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Query: PFKP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PFKP 0 3.655 1.100 -0.660 -0.373 0.027 -0.280 0.822 1.058

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PFKP Phosphorylation S386 0.587 0.694 _S(ph)FAGNLNTYK_
PFKP Ubiquitylation K688 0.839 0.281 _NFGTK(gl)ISAR_
PFKP Ubiquitylation K395 0.244 0.109 _SFAGNLNTYK(gl)R_
PFKP Ubiquitylation K109 0.384 -0.125 _LK(gl)AACNLLQR_
PFKP Ubiquitylation K724 -0.448 _FTTDDSICVLGISK(gl)R_
PFKP Ubiquitylation K10 -0.552 _(ac)MDADDSRAPK(gl)GSLR_
PFKP Ubiquitylation K156 0.036 _NGQIDK(gl)EAVQK_
PFKP Ubiquitylation K759 -0.159 _LRPLM(ox)K(gl)ILAK_

Background Information for PFKP:


Pubmed-PFKP »
Uniprot-PFKP »
Biogrid-PFKP »
ProteomicsDB-PFKP »

Tumorportal-PFKP »
COSMIC-PFKP »
GenomeRNAi-PFKP »
Genecards-PFKP


Protein-protein Interactions for PFKP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NELL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFKL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFKP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PFKP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phosphofructokinase_dom IPR000023 0.1
Category members 6-phosphofructokinase_euk IPR009161 0.1
Category members Phosphofructokinase IPR022953 0.1


Protein complexes (CORUM database) featuring PFKP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PFKP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_57 REACTOME_GLYCOLYSIS 0 4.41
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members Pathway Pathway_63 BIOCARTA_PTDINS_PATHWAY 0 0.91
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members Pathway Pathway_51 KEGG_PENTOSE_PHOSPHATE_PATHWAY 0 0.11
Category members Pathway Pathway_58 KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 0 0.1
Category members GO Category GO:0003872 6-phosphofructokinase activity Database 0.1
Category members GO Category GO:0005945 6-phosphofructokinase complex Database 0.1
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_64 KEGG_GALACTOSE_METABOLISM 0 0.04
Category members GO Category GO:0006002 fructose 6-phosphate metabolic process Database 0.02
Category members GO Category GO:0046872 metal ion binding Database 0


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