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Query: SP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SP3 1 1.240 2.510 -0.930 -0.403 0.807 0.836

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SP3:


Pubmed-SP3 »
Uniprot-SP3 »
Biogrid-SP3 »
ProteomicsDB-SP3 »

Tumorportal-SP3 »
COSMIC-SP3 »
GenomeRNAi-SP3 »
Genecards-SP3


Protein-protein Interactions for SP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SGCZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members Galactose-bd-like IPR008979 0


Protein complexes (CORUM database) featuring SP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016605 PML body Database 1.41
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0001889 liver development Database 0.51
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0030224 monocyte differentiation Database 0.45
Category members GO Category GO:0030324 lung development Database 0.39
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0060216 definitive hemopoiesis Database 0.18
Category members GO Category GO:0030218 erythrocyte differentiation Database 0.13
Category members Pathway Pathway_698 BIOCARTA_CALCINEURIN_PATHWAY 0 0.11
Category members GO Category GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding Database 0.05
Category members GO Category GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Database 0.04
Category members GO Category GO:0060136 embryonic process involved in female pregnancy Database 0.04
Category members GO Category GO:0048596 embryonic camera-type eye morphogenesis Database 0.01
Category members GO Category GO:0000987 core promoter proximal region sequence-specific DNA binding Database 0
Category members GO Category GO:0001503 ossification Database 0
Category members GO Category GO:0001779 natural killer cell differentiation Database 0
Category members GO Category GO:0001829 trophectodermal cell differentiation Database 0
Category members GO Category GO:0001892 embryonic placenta development Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0030183 B cell differentiation Database 0
Category members GO Category GO:0030217 T cell differentiation Database 0
Category members GO Category GO:0030219 megakaryocyte differentiation Database 0
Category members GO Category GO:0030851 granulocyte differentiation Database 0
Category members GO Category GO:0043353 enucleate erythrocyte differentiation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048706 embryonic skeletal system development Database 0


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