-AP1M1 »
COSMIC-AP1M1 »
GenomeRNAi-AP1M1 »
Genecards-AP1M1


Protein-protein Interactions for AP1M1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AP1S2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP1S2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TLR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AP1M1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Longin-like_dom IPR011012 0.34
Category members AP_mu_sigma_su IPR022775 0.25
Category members Clathrin_mu_C IPR008968 0.02
Category members Clathrin_mu IPR001392 0
Category members MHD IPR028565 0


Protein complexes (CORUM database) featuring AP1M1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 144 Gamma-BAR-AP1 complex Database 0.03
Category members Corum 36 AP1 adaptor complex Database 0


Categories featuring AP1M1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_292 PID_ECADHERIN_NASCENT_AJ_PATHWAY 0 2.74
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members Pathway Pathway_474 REACTOME_MEMBRANE_TRAFFICKING 0 1.14
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members Pathway Pathway_195 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS 0 1.08
Category members Pathway Pathway_475 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING 0 0.98
Category members Pathway Pathway_194 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS 0 0.83
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members Pathway Pathway_520 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS 0 0.78
Category members GO Category GO:0006892 post-Golgi vesicle-mediated transport Database 0.74
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0050690 regulation of defense response to virus by virus Database 0.49
Category members Pathway Pathway_1266 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION 0 0.36
Category members GO Category GO:0030665 clathrin-coated vesicle membrane Database 0.24
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_473 REACTOME_LYSOSOME_VESICLE_BIOGENESIS 0 0.13
Category members GO Category GO:0030131 clathrin adaptor complex Database 0.11
Category members GO Category GO:0032588 trans-Golgi network membrane Database 0.05
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0032438 melanosome organization Database 0
Category members GO Category GO:0035646 endosome to melanosome transport Database 0


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