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phosphatidylinositol 3-kinase binding
(GO:0043548)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
INSR 2 -0.850 0.830 1.143 0.785
FYN 1 1.080 -1.100
FYN 1 1.080 -1.100
IGF1R 1 -0.490 0.750 1.476 0.714
CALM2 1 -0.690 0.700 1.911
CALM2 1 -0.690 0.700 0.877 -4.680
CALM3 1 -0.190 0.120 1.911
CALM3 1 -0.190 0.120 0.877 -4.680
CALM1 1 -0.440 0.360 1.911
CALM1 1 -0.440 0.360 0.877 -4.680
TYRO3 0 0.220 -0.340
CORO1A 0 0.430 0.570 -0.555 -0.197 -0.725
PIK3R1 0 1.910 -1.220 -0.441 0.147
ATP1A1 0 0.410 -0.420 0.377 0.914 -1.883 0.083 0.031
IRS1 0
LCK 0 -0.490 1.390 0.295 0.576
IRS2 0 -0.190 -0.130

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ATP1A1 Ubiquitylation K9 0.245 0.226 _DK(gl)YEPAAVSEQGDKK_
ATP1A1 Phosphorylation S16 -0.121 0.100 _DKYEPAAVS(ph)EQGDKK_
ATP1A1 Ubiquitylation K22 0.726 _DKYEPAAVSEQGDKK(gl)_
ATP1A1 Ubiquitylation K24 0.135 _YEPAAVSEQGDKKGK(gl)_
ATP1A1 Ubiquitylation K36 1.089 0.875 _DMDELK(gl)K_
ATP1A1 Ubiquitylation K37 1.220 _DMDELK(gl)KEVSMDDHK_
ATP1A1 Ubiquitylation K45 -0.107 _EVSMDDHK(gl)LSLDELHR_
ATP1A1 Ubiquitylation K54 -1.233 0.206 _K(gl)YGTDLSR_
ATP1A1 Ubiquitylation K156 -1.024 0.552 _SSK(gl)IMESFK_
ATP1A1 Ubiquitylation K162 -0.474 0.225 _IMESFK(gl)NMVPQQALVIR_
ATP1A1 Ubiquitylation K212 -0.693 -0.230 _IISANGCK(gl)VDNSSLTGESEPQTR_
ATP1A1 Ubiquitylation K377 -1.676 -0.190 _NLEAVETLGSTSTICSDK(gl)TGTLTQNR_
ATP1A1 Ubiquitylation K444 -0.592 -0.292 _AVFQANQENLPILK(gl)R_
ATP1A1 Ubiquitylation K468 -0.291 0.462 _CIELCCGSVK(gl)EMR_
ATP1A1 Ubiquitylation K476 1.195 _YAK(gl)IVEIPFNSTNK_
ATP1A1 Ubiquitylation K508 -1.151 _NPNTSEPQHLLVMK(gl)GAPER_
ATP1A1 Ubiquitylation K605 0.393 0.204 _AAVPDAVGK(gl)CR_
ATP1A1 Ubiquitylation K625 -2.291 -0.674 _VIMVTGDHPITAK(gl)AIAK_
ATP1A1 Ubiquitylation K629 0.204 _AIAK(gl)GVGIISEGNETVEDIAAR_
ATP1A1 Ubiquitylation K661 -1.060 -0.037 _DAK(gl)ACVVHGSDLK_
ATP1A1 Ubiquitylation K698 -1.846 -0.336 _TSPQQK(gl)LIIVEGCQR_
ATP1A1 Ubiquitylation K726 -1.405 -0.328 _QGAIVAVTGDGVNDSPALK(gl)K_
ATP1A1 Ubiquitylation K727 -1.257 -0.518 _QGAIVAVTGDGVNDSPALKK(gl)_
ATP1A1 Ubiquitylation K773 0.165 _LIFDNLK(gl)K_
ATP1A1 Ubiquitylation K840 -1.467 -0.964 _NPK(gl)TDKLVNER_
ATP1A1 Ubiquitylation K843 0.143 _TDK(gl)LVNER_
ATP1A1 Ubiquitylation K950 0.029 _NSVFQQGMK(gl)NK_
ATP1A1 Ubiquitylation K952 -1.917 0.295 _NSVFQQGMKNK(gl)_
CALM1 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM1 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM2 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM2 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM3 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM3 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
