RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
TLN1	1	-0.130	0.000	0.807			0.246	0.137
IRS4	0	-0.240	-0.060	-0.868	-1.279	-1.308	-0.107	0.122
IRS1	0
TLN2	0	-0.680	1.130
IRS2	0	-0.190	-0.130

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
IRS1	Phosphorylation	S1101	-0.078		_HSS(ph)ETFSSTPSATR_
IRS2	Phosphorylation	S308	-0.079	-0.510	_SKS(ph)QSSGSSATHPISVPGAR_
IRS2	Phosphorylation	T365	0.641	0.852	_T(ph)ASEGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S367	0.757	0.612	_TAS(ph)EGDGGAAAGAAAAGAR_
IRS2	Phosphorylation	S393	-1.580	-1.221	_PVSVAGSPLS(ph)PGPVR_
IRS2	Phosphorylation	S520	0.359	-1.006	_S(ph)NTPESIAETPPAR_
IRS2	Phosphorylation	T522	-1.103	-0.770	_SNT(ph)PESIAETPPAR_
IRS2	Phosphorylation	T529	0.230	0.164	_S(ph)NTPESIAET(ph)PPAR_
IRS2	Phosphorylation	S562	-0.026	0.439	_RVS(ph)GDAAQDLDR_
IRS2	Phosphorylation	S579	0.542	0.362	_RTYS(ph)LTTPAR_
IRS2	Phosphorylation	S621		-0.190	_LCPSCPAS(ph)SPK_
IRS2	Phosphorylation	S622	-0.195		_LCPSCPASS(ph)PK_
IRS2	Phosphorylation	S681	0.409		_SDDYM(ox)PM(ox)S(ph)PASVSAPK_
IRS2	Phosphorylation	S732	-1.089		_AS(ph)SPAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S733	-1.027	0.522	_ASS(ph)PAESSPEDSGYM(ox)R_
IRS2	Phosphorylation	S738		0.522	_ASS(ph)PAESS(ph)PEDSGYMR_
IRS2	Phosphorylation	S917	-0.592	-1.025	_S(ph)PGEYINIDFGEPGAR_
IRS2	Phosphorylation	S1164		-0.499	_HSSETFSSTTTVTPVS(ph)PSFAHNPK_
IRS2	Phosphorylation	S1178	0.766	0.277	_HNSAS(ph)VENVSLR_
IRS2	Phosphorylation	T1204		-0.454	_SSEGGVGVGPGGGDEPPT(ph)SPR_
IRS2	Phosphorylation	S1205	-0.291		_SSEGGVGVGPGGGDEPPTS(ph)PR_
IRS4	Phosphorylation	S64	-0.090	-0.062	_S(ph)DSESEEEDLPVGEEVCK_
IRS4	Phosphorylation	S66	-0.354	-0.098	_SDS(ph)ESEEEDLPVGEEVCK_
IRS4	Ubiquitylation	K99	-1.384		_YFVLK(gl)LETADAPAR_
IRS4	Ubiquitylation	K202	-0.581	-0.941	_LILESK(gl)R_
IRS4	Ubiquitylation	K240	-0.370	-0.760	_DVWQVIVK(gl)PR_
IRS4	Ubiquitylation	K248	-0.351	-0.699	_K(gl)ELSGVFR_
IRS4	Phosphorylation	S409	-0.928	-0.559	_FVTPSEPVAHS(ph)R_
IRS4	Phosphorylation	S427	-0.406	0.053	_AVS(ph)VPASFFR_
IRS4	Phosphorylation	S439	-1.003	-1.061	_RLAPS(ph)PARPR_
IRS4	Phosphorylation	S457	0.337		_LS(ph)SEVSGSGSGNFGEEGNPQGK_
