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Query: TLN2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TLN2 0 0.483 -0.680 1.130

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TLN2 Phosphorylation T1843 -0.647 _LDEGT(ph)PPEPK_

Background Information for TLN2:


Pubmed-TLN2 »
Uniprot-TLN2 »
Biogrid-TLN2 »
ProteomicsDB-TLN2 »

Tumorportal-TLN2 »
COSMIC-TLN2 »
GenomeRNAi-TLN2 »
Genecards-TLN2


Protein-protein Interactions for TLN2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait DGCR8 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait L3MBTL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SKP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED10 Cat. description Hein, Mann, Cell 2015
Category members IP bait C13orf15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KANK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TLN2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members FERM_N IPR018979 0.36
Category members Vinculin/catenin IPR006077 0.27
Category members Vinculin-bd_dom IPR015009 0.17
Category members Talin_cent IPR015224 0.17
Category members ILWEQ_dom IPR002558 0.11
Category members FERM_domain IPR000299 0
Category members Insln_rcpt_S1 IPR002404 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring TLN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TLN2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members Pathway Pathway_309 ST_INTEGRIN_SIGNALING_PATHWAY 0 1.35
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_595 KEGG_FOCAL_ADHESION 0 1.08
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0007016 cytoskeletal anchoring at plasma membrane Database 0.74
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0005916 fascia adherens Database 0.47
Category members GO Category GO:0001726 ruffle Database 0.33
Category members GO Category GO:0007043 cell-cell junction assembly Database 0.31
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0005158 insulin receptor binding Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0007155 cell adhesion Database 0


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