FYN Ubiquitylation K13 0.286 _DKEATK(gl)LTEER_
FYN Phosphorylation S21 0.373 0.731 _DGS(ph)LNQSSGYR_
FYN Ubiquitylation K259 0.921 _LTDLSVK(gl)TK_
FYN Ubiquitylation K261 0.099 _LTDLSVKTK(gl)_
FYN Ubiquitylation K273 6.025 _SLCLEKK(gl)_
FYN Ubiquitylation K275 -0.521 _ESLQLIK(gl)R_
IGF1R Ubiquitylation K47 1.146 _NDYQQLK(gl)R_
IGF1R Ubiquitylation K1033 5.779 _VAIK(gl)TVNEAASMR_
IGF1R Ubiquitylation K1168 0.191 _K(gl)GGKGLLPVR_
IGF1R Ubiquitylation K1171 0.232 _GGK(gl)GLLPVR_
INSR Ubiquitylation K1022 -0.603 _EK(gl)ITLLR_
INSR Ubiquitylation K1047 0.305 0.711 _DIIK(gl)GEAETR_
INSR Ubiquitylation K1057 0.482 0.484 _VAVK(gl)TVNESASLR_
INSR Ubiquitylation K1352 1.606 2.754 _DGGSSLGFK(gl)R_
IRS1 Phosphorylation S1101 -0.078 _HSS(ph)ETFSSTPSATR_
IRS2 Phosphorylation S308 -0.079 -0.510 _SKS(ph)QSSGSSATHPISVPGAR_
IRS2 Phosphorylation T365 0.641 0.852 _T(ph)ASEGDGGAAAGAAAAGAR_
IRS2 Phosphorylation S367 0.757 0.612 _TAS(ph)EGDGGAAAGAAAAGAR_
IRS2 Phosphorylation S393 -1.580 -1.221 _PVSVAGSPLS(ph)PGPVR_
IRS2 Phosphorylation S520 0.359 -1.006 _S(ph)NTPESIAETPPAR_
IRS2 Phosphorylation T522 -1.103 -0.770 _SNT(ph)PESIAETPPAR_
IRS2 Phosphorylation T529 0.230 0.164 _S(ph)NTPESIAET(ph)PPAR_
IRS2 Phosphorylation S562 -0.026 0.439 _RVS(ph)GDAAQDLDR_
IRS2 Phosphorylation S579 0.542 0.362 _RTYS(ph)LTTPAR_
IRS2 Phosphorylation S621 -0.190 _LCPSCPAS(ph)SPK_
IRS2 Phosphorylation S622 -0.195 _LCPSCPASS(ph)PK_
IRS2 Phosphorylation S681 0.409 _SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2 Phosphorylation S732 -1.089 _AS(ph)SPAESSPEDSGYM(ox)R_
IRS2 Phosphorylation S733 -1.027 0.522 _ASS(ph)PAESSPEDSGYM(ox)R_
IRS2 Phosphorylation S738 0.522 _ASS(ph)PAESS(ph)PEDSGYMR_
IRS2 Phosphorylation S917 -0.592 -1.025 _S(ph)PGEYINIDFGEPGAR_
IRS2 Phosphorylation S1164 -0.499 _HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2 Phosphorylation S1178 0.766 0.277 _HNSAS(ph)VENVSLR_
IRS2 Phosphorylation T1204 -0.454 _SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2 Phosphorylation S1205 -0.291 _SSEGGVGVGPGGGDEPPTS(ph)PR_
LCK Phosphorylation T37 -0.435 _YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK Ubiquitylation K191 -0.112 0.264 _ESETTK(gl)GAYSLSIR_
LCK Ubiquitylation K235 0.323 _AQFDTLQK(gl)LVK_
LCK Ubiquitylation K259 -1.613 _LTTVCPTVK(gl)PQTQGLAK_
TYRO3 Phosphorylation S930 0.766 -0.051 _YILTPGGLAEQPGQAEHQPES(ph)PLNETQR_


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