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BIOCARTA_PTDINS_PATHWAY
(Pathway_63)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GSK3B 2 1.020 -0.870 -1.128 1.091
GSK3A 2 -1.420 1.510 -1.128 1.091
GSK3A 2 -1.420 1.510
EEA1 1 1.570 -0.620 1.098 0.020 0.177
ARHGEF2 1 -0.650 0.360 -0.121 -0.287 0.319 0.984 0.013
PLCG1 1 -0.170 0.000
PFKL 1 -0.440 0.680 0.869 1.217 0.915
LYN 1 -1.790 3.770
LYN 1 -1.790 3.770
BAD 0 -0.660 1.190
PFKP 0 1.100 -0.660 -0.373 0.027 -0.280 0.822 1.058
PRKCZ 0 -0.290 0.310
JAG1 0 -0.260 0.070
RPS6KB1 0 0.850 -0.600
RAC1 0 -0.580 1.580 0.486 -0.364 -0.568
PDPK1 0 0.050 -0.440
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
ARF1 0 0.020 0.040 0.702 -1.163
RAB5A 0 -0.440 0.910 0.089 -0.362
RAB5A 0 0.080 0.240 0.089 -0.362
PFKM 0 -0.290 -0.020 -0.313
PFKM 0 -0.290 -0.020
AP2M1 0 -1.250 2.200 -0.363 0.794 -0.187 0.544 0.370
AP2M1 0 -1.250 2.200
AP2A1 0 0.510 -1.060 0.414 0.086 0.168 -0.002 0.179

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
AP2A1 Phosphorylation S655 -1.574 _DPSSNDINGGM(ox)EPTPSTVSTPS(ph)PSADLLGLR_
AP2A1 Ubiquitylation K880 -0.136 _WK(gl)QLSLPQQEAQK_
AP2M1 Ubiquitylation K249 0.386 0.460 _IVIEK(gl)QGK_
AP2M1 Ubiquitylation K263 -0.058 -0.236 _SGK(gl)QSIAIDDCTFHQCVR_
AP2M1 Ubiquitylation K281 -0.401 0.214 _LSK(gl)FDSER_
AP2M1 Ubiquitylation K306 -2.014 -0.836 _TTK(gl)DIILPFR_
AP2M1 Ubiquitylation K337 -1.115 _SNFK(gl)PSLLAQK_
AP2M1 Ubiquitylation K364 -1.253 _IPTPLNTSGVQVICMK(gl)GK_
ARHGEF2 Phosphorylation S196 -0.074 0.190 _SVS(ph)TTNIAGHFNDESPLGLR_
ARHGEF2 Phosphorylation S208 -1.192 _SVSTTNIAGHFNDES(ph)PLGLR_
ARHGEF2 Phosphorylation S217 0.850 _ILS(ph)QSTDSLNMR_
ARHGEF2 Phosphorylation S219 0.334 0.620 _ILSQS(ph)TDSLNMR_
ARHGEF2 Ubiquitylation K397 -0.617 _LYK(gl)ELYAR_
ARHGEF2 Phosphorylation S689 2.510 1.206 _SES(ph)LESPR_
ARHGEF2 Phosphorylation S735 -0.212 _EPALPLEPDS(ph)GGNTSPGVTANGEAR_
ARHGEF2 Phosphorylation T739 -0.489 _EPALPLEPDSGGNT(ph)SPGVTANGEAR_
ARHGEF2 Phosphorylation S740 -0.461 -0.375 _EPALPLEPDSGGNTS(ph)PGVTANGEAR_
ARHGEF2 Phosphorylation S930 -0.782 -1.060 _S(ph)LPAGDALYLSFNPPQPSR_
ARHGEF2 Phosphorylation S976 0.649 0.809 _QELGS(ph)PEER_
BAD Phosphorylation S74 -0.904 -0.452 _HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD Phosphorylation S75 -0.914 -0.660 _HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD Phosphorylation S97 0.056 _S(ph)RSAPPNLWAAQR_
BAD Phosphorylation S99 -0.299 0.161 _S(ph)APPNLWAAQR_
BAD Phosphorylation S118 1.277 1.089 _RM(ox)S(ph)DEFVDSFKK_
EEA1 Ubiquitylation K100 0.234 1.002 _QEVQDLQASLK(gl)EEK_
EEA1 Ubiquitylation K103 -0.344 _QEVQDLQASLKEEK(gl)_
EEA1 Phosphorylation S354 1.047 1.214 _LS(ph)ASETSLHR_
EEA1 Ubiquitylation K1029 1.686 _SQETFK(gl)QLQSDFYGR_
EEA1 Ubiquitylation K1162 0.355 _EITNLK(gl)DAK_
EEA1 Ubiquitylation K1178 -1.915 _LELQGK(gl)ADSLK_
EEA1 Ubiquitylation K1225 -1.291 _LHSEIKEK(gl)_
EEA1 Ubiquitylation K1312 -0.851 _LQTK(gl)VLELQR_
