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Query: VAMP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
VAMP3 0 3.884 -0.800 0.690
VAMP3 0 3.884 -0.800 0.690 0.418

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
VAMP3 Phosphorylation S11 0.474 0.952 _(ac)STGPTAATGS(ph)NR_
VAMP3 Ubiquitylation K54 0.408 0.792 _VNVDK(gl)VLER_
VAMP3 Phosphorylation S58 -0.407 0.612 _ADALQAGAS(ph)QFETSAAK_
VAMP3 Ubiquitylation K61 0.558 0.387 _VLERDQK(gl)LSELDDR_
VAMP3 Phosphorylation S63 0.374 _ADALQAGASQFETS(ph)AAK_
VAMP3 Phosphorylation T9 0.318 -0.040 _(ac)STGPTAAT(ph)GSNR_

Background Information for VAMP3:





Protein-protein Interactions for VAMP3

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TINF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPLX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENPP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR183 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JPH4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIFAP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRIQ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANSC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MICA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RINT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCARB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLCO1B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYPL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM206 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPCN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAC14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in VAMP3

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Synaptobrevin IPR001388 0
Category members Synaptobrevin/VAMP_met/fun IPR016444 0


Protein complexes (CORUM database) featuring VAMP3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 874 SNARE complex (VAMP3, VAMP4, VAMP8, STX6) Database 0.62
Category members Corum 1169 SNARE complex (STX4, VAMP8, VAMP3, SNAP23) Database 0.32
Category members Corum 1874 SNARE complex (SNAP25, VAMP3, VAMP2, NAPB, STX13) Database 0
Category members Corum 875 SNARE complex (VAMP3, VAMP4, STX16) Database 0
Category members Corum 876 SNARE complex (VAMP3, STX6, VTI1A) Database 0


Categories featuring VAMP3

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_1261 KEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT 0 1.52
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0061025 membrane fusion Database 0.93
Category members Pathway Pathway_295 PID_ARF6_TRAFFICKING_PATHWAY 0 0.9
Category members GO Category GO:0006461 protein complex assembly Database 0.57
Category members GO Category GO:0006904 vesicle docking involved in exocytosis Database 0.51
Category members GO Category GO:0031201 SNARE complex Database 0.49
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0043001 Golgi to plasma membrane protein transport Database 0.32
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0042147 retrograde transport, endosome to Golgi Database 0.26
Category members GO Category GO:0034446 substrate adhesion-dependent cell spreading Database 0.26
Category members GO Category GO:0030665 clathrin-coated vesicle membrane Database 0.24
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0030141 secretory granule Database 0.11
Category members GO Category GO:0017075 syntaxin-1 binding Database 0.09
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0000149 SNARE binding Database 0.05
Category members GO Category GO:0001921 positive regulation of receptor recycling Database 0.02
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0017156 calcium ion-dependent exocytosis Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0031410 cytoplasmic vesicle Database 0
Category members GO Category GO:0043229 intracellular organelle Database 0


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