IRS4	Phosphorylation	S458	0.236		_LSS(ph)EVSGSGSGNFGEEGNPQGK_
IRS4	Ubiquitylation	K618	0.019	0.005	_SYFGK(gl)LTQSK_
IRS4	Ubiquitylation	K674	-0.511	-0.585	_EVK(gl)DAEIPEGAAR_
IRS4	Phosphorylation	Y743	-0.204	0.833	_GY(ph)MMMFPR_
IRS4	Phosphorylation	S751	-1.810	-1.680	_VS(ph)PPPAPS(ph)PPK_
IRS4	Phosphorylation	S757		-2.068	_VS(ph)PPPAPS(ph)PPK_
IRS4	Phosphorylation	T764		-0.886	_APDT(ph)NKEDDSKDNDSESDYMFMAPGAGAIPK_
IRS4	Phosphorylation	S775		-0.869	_APDTNKEDDSKDNDS(ph)ESDYMFMAPGAGAIPK_
IRS4	Phosphorylation	S777	-0.884	-1.011	_APDTNKEDDSKDNDSES(ph)DYMFMAPGAGAIPK_
IRS4	Phosphorylation	Y779	-0.702	-0.231	_APDTNKEDDSKDNDSESDY(ph)MFMAPGAGAIPK_
IRS4	Phosphorylation	S804	-0.814	-0.440	_S(ph)WSSYFSLPNPFR_
IRS4	Phosphorylation	S810		-1.350	_SWSSYFS(ph)LPNPFR_
IRS4	Phosphorylation	S817	-1.106	-1.146	_S(ph)SPLGQNDNSEYVPM(ox)LPGK_
IRS4	Phosphorylation	S818	-1.196	-1.146	_S(ph)SPLGQNDNSEYVPM(ox)LPGK_
IRS4	Phosphorylation	S826	-0.663	-0.805	_SSPLGQNDNS(ph)EYVPM(ox)LPGK_
IRS4	Ubiquitylation	K835	-1.658	-1.572	_SSPLGQNDNSEYVPM(ox)LPGK(gl)FLGR_
IRS4	Phosphorylation	S872		-2.103	_PGDGGS(ph)PSKPSDHEPPK_
IRS4	Ubiquitylation	K897	-0.308	-0.294	_LSFITK(gl)GYK_
IRS4	Phosphorylation	Y921	0.195	-0.259	_EADSSSDY(ph)VNM(ox)DFTK_
IRS4	Ubiquitylation	K928	-0.946	-1.115	_EADSSSDYVNMDFTK(gl)R_
IRS4	Phosphorylation	S931	-0.413	-1.058	_RES(ph)NTPAPSTQGLPDSWGIIAEPR_
IRS4	Phosphorylation	T933		-1.405	_RESNT(ph)PAPSTQGLPDSWGIIAEPR_
IRS4	Phosphorylation	S1061	0.641	0.325	_IYVVDPFSECCM(ox)DISLS(ph)PSR_
IRS4	Phosphorylation	S1091	-0.218	-0.449	_SQS(ph)FFAAAR_
IRS4	Phosphorylation	S1107	-0.374	-0.244	_AAVSAFPTDS(ph)LER_
IRS4	Phosphorylation	S1231		-1.675	_VPRPPEREDS(ph)DNDDDTHVR_
IRS4	Phosphorylation	S1252		-0.763	_RDNQFDS(ph)PKR_
IRS4	Ubiquitylation	K1254	-2.066	-1.156	_RDNQFDSPK(gl)R_
TLN1	Ubiquitylation	K334	-0.489	0.561	_LLGITK(gl)ECVM(ox)R_
TLN1	Phosphorylation	S423		0.105	_DHFGLEGDEESTMLEDS(ph)VSPKK_
TLN1	Phosphorylation	S425	-0.366	-0.322	_DHFGLEGDEESTMLEDSVS(ph)PKK_
TLN1	Ubiquitylation	K869	-0.260		_ILADATAK(gl)MVEAAK_
TLN1	Ubiquitylation	K1541	0.365	2.311	_EVANSTANLVK(gl)TIK_
TLN1	Ubiquitylation	K2021	0.309	0.479	_EGILK(gl)TAK_
TLN2	Phosphorylation	T1843	-0.647		_LDEGT(ph)PPEPK_