bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
insulin receptor binding
(GO:0005158)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PHIP 2 0.650 -0.230 0.434 0.305
TLN1 1 -0.130 0.000 0.807 0.246 0.137
IGF1R 1 -0.490 0.750 1.476 0.714
SORBS1 0 0.660 -0.330
GRB10 0 0.900 -0.860
IRS4 0 -0.240 -0.060 -0.868 -1.279 -1.308 -0.107 0.122
PDPK1 0 0.050 -0.440
PIK3R1 0 1.910 -1.220 -0.441 0.147
IRS1 0
TLN2 0 -0.680 1.130
PTPN11 0 -0.210 -0.400 0.644 1.053 0.451
IRS2 0 -0.190 -0.130
PTPN1 0 -0.150 0.310 1.066 0.459 0.251 0.322 0.379
ENPP1 0 0.220 -0.270 -0.295 1.478 0.914

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
GRB10 Phosphorylation S104 -0.985 -0.688 _SIQPQVS(ph)PR_
IGF1R Ubiquitylation K47 1.146 _NDYQQLK(gl)R_
IGF1R Ubiquitylation K1033 5.779 _VAIK(gl)TVNEAASMR_
IGF1R Ubiquitylation K1168 0.191 _K(gl)GGKGLLPVR_
IGF1R Ubiquitylation K1171 0.232 _GGK(gl)GLLPVR_
IRS1 Phosphorylation S1101 -0.078 _HSS(ph)ETFSSTPSATR_
IRS2 Phosphorylation S308 -0.079 -0.510 _SKS(ph)QSSGSSATHPISVPGAR_
IRS2 Phosphorylation T365 0.641 0.852 _T(ph)ASEGDGGAAAGAAAAGAR_
IRS2 Phosphorylation S367 0.757 0.612 _TAS(ph)EGDGGAAAGAAAAGAR_
IRS2 Phosphorylation S393 -1.580 -1.221 _PVSVAGSPLS(ph)PGPVR_
IRS2 Phosphorylation S520 0.359 -1.006 _S(ph)NTPESIAETPPAR_
IRS2 Phosphorylation T522 -1.103 -0.770 _SNT(ph)PESIAETPPAR_
IRS2 Phosphorylation T529 0.230 0.164 _S(ph)NTPESIAET(ph)PPAR_
IRS2 Phosphorylation S562 -0.026 0.439 _RVS(ph)GDAAQDLDR_
IRS2 Phosphorylation S579 0.542 0.362 _RTYS(ph)LTTPAR_
IRS2 Phosphorylation S621 -0.190 _LCPSCPAS(ph)SPK_
IRS2 Phosphorylation S622 -0.195 _LCPSCPASS(ph)PK_
IRS2 Phosphorylation S681 0.409 _SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2 Phosphorylation S732 -1.089 _AS(ph)SPAESSPEDSGYM(ox)R_
IRS2 Phosphorylation S733 -1.027 0.522 _ASS(ph)PAESSPEDSGYM(ox)R_
IRS2 Phosphorylation S738 0.522 _ASS(ph)PAESS(ph)PEDSGYMR_
IRS2 Phosphorylation S917 -0.592 -1.025 _S(ph)PGEYINIDFGEPGAR_
IRS2 Phosphorylation S1164 -0.499 _HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2 Phosphorylation S1178 0.766 0.277 _HNSAS(ph)VENVSLR_
IRS2 Phosphorylation T1204 -0.454 _SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2 Phosphorylation S1205 -0.291 _SSEGGVGVGPGGGDEPPTS(ph)PR_
