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Query: SORBS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SORBS1 0 -0.484 0.660 -0.330

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SORBS1 Phosphorylation S57 -0.823 0.018 _ETPSSSPAS(ph)PQETR_
SORBS1 Phosphorylation S548 -0.502 -0.518 _RVGEQDSAPTQEKPTS(ph)PGK_

Background Information for SORBS1:


Pubmed-SORBS1 »
Uniprot-SORBS1 »
Biogrid-SORBS1 »
ProteomicsDB-SORBS1 »

Tumorportal-SORBS1 »
COSMIC-SORBS1 »
GenomeRNAi-SORBS1 »
Genecards-SORBS1


Protein-protein Interactions for SORBS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait SIDT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TGS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TOR1AIP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB2 Cat. description Hein, Mann, Cell 2015


Protein Domains in SORBS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members Sorb IPR003127 0


Protein complexes (CORUM database) featuring SORBS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SORBS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015758 glucose transport Database 2.09
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members GO Category GO:0005915 zonula adherens Database 0.93
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members Pathway Pathway_509 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES 0 0.62
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0008286 insulin receptor signaling pathway Database 0.2
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members GO Category GO:0048041 focal adhesion assembly Database 0.1
Category members GO Category GO:0007015 actin filament organization Database 0.08
Category members GO Category GO:0001725 stress fiber Database 0.04
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_571 PID_INSULIN_PATHWAY 0 0
Category members Pathway Pathway_949 REACTOME_SMOOTH_MUSCLE_CONTRACTION 0 0
Category members Pathway Pathway_950 REACTOME_MUSCLE_CONTRACTION 0 0
Category members GO Category GO:0005070 SH3/SH2 adaptor activity Database 0
Category members GO Category GO:0005158 insulin receptor binding Database 0
Category members GO Category GO:0005899 insulin receptor complex Database 0
Category members GO Category GO:0005924 cell-substrate adherens junction Database 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0007160 cell-matrix adhesion Database 0
Category members GO Category GO:0043149 stress fiber assembly Database 0
Category members GO Category GO:0045725 positive regulation of glycogen biosynthetic process Database 0
Category members GO Category GO:0046326 positive regulation of glucose import Database 0
Category members GO Category GO:0046889 positive regulation of lipid biosynthetic process Database 0


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