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Query: ARID5B

This is a cancer-associated gene according to the Broad cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ARID5B 0 1.119 0.580 -0.330

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ARID5B Phosphorylation S264 0.496 0.623 _RDS(ph)FSGVK_

Background Information for ARID5B:


Pubmed-ARID5B »
Uniprot-ARID5B »
Biogrid-ARID5B »
ProteomicsDB-ARID5B »

Tumorportal-ARID5B »
COSMIC-ARID5B »
GenomeRNAi-ARID5B »
Genecards-ARID5B


Protein-protein Interactions for ARID5B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHORDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait KAT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6A Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait YIPF5 Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf87 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HDAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THSD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ARID5B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARID/BRIGHT_DNA-bd IPR001606 0


Protein complexes (CORUM database) featuring ARID5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ARID5B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Human mutations Broad_cancer_genes Broad cancer genes (Lawrence et al., 2014) literature 1.14
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0008585 female gonad development Database 0.64
Category members GO Category GO:0030325 adrenal gland development Database 0.52
Category members GO Category GO:0001889 liver development Database 0.51
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0060021 palate development Database 0.23
Category members Disease phenotype LEUKEMIA_ACUTE_LYMPHOBLASTIC LEUKEMIA ACUTE LYMPHOBLASTIC Database 0.11
Category members GO Category GO:0035264 multicellular organism growth Database 0.04
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0001822 kidney development Database 0
Category members GO Category GO:0006807 nitrogen compound metabolic process Database 0
Category members GO Category GO:0008584 male gonad development Database 0
Category members GO Category GO:0009791 post-embryonic development Database 0
Category members GO Category GO:0010761 fibroblast migration Database 0
Category members GO Category GO:0045444 fat cell differentiation Database 0
Category members GO Category GO:0048008 platelet-derived growth factor receptor signaling pathway Database 0
Category members GO Category GO:0048468 cell development Database 0
Category members GO Category GO:0048644 muscle organ morphogenesis Database 0
Category members GO Category GO:0048705 skeletal system morphogenesis Database 0
Category members GO Category GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0
Category members GO Category GO:0060612 adipose tissue development Database 0
Category members GO Category GO:0060613 fat pad development Database 0


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