IRS4 Phosphorylation S64 -0.090 -0.062 _S(ph)DSESEEEDLPVGEEVCK_
IRS4 Phosphorylation S66 -0.354 -0.098 _SDS(ph)ESEEEDLPVGEEVCK_
IRS4 Ubiquitylation K99 -1.384 _YFVLK(gl)LETADAPAR_
IRS4 Ubiquitylation K202 -0.581 -0.941 _LILESK(gl)R_
IRS4 Ubiquitylation K240 -0.370 -0.760 _DVWQVIVK(gl)PR_
IRS4 Ubiquitylation K248 -0.351 -0.699 _K(gl)ELSGVFR_
IRS4 Phosphorylation S409 -0.928 -0.559 _FVTPSEPVAHS(ph)R_
IRS4 Phosphorylation S427 -0.406 0.053 _AVS(ph)VPASFFR_
IRS4 Phosphorylation S439 -1.003 -1.061 _RLAPS(ph)PARPR_
IRS4 Phosphorylation S457 0.337 _LS(ph)SEVSGSGSGNFGEEGNPQGK_
IRS4 Phosphorylation S458 0.236 _LSS(ph)EVSGSGSGNFGEEGNPQGK_
IRS4 Ubiquitylation K618 0.019 0.005 _SYFGK(gl)LTQSK_
IRS4 Ubiquitylation K674 -0.511 -0.585 _EVK(gl)DAEIPEGAAR_
IRS4 Phosphorylation Y743 -0.204 0.833 _GY(ph)MMMFPR_
IRS4 Phosphorylation S751 -1.810 -1.680 _VS(ph)PPPAPS(ph)PPK_
IRS4 Phosphorylation S757 -2.068 _VS(ph)PPPAPS(ph)PPK_
IRS4 Phosphorylation T764 -0.886 _APDT(ph)NKEDDSKDNDSESDYMFMAPGAGAIPK_
IRS4 Phosphorylation S775 -0.869 _APDTNKEDDSKDNDS(ph)ESDYMFMAPGAGAIPK_
IRS4 Phosphorylation S777 -0.884 -1.011 _APDTNKEDDSKDNDSES(ph)DYMFMAPGAGAIPK_
IRS4 Phosphorylation Y779 -0.702 -0.231 _APDTNKEDDSKDNDSESDY(ph)MFMAPGAGAIPK_
IRS4 Phosphorylation S804 -0.814 -0.440 _S(ph)WSSYFSLPNPFR_
IRS4 Phosphorylation S810 -1.350 _SWSSYFS(ph)LPNPFR_
IRS4 Phosphorylation S817 -1.106 -1.146 _S(ph)SPLGQNDNSEYVPM(ox)LPGK_
IRS4 Phosphorylation S818 -1.196 -1.146 _S(ph)SPLGQNDNSEYVPM(ox)LPGK_
IRS4 Phosphorylation S826 -0.663 -0.805 _SSPLGQNDNS(ph)EYVPM(ox)LPGK_
IRS4 Ubiquitylation K835 -1.658 -1.572 _SSPLGQNDNSEYVPM(ox)LPGK(gl)FLGR_
IRS4 Phosphorylation S872 -2.103 _PGDGGS(ph)PSKPSDHEPPK_
IRS4 Ubiquitylation K897 -0.308 -0.294 _LSFITK(gl)GYK_
IRS4 Phosphorylation Y921 0.195 -0.259 _EADSSSDY(ph)VNM(ox)DFTK_
IRS4 Ubiquitylation K928 -0.946 -1.115 _EADSSSDYVNMDFTK(gl)R_
IRS4 Phosphorylation S931 -0.413 -1.058 _RES(ph)NTPAPSTQGLPDSWGIIAEPR_
IRS4 Phosphorylation T933 -1.405 _RESNT(ph)PAPSTQGLPDSWGIIAEPR_
IRS4 Phosphorylation S1061 0.641 0.325 _IYVVDPFSECCM(ox)DISLS(ph)PSR_
IRS4 Phosphorylation S1091 -0.218 -0.449 _SQS(ph)FFAAAR_