GSK3A Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3A Phosphorylation S21 -0.406 _TSS(ph)FAEPGGGGGGGGGGPGGSASGPGGTGGGK_
GSK3A Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3A Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3A Ubiquitylation K148 0.396 _ELVAIK(gl)K_
GSK3A Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3A Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3A Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
JAG1 Ubiquitylation K1142 -0.783 _HGANTVPIKDYENK(gl)_
LYN Ubiquitylation K20 -0.592 _GKDSLSDDGVDLK(gl)TQPVR_
LYN Ubiquitylation K40 0.100 _DPTSNK(gl)QQRPVPESQLLPGQR_
LYN Phosphorylation S104 0.944 0.841 _DSLS(ph)DDGVDLK_
LYN Ubiquitylation K213 0.441 _HYQK(gl)QADGLCR_
LYN Ubiquitylation K477 -0.191 _VENCPDELYDIMK(gl)MCWK_
PDPK1 Phosphorylation S241 0.358 0.361 _ANS(ph)FVGTAQYVSPELLTEK_
PDPK1 Ubiquitylation K257 0.571 -0.234 _ANSFVGTAQYVSPELLTEK(gl)SACK_
PFKL Ubiquitylation K365 -0.860 _AMDDK(gl)RFDEATQLR_
PFKL Ubiquitylation K469 0.001 _GGSMLGTK(gl)R_
PFKL Ubiquitylation K616 0.588 -0.447 _MK(gl)TDIQR_
PFKL Ubiquitylation K677 0.140 -0.035 _NYGTK(gl)LGVK_
PFKL Phosphorylation S775 1.454 1.553 _RTLS(ph)MDKGF_
PFKM Ubiquitylation K178 -0.734 _AAYNLVK(gl)R_
PFKM Ubiquitylation K215 -0.787 -0.246 _AGK(gl)ITDEEATK_
PFKM Ubiquitylation K427 -0.699 _LPLMECVQVTK(gl)DVTK_
PFKM Ubiquitylation K431 -0.696 _DVTK(gl)AMDEK_
PFKP Ubiquitylation K10 -0.552 _(ac)MDADDSRAPK(gl)GSLR_
PFKP Ubiquitylation K109 0.384 -0.125 _LK(gl)AACNLLQR_
PFKP Ubiquitylation K156 0.036 _NGQIDK(gl)EAVQK_
PFKP Phosphorylation S386 0.587 0.694 _S(ph)FAGNLNTYK_
PFKP Ubiquitylation K395 0.244 0.109 _SFAGNLNTYK(gl)R_
PFKP Ubiquitylation K688 0.839 0.281 _NFGTK(gl)ISAR_
PFKP Ubiquitylation K724 -0.448 _FTTDDSICVLGISK(gl)R_
PFKP Ubiquitylation K759 -0.159 _LRPLM(ox)K(gl)ILAK_
PLCG1 Ubiquitylation K300 8.031 _DLK(gl)NMLSQVNYR_
PLCG1 Ubiquitylation K348 -0.219 _SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1 Ubiquitylation K552 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K553 -0.355 _NMAQYFK(gl)K_
PLCG1 Ubiquitylation K1063 0.864 0.355 _LTEGK(gl)IMER_
PLCG1 Phosphorylation S1370 0.475 0.515 _AREGS(ph)FESR_
PRKCZ Phosphorylation T560 -0.884 -1.578 _KQALPPFQPQITDDYGLDNFDTQFTSEPVQLT(ph)PDDEDAIKR_
RAC1 Ubiquitylation K115 -1.745 -0.215 _AK(gl)WYPEVR_
RAC1 Ubiquitylation K142 0.492 _LDLRDDK(gl)DTIEK_
RAC1 Ubiquitylation K152 0.099 -0.292 _K(gl)LTPITYPQGLAMAK_
RAC1 Ubiquitylation K166 -0.981 -0.655 _LTPITYPQGLAMAK(gl)EIGAVK_
RAC1 Ubiquitylation K172 1.026 0.412 _EIGAVK(gl)YLECSALTQR_
RAC1 Ubiquitylation K185 -0.113 0.578 _GLK(gl)TVFDEAIR_
RAC1 Ubiquitylation K202 -1.379 -1.447 _AVLCPPPVK(gl)KR_
RAC1 Ubiquitylation K203 -1.708 -1.447 _AVLCPPPVKK(gl)_
RPS6KB1 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
RPS6KB1 Phosphorylation S447 -0.525 -0.458 _TPVS(ph)PVKFSPGDFWGR_


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