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Query: RAB14

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB14 0 -1.166 0.630 -0.150 0.314 0.321

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB14 Ubiquitylation K193 -0.640 _IYQNIQDGSLDLNAAESGVQHK(gl)PSAPQGGR_
RAB14 Ubiquitylation K171 -1.161 -0.915 _TGENVEDAFLEAAKK(gl)_
RAB14 Ubiquitylation K170 -1.161 _TGENVEDAFLEAAK(gl)K_

Background Information for RAB14:


Pubmed-RAB14 »
Uniprot-RAB14 »
Biogrid-RAB14 »
ProteomicsDB-RAB14 »

Tumorportal-RAB14 »
COSMIC-RAB14 »
GenomeRNAi-RAB14 »
Genecards-RAB14


Protein-protein Interactions for RAB14
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait FLNB Cat. description Hein, Mann, Cell 2015
Category members IP bait GDI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB4B Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC33A1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GDI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB14
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32


Protein complexes (CORUM database) featuring RAB14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAB14
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0046907 intracellular transport Database 3.25
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0030670 phagocytic vesicle membrane Database 0.37
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0008543 fibroblast growth factor receptor signaling pathway Database 0.29
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0006895 Golgi to endosome transport Database 0.25
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0045335 phagocytic vesicle Database 0.16
Category members GO Category GO:0005770 late endosome Database 0.09
Category members GO Category GO:0030140 trans-Golgi network transport vesicle Database 0.03
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0005795 Golgi stack Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007269 neurotransmitter secretion Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0032456 endocytic recycling Database 0
Category members GO Category GO:0032880 regulation of protein localization Database 0
Category members GO Category GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network Database 0


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