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Query: ATP2B2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ATP2B2 0 4.923 1.540 -0.900 0.593 0.487

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ATP2B2 Ubiquitylation K807 0.010 1.083 _QVVAVTGDGTNDGPALKK(gl)_
ATP2B2 Ubiquitylation K365 0.997 _SVLQGK(gl)LTK_
ATP2B2 Phosphorylation S17 0.515 0.902 _NS(ph)LKEANHDGDFGITLAELR_
ATP2B2 Ubiquitylation K64 0.642 0.801 _LK(gl)TSPNEGLSGNPADLER_
ATP2B2 Ubiquitylation K193 -0.102 0.773 _IEQEQK(gl)FTVIR_
ATP2B2 Phosphorylation S1177 0.214 0.537 _S(ph)SIHNFM(ox)THPEFR_
ATP2B2 Phosphorylation S1178 0.214 0.537 _S(ph)SIHNFM(ox)THPEFR_
ATP2B2 Ubiquitylation K921 -0.811 0.202 _NK(gl)PLISR_
ATP2B2 Ubiquitylation K773 -0.186 _SSPTDK(gl)HTLVK_
ATP2B2 Phosphorylation S1193 -0.342 -0.629 _IEDS(ph)EPHIPLIDDTDAEDDAPTKR_
ATP2B2 Ubiquitylation K15 1.343 _(ac)GDMANNSVAYSGVK(gl)NSLK_
ATP2B2 Ubiquitylation K19 1.343 _(ac)GDMANNSVAYSGVK(gl)NSLK_
ATP2B2 Ubiquitylation K48 1.326 _K(gl)IQESYGDVYGICTK_
ATP2B2 Ubiquitylation K62 0.733 _IQESYGDVYGICTK(gl)LK_
ATP2B2 Ubiquitylation K747 1.309 _NEK(gl)GEIEQER_

Background Information for ATP2B2:


Pubmed-ATP2B2 »
Uniprot-ATP2B2 »
Biogrid-ATP2B2 »
ProteomicsDB-ATP2B2 »

Tumorportal-ATP2B2 »
COSMIC-ATP2B2 »
GenomeRNAi-ATP2B2 »
Genecards-ATP2B2


Protein-protein Interactions for ATP2B2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAMTS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATPBD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C12orf49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C6orf72 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD79B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2B6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHRS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDNRB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFNB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENTPD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FZD10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GALNT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR161 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LILRB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUFIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGFR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGIR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAPGEF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCARA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC22A16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC2A5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC45A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPACA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST3GAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAC14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ATP2B2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ATPase_P-typ_Ca-transp_plasma IPR006408 0.66
Category members ATP_Ca_trans_C IPR022141 0.66
Category members ATPase_P-typ_cation-transptr_N IPR004014 0.18
Category members ATPase_P-typ_cation-transptr_C IPR006068 0.18
Category members ATPase_P-typ_cyto_domN IPR023299 0.18
Category members Cation_transp_P_typ_ATPase IPR001757 0.08
Category members ATPase_P-typ_transduc_dom_A IPR008250 0.08
Category members HAD-like_dom IPR023214 0


Protein complexes (CORUM database) featuring ATP2B2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ATP2B2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005388 calcium-transporting ATPase activity Database 1.06
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0050910 detection of mechanical stimulus involved in sensory perception of sound Database 0.7
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_1188 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS 0 0.32
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0046068 cGMP metabolic process Database 0.29
Category members GO Category GO:0070588 calcium ion transmembrane transport Database 0.25
Category members GO Category GO:0021692 cerebellar Purkinje cell layer morphogenesis Database 0.23
Category members GO Category GO:0019829 cation-transporting ATPase activity Database 0.15
Category members GO Category GO:0048167 regulation of synaptic plasticity Database 0.14
Category members GO Category GO:0021549 cerebellum development Database 0.14
Category members Pathway Pathway_233 KEGG_CALCIUM_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0050808 synapse organization Database 0.08
Category members Pathway Pathway_285 REACTOME_PLATELET_HOMEOSTASIS 0 0.08
Category members GO Category GO:0008361 regulation of cell size Database 0.06
Category members GO Category GO:0060088 auditory receptor cell stereocilium organization Database 0.05
Category members GO Category GO:0021707 cerebellar granule cell differentiation Database 0.04
Category members GO Category GO:0050885 neuromuscular process controlling balance Database 0.02
Category members GO Category GO:0042428 serotonin metabolic process Database 0.01
Category members Pathway Pathway_182 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES 0 0
Category members Pathway Pathway_183 REACTOME_ION_CHANNEL_TRANSPORT 0 0
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006812 cation transport Database 0
Category members GO Category GO:0006816 calcium ion transport Database 0
Category members GO Category GO:0006874 cellular calcium ion homeostasis Database 0
Category members GO Category GO:0006996 organelle organization Database 0
Category members GO Category GO:0007595 lactation Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0007626 locomotory behavior Database 0
Category members GO Category GO:0016324 apical plasma membrane Database 0
Category members GO Category GO:0021702 cerebellar Purkinje cell differentiation Database 0
Category members GO Category GO:0030182 neuron differentiation Database 0
Category members GO Category GO:0030899 calcium-dependent ATPase activity Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0
Category members GO Category GO:0040011 locomotion Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048839 inner ear development Database 0
Category members GO Category GO:0051480 cytosolic calcium ion homeostasis Database 0
Category members GO Category GO:0051928 positive regulation of calcium ion transport Database 0
Category members GO Category GO:0060113 inner ear receptor cell differentiation Database 0


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