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Query: PHIP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHIP 2 7.697 0.650 -0.230 0.434 0.305

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHIP Phosphorylation S1315 2.743 1.429 _AQS(ph)YDIQAWKK_
PHIP Ubiquitylation K1062 1.216 0.801 _QQFDDAK(gl)YRR_
PHIP Phosphorylation S1783 0.754 0.729 _TAFYNEDDS(ph)EEEQR_
PHIP Phosphorylation S674 0.709 0.567 _LSRGS(ph)ISSTSEVHSPPNVGLR_
PHIP Phosphorylation S1560 -0.176 0.420 _ALNTLSS(ph)PGQSSFSHGTR_
PHIP Ubiquitylation K1815 1.427 0.364 _AK(gl)ANLIGW_
PHIP Phosphorylation S1651 -0.008 _VEVNTNS(ph)GEIIHK_
PHIP Phosphorylation S911 0.029 -0.103 _VNEEKDGPIS(ph)PKK_
PHIP Phosphorylation S1525 -0.688 _VVVDPVVTEQPSTSS(ph)AAK_
PHIP Ubiquitylation K6 1.214 _K(gl)GLSELR_
PHIP Ubiquitylation K65 0.460 _TYQNLVK(gl)YYR_
PHIP Ubiquitylation K767 0.459 _ENK(gl)IPTVSK_
PHIP Ubiquitylation K1005 0.642 _EQELMK(gl)IVGIK_
PHIP Ubiquitylation K1032 -0.023 _LAFLDPDTGK(gl)LTGGSFTMK_
PHIP Ubiquitylation K1383 -0.669 _ETLEAGNYESPMELCK(gl)DVR_
PHIP Ubiquitylation K1528 -0.207 _VVVDPVVTEQPSTSSAAK(gl)TFITK_
PHIP Ubiquitylation K1533 1.039 _TFITK(gl)ANASAIPGK_
PHIP Ubiquitylation K1602 1.984 _ASTLSK(gl)SSAVIEQGDCK_

Background Information for PHIP:


Pubmed-PHIP »
Uniprot-PHIP »
Biogrid-PHIP »
ProteomicsDB-PHIP »

Tumorportal-PHIP »
COSMIC-PHIP »
GenomeRNAi-PHIP »
Genecards-PHIP


Protein-protein Interactions for PHIP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATRX Cat. description Hein, Mann, Cell 2015
Category members IP bait BRWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHAF1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4A Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL4B Cat. description Hein, Mann, Cell 2015
Category members IP bait EGR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait ORC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMPO Cat. description Hein, Mann, Cell 2015


Protein Domains in PHIP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members WD40_repeat_dom IPR017986 1.39
Category members Quinonprotein_ADH-like_supfam IPR011047 0.56
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring PHIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PHIP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006606 protein import into nucleus Database 1.81
Category members GO Category GO:0070577 histone acetyl-lysine binding Database 0.88
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0001932 regulation of protein phosphorylation Database 0.04
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0033138 positive regulation of peptidyl-serine phosphorylation Database 0.03
Category members GO Category GO:0005158 insulin receptor binding Database 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0010800 positive regulation of peptidyl-threonine phosphorylation Database 0
Category members GO Category GO:0022604 regulation of cell morphogenesis Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway Database 0
Category members GO Category GO:0045840 positive regulation of mitosis Database 0


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