IRS4 Phosphorylation S1107 -0.374 -0.244 _AAVSAFPTDS(ph)LER_
IRS4 Phosphorylation S1231 -1.675 _VPRPPEREDS(ph)DNDDDTHVR_
IRS4 Phosphorylation S1252 -0.763 _RDNQFDS(ph)PKR_
IRS4 Ubiquitylation K1254 -2.066 -1.156 _RDNQFDSPK(gl)R_
PDPK1 Phosphorylation S241 0.358 0.361 _ANS(ph)FVGTAQYVSPELLTEK_
PDPK1 Ubiquitylation K257 0.571 -0.234 _ANSFVGTAQYVSPELLTEK(gl)SACK_
PHIP Ubiquitylation K6 1.214 _K(gl)GLSELR_
PHIP Ubiquitylation K65 0.460 _TYQNLVK(gl)YYR_
PHIP Phosphorylation S674 0.709 0.567 _LSRGS(ph)ISSTSEVHSPPNVGLR_
PHIP Ubiquitylation K767 0.459 _ENK(gl)IPTVSK_
PHIP Phosphorylation S911 0.029 -0.103 _VNEEKDGPIS(ph)PKK_
PHIP Ubiquitylation K1005 0.642 _EQELMK(gl)IVGIK_
PHIP Ubiquitylation K1032 -0.023 _LAFLDPDTGK(gl)LTGGSFTMK_
PHIP Ubiquitylation K1062 1.216 0.801 _QQFDDAK(gl)YRR_
PHIP Phosphorylation S1315 2.743 1.429 _AQS(ph)YDIQAWKK_
PHIP Ubiquitylation K1383 -0.669 _ETLEAGNYESPMELCK(gl)DVR_
PHIP Phosphorylation S1525 -0.688 _VVVDPVVTEQPSTSS(ph)AAK_
PHIP Ubiquitylation K1528 -0.207 _VVVDPVVTEQPSTSSAAK(gl)TFITK_
PHIP Ubiquitylation K1533 1.039 _TFITK(gl)ANASAIPGK_
PHIP Phosphorylation S1560 -0.176 0.420 _ALNTLSS(ph)PGQSSFSHGTR_
PHIP Ubiquitylation K1602 1.984 _ASTLSK(gl)SSAVIEQGDCK_
PHIP Phosphorylation S1651 -0.008 _VEVNTNS(ph)GEIIHK_
PHIP Phosphorylation S1783 0.754 0.729 _TAFYNEDDS(ph)EEEQR_
PHIP Ubiquitylation K1815 1.427 0.364 _AK(gl)ANLIGW_
PTPN1 Phosphorylation S352 0.032 _GS(ph)PLNAAPYGIESMSQDTEVR_
PTPN1 Phosphorylation S365 -0.247 0.956 _GSPLNAAPYGIESMS(ph)QDTEVR_
PTPN1 Phosphorylation S378 1.462 1.262 _VVGGS(ph)LR_
PTPN11 Ubiquitylation K124 0.562 _EAEK(gl)LLTEK_
SORBS1 Phosphorylation S57 -0.823 0.018 _ETPSSSPAS(ph)PQETR_
SORBS1 Phosphorylation S548 -0.502 -0.518 _RVGEQDSAPTQEKPTS(ph)PGK_
TLN1 Ubiquitylation K334 -0.489 0.561 _LLGITK(gl)ECVM(ox)R_
TLN1 Phosphorylation S423 0.105 _DHFGLEGDEESTMLEDS(ph)VSPKK_
TLN1 Phosphorylation S425 -0.366 -0.322 _DHFGLEGDEESTMLEDSVS(ph)PKK_
TLN1 Ubiquitylation K869 -0.260 _ILADATAK(gl)MVEAAK_
TLN1 Ubiquitylation K1541 0.365 2.311 _EVANSTANLVK(gl)TIK_
TLN1 Ubiquitylation K2021 0.309 0.479 _EGILK(gl)TAK_
TLN2 Phosphorylation T1843 -0.647 _LDEGT(ph)PPEPK_


.

© Copyright Svejstrup Laboratory 2015